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The map label for this gene is fur [H]

Identifier: 118579210

GI number: 118579210

Start: 820680

End: 821123

Strand: Direct

Name: fur [H]

Synonym: Ppro_0772

Alternate gene names: 118579210

Gene position: 820680-821123 (Clockwise)

Preceding gene: 118579209

Following gene: 118579211

Centisome position: 20.48

GC content: 58.78

Gene sequence:

>444_bases
ATGATTCTCGAAAAGAAGCATGCGTTCAACAGGTTTGCCGCGGGCAAGGGGCTGCGCTCCACCAGGCAGCGCGAAATCAT
CCTTGATTTCTTCCTCGCCACCCATCAGCACGTCAGCGTCGAAGAGTTGTATCTGAAGATCAAGGCGGTGCATCCCGGCA
TTGGTAGCGCAACGGTTTACCGCACCCTCAAGCTGTTCGTTGAGGCCGGACTGGCCCGCGAGGTGCTGCTGCATGACGGG
CAGACCCGCTACGAACATGTGGTGGAAGGTGAGCACCACGATCACCTGGTCTGTACCGGCTGCAACGCGGTCATCGAGTT
CGAGAACGAGACCATCGAGAAGTTGCAGGATGAGATCGCCACCCGCCACGGTTTTCTGATCAAGAGTCACAAGCTGGAGA
TTTACGGGCTCTGCGCCCGCTGCCGCGCAGCGGCGAAGACCTAG

Upstream 100 bases:

>100_bases
ATTTTCCGATTTCTTCCTGTGTCCACCTGTGCCAAAAAATACTTGACAGCTGACCGGTATCTTCTTATCTTGAAATTCAA
CTTCAACAAAGGGGGGGCGG

Downstream 100 bases:

>100_bases
CCCATCCAACGCCTCTCACCGTCTCGGGAACTGTTTTTTTGTGTATGTGAAAATGAATGTCAAGAACATGGATAGGGTGT
GATTGTATGGCATCATGTTG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MILEKKHAFNRFAAGKGLRSTRQREIILDFFLATHQHVSVEELYLKIKAVHPGIGSATVYRTLKLFVEAGLAREVLLHDG
QTRYEHVVEGEHHDHLVCTGCNAVIEFENETIEKLQDEIATRHGFLIKSHKLEIYGLCARCRAAAKT

Sequences:

>Translated_147_residues
MILEKKHAFNRFAAGKGLRSTRQREIILDFFLATHQHVSVEELYLKIKAVHPGIGSATVYRTLKLFVEAGLAREVLLHDG
QTRYEHVVEGEHHDHLVCTGCNAVIEFENETIEKLQDEIATRHGFLIKSHKLEIYGLCARCRAAAKT
>Mature_147_residues
MILEKKHAFNRFAAGKGLRSTRQREIILDFFLATHQHVSVEELYLKIKAVHPGIGSATVYRTLKLFVEAGLAREVLLHDG
QTRYEHVVEGEHHDHLVCTGCNAVIEFENETIEKLQDEIATRHGFLIKSHKLEIYGLCARCRAAAKT

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=129, Percent_Identity=40.3100775193798, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16704; Mature: 16704

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILEKKHAFNRFAAGKGLRSTRQREIILDFFLATHQHVSVEELYLKIKAVHPGIGSATVY
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCCHHHHH
RTLKLFVEAGLAREVLLHDGQTRYEHVVEGEHHDHLVCTGCNAVIEFENETIEKLQDEIA
HHHHHHHHHCHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCEEEEECHHHHHHHHHHHH
TRHGFLIKSHKLEIYGLCARCRAAAKT
HHCCEEEECCCCCEEHHHHHHHHHCCC
>Mature Secondary Structure
MILEKKHAFNRFAAGKGLRSTRQREIILDFFLATHQHVSVEELYLKIKAVHPGIGSATVY
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCCHHHHH
RTLKLFVEAGLAREVLLHDGQTRYEHVVEGEHHDHLVCTGCNAVIEFENETIEKLQDEIA
HHHHHHHHHCHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCEEEEECHHHHHHHHHHHH
TRHGFLIKSHKLEIYGLCARCRAAAKT
HHCCEEEECCCCCEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]