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The map label for this gene is ytfL [C]

Identifier: 118579200

GI number: 118579200

Start: 804804

End: 806174

Strand: Direct

Name: ytfL [C]

Synonym: Ppro_0762

Alternate gene names: 118579200

Gene position: 804804-806174 (Clockwise)

Preceding gene: 118579199

Following gene: 118579201

Centisome position: 20.08

GC content: 60.39

Gene sequence:

>1371_bases
TTGTCGGAACCTGTGGTTGACATTCTCCAATGCAAAGGTGAAAATGCCGCAATTCCTGGGGAGGTAAGCGTGGATTCCAT
TCTGCTGGAAGTGCTGGTTATCTGTCTGATGATCGTACTGAACGGCTTTTTTGCCTGTTCCGAATTCGCCATCGTATCGG
TGCGCAAGAGCCGCATTGCCCGTCTGGTGTTGGATGGGGACGAACGGGCGCGGATCGTCGAGACGCTCCAGCAGGACCCC
CACCGGTTGCTGGCGCTGGTGCAGATCGGGGTGACAGTGGCCGGTTCAGCCGCATCCACCGTCGGCGGCATCATCGCCAT
CGAACACCTGCGCCCCTTCTTTGCTACTCTCCCCTGGCCCCTGATACAGAAATCGGCGGAACCGCTGGCCGTGATCACGG
TGGTGGTCCTGGTGTCCTATGTCTCACTGATTGTGGGTGAGCTGGTACCCAAAGCTATCGGCCTGCAGTACGCCGACGCT
ATTGCCCTGCGGGTTGCGCGTCCCATCGACTTCCTCTCACGGGTGGGGTCCCTGGCGGTGAGTGTTTTGACCATCTCCAG
CAAGGCGGTGATGAAGTTACTGCGTGTCAGCGGCGACCGCCAGGGGTTCATCACCCGCGAGGAGTTACAGCATTTCGTTG
CCGAGGGACGCGAGAGCGGGGTTTTCAGCGAGACCGAGACGGAATACATCCACAATGTTTTCGAATTCACCCACACCTGC
GTACGCGAGGTGATGGTGCCGCGCACCCGTATCGTGGGGCTCGAGCTGGGCACCTCCCGTGATCAGGTCGTGTCGGTGAT
TCTGGAGAACATGTACTCCCGCTACCCGGTCTATAGCGGGACCATAGAAGACGTTGTCGGCGTGGTGCATGGCAAGGATC
TGCTGGGCCGGATGGTGGCCGGCGAGCCGTTCGATCTCGCCGCCACCATGAAAGCGCCGGTATTTGTTCCGGAGAGCAAG
ATGGTCAACGAACTGCTCAAGGAGATGCAACGCAGCCAGAACCAGATGGCGATGGTGGTGGACGAGTATGGCGGCCTGAA
TGGCCTGGTTACCTCCCAGGATTTGATCGAAGAGCTGCTGGGCGAGATCCGCGATGAACACGATACCGCCGAGACCGCCG
GCATTCAGCGCCTGGCGGACGGCTCCCTGCTGGTTGACGGCTTCTTCTCCATTTTCGACCTGGCTGAATTCCTTGAGATC
AGACAGGTCGCGGATCTCCCCTACGATACGGTCGCCGGAATGATCCTGGACGCCCTGGGTCGCTTCCCGCAGCGTGGTGA
AGGCGTGGTCTGGCAGGGGTACCGCTTCACCTGTGAAGACGTCACCAGGACGGCCATCCTGCGGGTGCGGGTCGTGGCGG
CGGGGGAATAG

Upstream 100 bases:

>100_bases
TGAAAAGAGCCTGTCGGAGCCATCTGACAGGCTCTTTTCGCGTTTGGGGCGCCGCGCGTTCTGCGGGACCGGTGCCATCC
GGCATGGCCAAAGGGGATAA

Downstream 100 bases:

>100_bases
CGCAACCATGCTCAAGCGTCTGCATATCCGCCTGCCCGCGCTCCTGCTGCTCTTCCTGGTTTCGGGGCTGATCGGGCTGG
CACTGTTCCTGCCGCGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSEPVVDILQCKGENAAIPGEVSVDSILLEVLVICLMIVLNGFFACSEFAIVSVRKSRIARLVLDGDERARIVETLQQDP
HRLLALVQIGVTVAGSAASTVGGIIAIEHLRPFFATLPWPLIQKSAEPLAVITVVVLVSYVSLIVGELVPKAIGLQYADA
IALRVARPIDFLSRVGSLAVSVLTISSKAVMKLLRVSGDRQGFITREELQHFVAEGRESGVFSETETEYIHNVFEFTHTC
VREVMVPRTRIVGLELGTSRDQVVSVILENMYSRYPVYSGTIEDVVGVVHGKDLLGRMVAGEPFDLAATMKAPVFVPESK
MVNELLKEMQRSQNQMAMVVDEYGGLNGLVTSQDLIEELLGEIRDEHDTAETAGIQRLADGSLLVDGFFSIFDLAEFLEI
RQVADLPYDTVAGMILDALGRFPQRGEGVVWQGYRFTCEDVTRTAILRVRVVAAGE

Sequences:

>Translated_456_residues
MSEPVVDILQCKGENAAIPGEVSVDSILLEVLVICLMIVLNGFFACSEFAIVSVRKSRIARLVLDGDERARIVETLQQDP
HRLLALVQIGVTVAGSAASTVGGIIAIEHLRPFFATLPWPLIQKSAEPLAVITVVVLVSYVSLIVGELVPKAIGLQYADA
IALRVARPIDFLSRVGSLAVSVLTISSKAVMKLLRVSGDRQGFITREELQHFVAEGRESGVFSETETEYIHNVFEFTHTC
VREVMVPRTRIVGLELGTSRDQVVSVILENMYSRYPVYSGTIEDVVGVVHGKDLLGRMVAGEPFDLAATMKAPVFVPESK
MVNELLKEMQRSQNQMAMVVDEYGGLNGLVTSQDLIEELLGEIRDEHDTAETAGIQRLADGSLLVDGFFSIFDLAEFLEI
RQVADLPYDTVAGMILDALGRFPQRGEGVVWQGYRFTCEDVTRTAILRVRVVAAGE
>Mature_455_residues
SEPVVDILQCKGENAAIPGEVSVDSILLEVLVICLMIVLNGFFACSEFAIVSVRKSRIARLVLDGDERARIVETLQQDPH
RLLALVQIGVTVAGSAASTVGGIIAIEHLRPFFATLPWPLIQKSAEPLAVITVVVLVSYVSLIVGELVPKAIGLQYADAI
ALRVARPIDFLSRVGSLAVSVLTISSKAVMKLLRVSGDRQGFITREELQHFVAEGRESGVFSETETEYIHNVFEFTHTCV
REVMVPRTRIVGLELGTSRDQVVSVILENMYSRYPVYSGTIEDVVGVVHGKDLLGRMVAGEPFDLAATMKAPVFVPESKM
VNELLKEMQRSQNQMAMVVDEYGGLNGLVTSQDLIEELLGEIRDEHDTAETAGIQRLADGSLLVDGFFSIFDLAEFLEIR
QVADLPYDTVAGMILDALGRFPQRGEGVVWQGYRFTCEDVTRTAILRVRVVAAGE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=384, Percent_Identity=28.6458333333333, Blast_Score=191, Evalue=2e-48,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=25.8064516129032, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI145693175, Length=424, Percent_Identity=25.2358490566038, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786879, Length=248, Percent_Identity=31.8548387096774, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87082033, Length=269, Percent_Identity=27.1375464684015, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788119, Length=249, Percent_Identity=26.5060240963855, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49919; Mature: 49787

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPVVDILQCKGENAAIPGEVSVDSILLEVLVICLMIVLNGFFACSEFAIVSVRKSRIA
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVLDGDERARIVETLQQDPHRLLALVQIGVTVAGSAASTVGGIIAIEHLRPFFATLPWP
HHEECCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCH
LIQKSAEPLAVITVVVLVSYVSLIVGELVPKAIGLQYADAIALRVARPIDFLSRVGSLAV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLTISSKAVMKLLRVSGDRQGFITREELQHFVAEGRESGVFSETETEYIHNVFEFTHTC
HHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
VREVMVPRTRIVGLELGTSRDQVVSVILENMYSRYPVYSGTIEDVVGVVHGKDLLGRMVA
HHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHC
GEPFDLAATMKAPVFVPESKMVNELLKEMQRSQNQMAMVVDEYGGLNGLVTSQDLIEELL
CCCCCCHHHCCCCEECCCHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCHHHHHHHH
GEIRDEHDTAETAGIQRLADGSLLVDGFFSIFDLAEFLEIRQVADLPYDTVAGMILDALG
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
RFPQRGEGVVWQGYRFTCEDVTRTAILRVRVVAAGE
CCCCCCCCEEECCCEEEHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
SEPVVDILQCKGENAAIPGEVSVDSILLEVLVICLMIVLNGFFACSEFAIVSVRKSRIA
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVLDGDERARIVETLQQDPHRLLALVQIGVTVAGSAASTVGGIIAIEHLRPFFATLPWP
HHEECCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCH
LIQKSAEPLAVITVVVLVSYVSLIVGELVPKAIGLQYADAIALRVARPIDFLSRVGSLAV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLTISSKAVMKLLRVSGDRQGFITREELQHFVAEGRESGVFSETETEYIHNVFEFTHTC
HHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
VREVMVPRTRIVGLELGTSRDQVVSVILENMYSRYPVYSGTIEDVVGVVHGKDLLGRMVA
HHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHC
GEPFDLAATMKAPVFVPESKMVNELLKEMQRSQNQMAMVVDEYGGLNGLVTSQDLIEELL
CCCCCCHHHCCCCEECCCHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCHHHHHHHH
GEIRDEHDTAETAGIQRLADGSLLVDGFFSIFDLAEFLEIRQVADLPYDTVAGMILDALG
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
RFPQRGEGVVWQGYRFTCEDVTRTAILRVRVVAAGE
CCCCCCCCEEECCCEEEHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]