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The map label for this gene is ntrY [H]

Identifier: 118579148

GI number: 118579148

Start: 737977

End: 740193

Strand: Direct

Name: ntrY [H]

Synonym: Ppro_0709

Alternate gene names: 118579148

Gene position: 737977-740193 (Clockwise)

Preceding gene: 118579146

Following gene: 118579149

Centisome position: 18.41

GC content: 51.11

Gene sequence:

>2217_bases
ATGGGATACAAACTGTCAATCAATGAGCGCAAAAAACGTGCCCGTGAAGCAATCGTTATTGTTGTTGCTTTGCTGTTGAT
TCTCTTTCTAACATCCGCGGAAATACGCCTTACCCAGTTAAGCGCAGATACATCAATGGGCAGCAACATCATGATCTTCG
GCATCATCAATGTTGTGGTGTTGTTGGTAATTCTGCTGGTGTATCTGGTAAGCCGTAATGTAGTCAAACTGCTATTGGAG
AACCGCTCCAATCCTGTTGCTACACGCCTGAGAACGAAGCTGGTCGTATCGTTTGTGGGTCTGTCCTTGGTGCCGACCTT
GTTGCTTTTCTTCGCTGCGGCTGGTTTTATCAACAATACTGTACATAACTGGTTTAACACCCAGGTTGAAACGTCGCTTA
GCGAGTCTTTGGAGGTTGCCCAGACCTATTACAAGAACTCGGCGTCCAACACGATTTACTACGGACGTCAGATCAGCGCC
ATCATCCGCTCCTCGAAACTGCTTAACCAGGAAAATCTGCCCAAGCTTGAAGCGCTAATCAGGCAGAAGCAGAAGGAATA
TAATCTCGGTGTCGTCGAGGTCTACTCTGCCCAGCAGGAGGAACTAGTTCGCGCCACAAACCCTCTGGTTCCCAGGGGAG
AGTTTACCAACCCTGCTTCGGATGATATCGTTCGTGCGCTGTCAGGTAATGAATTGACCAGGATTAACCCGGTCGGCAAG
GCTGATCTGATACGGGGAATAGTGCCGATATATTCAACCTGGAATGATCGTGATGTGGTTGGGGCGGTGGTGGTCAATTA
TTACGTACCCTATTCGCTGGTCAATAAAATGAAGGAAATCACCGAGTCGTACCACGAGTTCCGACAGCTGAAAATTATGA
AGAACCCGATACGCACCGGTTATATCGTCACGCTCTTCTTGATTACTGTAGTTATTGTGTTCCTAGCCTATTGGATAGCC
GTGTATCTGGCCAACAGTATGTCAAAGCCGGTACAGGAACTGCTTGAGGCAACCCGTGCTGTTGCGGAGGGCAATCTCGA
CGTACAGATAGAAAGTGCCTCGCTGGACGAAATCGGCATGCTTGTCACTTCGTTCAATCGCATGACCACTGACTTGCGTA
CTAAGCAGCAGACCTTAAACGCGGTAAACCATGAATTGACCAAGATCAACCTGGAACTGGATCAGCGGCGGCGTTACATG
GAGATCGTGCTTCGCAATGTTGCCGCGGGTGTAATCTCCATTGACAGGGAAGGGTGCATTACCACCATTAATAAGTCAGC
GGAGAAACTGCTCAGCATCTCAAATGGCGCGGTTGTGGGGCGCAATTTTCGAGAGTTGCTGCAGGATGCCCACCTCGATA
TCGTTAAGGACATACTGCGCGACCTGCTCCTGTCAAAGCAAGACACCATAAACCGGCAGATCGTTCTCGATGTAAATGGG
AACCGGCTGGCACTGCATCTGCATCTGAATATGTTGCGCGATGAAAATGGAAGCTTTGTGGGCACCGTGCTGGTGCTGGA
CGACCTGACCCAGGTCATGAAGGTGCAGCGCATGGCCGCTTGGCGGGAGGTTGCCAGGCGCATAGCCCATGAGATAAAGA
ATCCGCTCACCCCGATACAGCTTTCCGCCCAGCGGCTTCGGAAACGCTACCTTTCGCGCTTCAGCGACGATGAAAAGGTC
TTTGACGAATGTACGGAAATGATAATAAAGTCGGTGGATGATCTTAAGAATCTGGTGAACGAGTTTTCCAACTTTGCCCG
CATGCCCGCCATACAACCGGAGCCCAACGACCTGAACGATATCATTCGTGAGGCGCTGACACTGTACCAGCAGGCACATC
GCGATGTGCAGTTCGATTTCAAGCCCGATAGCAGGCTGCCGTTTCTGAAAATTGACCGCAGCCAGATCAAGCGCGTTGTC
ATCAATCTGCTGGAGAATGCCGTTGCTGCCATGGATGGACAGGGGACGGTCAGGATAGTCTCTAACTACGACGCTGAACT
GAGGCTGGCCTCGTTCGTTGTTGTCGATACCGGTCCGGGTATACCTGCCGAGGACAAGCCTCGCCTGTTCGAACCTTATT
TCTCAACTAAGAAGACCGGGACTGGCCTCGGCCTGGCTATCGTCAACAGCGTCGTGTCCGATCACAACGGGTTTGTGCGT
ATCAGGGACAATGATCCCCATGGAGCCTGCTTCGTCGTTGAACTTCCCGCTGCCTGA

Upstream 100 bases:

>100_bases
ACGCTGCTGTCTGTCCGCTCTGAATGTGATTGTGTGTTTCATAAGGAACAGGATGACAATCGAAGCGTCTGACCATTACC
TGAGGACTATGTAACGGAGC

Downstream 100 bases:

>100_bases
GTGAGCTGCGCTGACCAGGGTAAGAGTGGGACGGGCCGGTCTCTGGCCGTGCAAAAGAGAGGAGCATATGTCGAAATTAA
TACTTGTGGTGGATGATGAG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 738; Mature: 737

Protein sequence:

>738_residues
MGYKLSINERKKRAREAIVIVVALLLILFLTSAEIRLTQLSADTSMGSNIMIFGIINVVVLLVILLVYLVSRNVVKLLLE
NRSNPVATRLRTKLVVSFVGLSLVPTLLLFFAAAGFINNTVHNWFNTQVETSLSESLEVAQTYYKNSASNTIYYGRQISA
IIRSSKLLNQENLPKLEALIRQKQKEYNLGVVEVYSAQQEELVRATNPLVPRGEFTNPASDDIVRALSGNELTRINPVGK
ADLIRGIVPIYSTWNDRDVVGAVVVNYYVPYSLVNKMKEITESYHEFRQLKIMKNPIRTGYIVTLFLITVVIVFLAYWIA
VYLANSMSKPVQELLEATRAVAEGNLDVQIESASLDEIGMLVTSFNRMTTDLRTKQQTLNAVNHELTKINLELDQRRRYM
EIVLRNVAAGVISIDREGCITTINKSAEKLLSISNGAVVGRNFRELLQDAHLDIVKDILRDLLLSKQDTINRQIVLDVNG
NRLALHLHLNMLRDENGSFVGTVLVLDDLTQVMKVQRMAAWREVARRIAHEIKNPLTPIQLSAQRLRKRYLSRFSDDEKV
FDECTEMIIKSVDDLKNLVNEFSNFARMPAIQPEPNDLNDIIREALTLYQQAHRDVQFDFKPDSRLPFLKIDRSQIKRVV
INLLENAVAAMDGQGTVRIVSNYDAELRLASFVVVDTGPGIPAEDKPRLFEPYFSTKKTGTGLGLAIVNSVVSDHNGFVR
IRDNDPHGACFVVELPAA

Sequences:

>Translated_738_residues
MGYKLSINERKKRAREAIVIVVALLLILFLTSAEIRLTQLSADTSMGSNIMIFGIINVVVLLVILLVYLVSRNVVKLLLE
NRSNPVATRLRTKLVVSFVGLSLVPTLLLFFAAAGFINNTVHNWFNTQVETSLSESLEVAQTYYKNSASNTIYYGRQISA
IIRSSKLLNQENLPKLEALIRQKQKEYNLGVVEVYSAQQEELVRATNPLVPRGEFTNPASDDIVRALSGNELTRINPVGK
ADLIRGIVPIYSTWNDRDVVGAVVVNYYVPYSLVNKMKEITESYHEFRQLKIMKNPIRTGYIVTLFLITVVIVFLAYWIA
VYLANSMSKPVQELLEATRAVAEGNLDVQIESASLDEIGMLVTSFNRMTTDLRTKQQTLNAVNHELTKINLELDQRRRYM
EIVLRNVAAGVISIDREGCITTINKSAEKLLSISNGAVVGRNFRELLQDAHLDIVKDILRDLLLSKQDTINRQIVLDVNG
NRLALHLHLNMLRDENGSFVGTVLVLDDLTQVMKVQRMAAWREVARRIAHEIKNPLTPIQLSAQRLRKRYLSRFSDDEKV
FDECTEMIIKSVDDLKNLVNEFSNFARMPAIQPEPNDLNDIIREALTLYQQAHRDVQFDFKPDSRLPFLKIDRSQIKRVV
INLLENAVAAMDGQGTVRIVSNYDAELRLASFVVVDTGPGIPAEDKPRLFEPYFSTKKTGTGLGLAIVNSVVSDHNGFVR
IRDNDPHGACFVVELPAA
>Mature_737_residues
GYKLSINERKKRAREAIVIVVALLLILFLTSAEIRLTQLSADTSMGSNIMIFGIINVVVLLVILLVYLVSRNVVKLLLEN
RSNPVATRLRTKLVVSFVGLSLVPTLLLFFAAAGFINNTVHNWFNTQVETSLSESLEVAQTYYKNSASNTIYYGRQISAI
IRSSKLLNQENLPKLEALIRQKQKEYNLGVVEVYSAQQEELVRATNPLVPRGEFTNPASDDIVRALSGNELTRINPVGKA
DLIRGIVPIYSTWNDRDVVGAVVVNYYVPYSLVNKMKEITESYHEFRQLKIMKNPIRTGYIVTLFLITVVIVFLAYWIAV
YLANSMSKPVQELLEATRAVAEGNLDVQIESASLDEIGMLVTSFNRMTTDLRTKQQTLNAVNHELTKINLELDQRRRYME
IVLRNVAAGVISIDREGCITTINKSAEKLLSISNGAVVGRNFRELLQDAHLDIVKDILRDLLLSKQDTINRQIVLDVNGN
RLALHLHLNMLRDENGSFVGTVLVLDDLTQVMKVQRMAAWREVARRIAHEIKNPLTPIQLSAQRLRKRYLSRFSDDEKVF
DECTEMIIKSVDDLKNLVNEFSNFARMPAIQPEPNDLNDIIREALTLYQQAHRDVQFDFKPDSRLPFLKIDRSQIKRVVI
NLLENAVAAMDGQGTVRIVSNYDAELRLASFVVVDTGPGIPAEDKPRLFEPYFSTKKTGTGLGLAIVNSVVSDHNGFVRI
RDNDPHGACFVVELPAA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=367, Percent_Identity=26.4305177111717, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=28.82096069869, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=28.080229226361, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789808, Length=216, Percent_Identity=29.1666666666667, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=28.099173553719, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=372, Percent_Identity=24.4623655913978, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=26.2589928057554, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=27.1111111111111, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=28.3185840707965, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83164; Mature: 83032

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYKLSINERKKRAREAIVIVVALLLILFLTSAEIRLTQLSADTSMGSNIMIFGIINVVV
CCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEHHHHHHHHH
LLVILLVYLVSRNVVKLLLENRSNPVATRLRTKLVVSFVGLSLVPTLLLFFAAAGFINNT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHNWFNTQVETSLSESLEVAQTYYKNSASNTIYYGRQISAIIRSSKLLNQENLPKLEALI
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHH
RQKQKEYNLGVVEVYSAQQEELVRATNPLVPRGEFTNPASDDIVRALSGNELTRINPVGK
HHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCH
ADLIRGIVPIYSTWNDRDVVGAVVVNYYVPYSLVNKMKEITESYHEFRQLKIMKNPIRTG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YIVTLFLITVVIVFLAYWIAVYLANSMSKPVQELLEATRAVAEGNLDVQIESASLDEIGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
LVTSFNRMTTDLRTKQQTLNAVNHELTKINLELDQRRRYMEIVLRNVAAGVISIDREGCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHEEECCCCCH
TTINKSAEKLLSISNGAVVGRNFRELLQDAHLDIVKDILRDLLLSKQDTINRQIVLDVNG
HHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
NRLALHLHLNMLRDENGSFVGTVLVLDDLTQVMKVQRMAAWREVARRIAHEIKNPLTPIQ
CEEEEEEEEEHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LSAQRLRKRYLSRFSDDEKVFDECTEMIIKSVDDLKNLVNEFSNFARMPAIQPEPNDLND
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IIREALTLYQQAHRDVQFDFKPDSRLPFLKIDRSQIKRVVINLLENAVAAMDGQGTVRIV
HHHHHHHHHHHHCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SNYDAELRLASFVVVDTGPGIPAEDKPRLFEPYFSTKKTGTGLGLAIVNSVVSDHNGFVR
ECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEE
IRDNDPHGACFVVELPAA
EEECCCCCEEEEEECCCC
>Mature Secondary Structure 
GYKLSINERKKRAREAIVIVVALLLILFLTSAEIRLTQLSADTSMGSNIMIFGIINVVV
CEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEHHHHHHHHH
LLVILLVYLVSRNVVKLLLENRSNPVATRLRTKLVVSFVGLSLVPTLLLFFAAAGFINNT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHNWFNTQVETSLSESLEVAQTYYKNSASNTIYYGRQISAIIRSSKLLNQENLPKLEALI
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHH
RQKQKEYNLGVVEVYSAQQEELVRATNPLVPRGEFTNPASDDIVRALSGNELTRINPVGK
HHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCH
ADLIRGIVPIYSTWNDRDVVGAVVVNYYVPYSLVNKMKEITESYHEFRQLKIMKNPIRTG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YIVTLFLITVVIVFLAYWIAVYLANSMSKPVQELLEATRAVAEGNLDVQIESASLDEIGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
LVTSFNRMTTDLRTKQQTLNAVNHELTKINLELDQRRRYMEIVLRNVAAGVISIDREGCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHEEECCCCCH
TTINKSAEKLLSISNGAVVGRNFRELLQDAHLDIVKDILRDLLLSKQDTINRQIVLDVNG
HHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
NRLALHLHLNMLRDENGSFVGTVLVLDDLTQVMKVQRMAAWREVARRIAHEIKNPLTPIQ
CEEEEEEEEEHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LSAQRLRKRYLSRFSDDEKVFDECTEMIIKSVDDLKNLVNEFSNFARMPAIQPEPNDLND
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IIREALTLYQQAHRDVQFDFKPDSRLPFLKIDRSQIKRVVINLLENAVAAMDGQGTVRIV
HHHHHHHHHHHHCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SNYDAELRLASFVVVDTGPGIPAEDKPRLFEPYFSTKKTGTGLGLAIVNSVVSDHNGFVR
ECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEE
IRDNDPHGACFVVELPAA
EEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]