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The map label for this gene is kup

Identifier: 118579049

GI number: 118579049

Start: 646012

End: 647829

Strand: Reverse

Name: kup

Synonym: Ppro_0610

Alternate gene names: 118579049

Gene position: 647829-646012 (Counterclockwise)

Preceding gene: 118579053

Following gene: 118579024

Centisome position: 16.16

GC content: 60.29

Gene sequence:

>1818_bases
ATGAAGCATGGCGAAACCGATTCCTACTGGGGCGGCATCATCAAATCCATGGGGCTGGTATTCGGCGACATCGGCACCAG
CCCGATCTACACCCTGACCGTCATCATCGCCCTCACCAAACCGACCCAGGACAACATCCTCGGCATCATCTCCCTGATCG
TCTGGACCCTGATCATCCTGGTACACCTGGAGTACGCCGTACTGGCCATGAGCCTGAGCCGCAAGGGGGAGGGGGGGGAG
ATCGTGCTGCGCGAGATCCTGGTACGAATGATCAAGCCTGGCCGCCAGATGGCCTTCGTCACCTTCCTCACCTACCTGGG
GGTGGCCCTGCTCATGGGGGACGGCGTGATCACCCCGGCCATCAGTATCCTCTCGGCAGTGGAAGGAACCTTGCTGATCC
CGGGCCTGGGCGGCCTGAGCCAGAACACGCTGATCCTGATCGCTGGCACGATCGCCCTGTTCCTGTTCGTCTTCCAGTAC
AAGGGGACCGACAAGGTGGCCCGGGCCTTCGGGCCGATCATGGTGCTCTGGTTCGCGGCCCTGGCACTATCGGGTGCAAT
TTCCGTCTCCTCCCACCCCGGCATCCTGGCAGCCATCAGCCCGCACCACGCCATCTCCTTCCTGATGCACAACGGTCTCC
CCGGTTTCTTCGTGCTCTCCGAAGTGATCCTCTGCGCCACCGGGGGCGAGGCGCTCTACGCCGACATGGGACACCTGGGG
CGCAAGCCGGTCAAACGGGCCTGGTATTTCGTCTTCGTCGCCCTGGTGATCAACTACCTGGGTCAGGGAGCCTTCATCAT
CACCCACCCGGATGCCAAGAACATCCTCTTCGGCATGCTTCAGTACCAGGCGCCCCTGTTCTACATTCCCTTCCTGATCC
TGACGATCCTGGCCACCATCATCGCCTCCCAGGCACTGATCAGCGGCGTCTTCTCCATCGTCTACCAGGGGATCAACACC
CGCATGCTGCCGCTGCTCAAGGTGGACTACACATCCAACCAGCTCAAGTCCCAGATCTATATCGGCTCGGTCAACTGGCT
GTTGCTCTGTTTGGTGATCCTGATCATGCTGGTCTTCAGGAAGTCCGCCAACCTGGCGGCCGCCTATGGATTTGCCGTCA
CCGGCACCATGGTCATCACCGGCATCATGATGACCATGATCTTCAGCCGCACCACCAAGAAGTGGAAGGTTCCTCTGGCA
CTGTTCGTCACCCTGGTGGACGTGGTCTTCCTGGTATCGAACTGCAACAAACTGCCCCATGGCGGCTACTGGTCGCTGAT
CCTGGCCTCGGTCCCCCTGGCCGTGATCCTGATCTGGACCAGGGGTCAGCGCGGCCTCTACCTGGCCCTGCGCCCGCTGG
ACCTGGAGACCTACCTGCTGAGCTATGAGCAGATCTACAAGAAGGGGCGCATCGCCGGCACCGGCCTGTTCTTCGTCAAG
GAGTGGAACATCATCCCCCCCTACCTGGTGCACTGCACCATCCGCAGCAACATCGTCTATGAGCGCAACGTGCTGATCTC
CATCGTCCGCACCGACGAACCCTTCGGCGTGGAGTCCGTGCTGGAGTGCGGCATCGGCACCGGCCTGGATGGCTTCATGA
TCAAGGCCGGCTACATGGAAATCTTCGATATCGAGCTACTGCTGAAACAGAACGGCATCCAGGAGAAGGTCATTTTCTAC
GGCATCGAGGATATCGCCACCACAAACCCGATCTGGAGGGTCTTCTCGGTGATCAAGAAGCTGACACCCAACTTCGTGCA
GTTCAACAAGGTCCCGGCTGCCAAGCTGCAGGGGGTCATCACCAGGGTGGAGATGTAG

Upstream 100 bases:

>100_bases
TGCCTGCGGCCCTTTTTTGCATTTCGTCCGGCCCGTGGTACAAATCATTGGTGCGCGGGCCGGCCCCTGAAAGCGGGCGG
CAGCAGCGCGGAGGCCTGAC

Downstream 100 bases:

>100_bases
CCTCCACTTGAACGCCCGTCAGGCTGGTGGGGCTGTCCGCGGGAAGCGACTTATCCCTGATCCGTCGTGGTTCCCGGCGA
AATGGAGCGAAAGGCAGCCG

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MKHGETDSYWGGIIKSMGLVFGDIGTSPIYTLTVIIALTKPTQDNILGIISLIVWTLIILVHLEYAVLAMSLSRKGEGGE
IVLREILVRMIKPGRQMAFVTFLTYLGVALLMGDGVITPAISILSAVEGTLLIPGLGGLSQNTLILIAGTIALFLFVFQY
KGTDKVARAFGPIMVLWFAALALSGAISVSSHPGILAAISPHHAISFLMHNGLPGFFVLSEVILCATGGEALYADMGHLG
RKPVKRAWYFVFVALVINYLGQGAFIITHPDAKNILFGMLQYQAPLFYIPFLILTILATIIASQALISGVFSIVYQGINT
RMLPLLKVDYTSNQLKSQIYIGSVNWLLLCLVILIMLVFRKSANLAAAYGFAVTGTMVITGIMMTMIFSRTTKKWKVPLA
LFVTLVDVVFLVSNCNKLPHGGYWSLILASVPLAVILIWTRGQRGLYLALRPLDLETYLLSYEQIYKKGRIAGTGLFFVK
EWNIIPPYLVHCTIRSNIVYERNVLISIVRTDEPFGVESVLECGIGTGLDGFMIKAGYMEIFDIELLLKQNGIQEKVIFY
GIEDIATTNPIWRVFSVIKKLTPNFVQFNKVPAAKLQGVITRVEM

Sequences:

>Translated_605_residues
MKHGETDSYWGGIIKSMGLVFGDIGTSPIYTLTVIIALTKPTQDNILGIISLIVWTLIILVHLEYAVLAMSLSRKGEGGE
IVLREILVRMIKPGRQMAFVTFLTYLGVALLMGDGVITPAISILSAVEGTLLIPGLGGLSQNTLILIAGTIALFLFVFQY
KGTDKVARAFGPIMVLWFAALALSGAISVSSHPGILAAISPHHAISFLMHNGLPGFFVLSEVILCATGGEALYADMGHLG
RKPVKRAWYFVFVALVINYLGQGAFIITHPDAKNILFGMLQYQAPLFYIPFLILTILATIIASQALISGVFSIVYQGINT
RMLPLLKVDYTSNQLKSQIYIGSVNWLLLCLVILIMLVFRKSANLAAAYGFAVTGTMVITGIMMTMIFSRTTKKWKVPLA
LFVTLVDVVFLVSNCNKLPHGGYWSLILASVPLAVILIWTRGQRGLYLALRPLDLETYLLSYEQIYKKGRIAGTGLFFVK
EWNIIPPYLVHCTIRSNIVYERNVLISIVRTDEPFGVESVLECGIGTGLDGFMIKAGYMEIFDIELLLKQNGIQEKVIFY
GIEDIATTNPIWRVFSVIKKLTPNFVQFNKVPAAKLQGVITRVEM
>Mature_605_residues
MKHGETDSYWGGIIKSMGLVFGDIGTSPIYTLTVIIALTKPTQDNILGIISLIVWTLIILVHLEYAVLAMSLSRKGEGGE
IVLREILVRMIKPGRQMAFVTFLTYLGVALLMGDGVITPAISILSAVEGTLLIPGLGGLSQNTLILIAGTIALFLFVFQY
KGTDKVARAFGPIMVLWFAALALSGAISVSSHPGILAAISPHHAISFLMHNGLPGFFVLSEVILCATGGEALYADMGHLG
RKPVKRAWYFVFVALVINYLGQGAFIITHPDAKNILFGMLQYQAPLFYIPFLILTILATIIASQALISGVFSIVYQGINT
RMLPLLKVDYTSNQLKSQIYIGSVNWLLLCLVILIMLVFRKSANLAAAYGFAVTGTMVITGIMMTMIFSRTTKKWKVPLA
LFVTLVDVVFLVSNCNKLPHGGYWSLILASVPLAVILIWTRGQRGLYLALRPLDLETYLLSYEQIYKKGRIAGTGLFFVK
EWNIIPPYLVHCTIRSNIVYERNVLISIVRTDEPFGVESVLECGIGTGLDGFMIKAGYMEIFDIELLLKQNGIQEKVIFY
GIEDIATTNPIWRVFSVIKKLTPNFVQFNKVPAAKLQGVITRVEM

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=560, Percent_Identity=35.7142857142857, Blast_Score=285, Evalue=8e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_PELPD (A1ALM1)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900299.1
- STRING:   A1ALM1
- GeneID:   4572131
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0610
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   IMMTMIF
- PhylomeDB:   A1ALM1
- ProtClustDB:   CLSK900490
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 66603; Mature: 66603

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2113ddcc)-; HASH(0x22ed5fb8)-; HASH(0x22fab104)-; HASH(0x22f9cc80)-; HASH(0x214d2cb4)-; HASH(0x22be90b4)-; HASH(0x22face98)-; HASH(0x2277e6d0)-; HASH(0x21414be8)-; HASH(0x21920638)-; HASH(0x22f9f704)-; HASH(0x22fa2ecc)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHGETDSYWGGIIKSMGLVFGDIGTSPIYTLTVIIALTKPTQDNILGIISLIVWTLIIL
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
VHLEYAVLAMSLSRKGEGGEIVLREILVRMIKPGRQMAFVTFLTYLGVALLMGDGVITPA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
ISILSAVEGTLLIPGLGGLSQNTLILIAGTIALFLFVFQYKGTDKVARAFGPIMVLWFAA
HHHHHHCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LALSGAISVSSHPGILAAISPHHAISFLMHNGLPGFFVLSEVILCATGGEALYADMGHLG
HHHHCCEEECCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
RKPVKRAWYFVFVALVINYLGQGAFIITHPDAKNILFGMLQYQAPLFYIPFLILTILATI
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IASQALISGVFSIVYQGINTRMLPLLKVDYTSNQLKSQIYIGSVNWLLLCLVILIMLVFR
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHCEEEEECHHHHHHHHHHHHHHHHC
KSANLAAAYGFAVTGTMVITGIMMTMIFSRTTKKWKVPLALFVTLVDVVFLVSNCNKLPH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GGYWSLILASVPLAVILIWTRGQRGLYLALRPLDLETYLLSYEQIYKKGRIAGTGLFFVK
CCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEECEEEEEE
EWNIIPPYLVHCTIRSNIVYERNVLISIVRTDEPFGVESVLECGIGTGLDGFMIKAGYME
ECCCCCCEEEEEEEECCEEEECCEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCHH
IFDIELLLKQNGIQEKVIFYGIEDIATTNPIWRVFSVIKKLTPNFVQFNKVPAAKLQGVI
HHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHH
TRVEM
HHCCH
>Mature Secondary Structure
MKHGETDSYWGGIIKSMGLVFGDIGTSPIYTLTVIIALTKPTQDNILGIISLIVWTLIIL
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
VHLEYAVLAMSLSRKGEGGEIVLREILVRMIKPGRQMAFVTFLTYLGVALLMGDGVITPA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
ISILSAVEGTLLIPGLGGLSQNTLILIAGTIALFLFVFQYKGTDKVARAFGPIMVLWFAA
HHHHHHCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LALSGAISVSSHPGILAAISPHHAISFLMHNGLPGFFVLSEVILCATGGEALYADMGHLG
HHHHCCEEECCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
RKPVKRAWYFVFVALVINYLGQGAFIITHPDAKNILFGMLQYQAPLFYIPFLILTILATI
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IASQALISGVFSIVYQGINTRMLPLLKVDYTSNQLKSQIYIGSVNWLLLCLVILIMLVFR
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHCEEEEECHHHHHHHHHHHHHHHHC
KSANLAAAYGFAVTGTMVITGIMMTMIFSRTTKKWKVPLALFVTLVDVVFLVSNCNKLPH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GGYWSLILASVPLAVILIWTRGQRGLYLALRPLDLETYLLSYEQIYKKGRIAGTGLFFVK
CCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEECEEEEEE
EWNIIPPYLVHCTIRSNIVYERNVLISIVRTDEPFGVESVLECGIGTGLDGFMIKAGYME
ECCCCCCEEEEEEEECCEEEECCEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCHH
IFDIELLLKQNGIQEKVIFYGIEDIATTNPIWRVFSVIKKLTPNFVQFNKVPAAKLQGVI
HHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHH
TRVEM
HHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA