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The map label for this gene is dtd

Identifier: 118578935

GI number: 118578935

Start: 516603

End: 517040

Strand: Reverse

Name: dtd

Synonym: Ppro_0496

Alternate gene names: 118578935

Gene position: 517040-516603 (Counterclockwise)

Preceding gene: 118578938

Following gene: 118578932

Centisome position: 12.9

GC content: 64.16

Gene sequence:

>438_bases
ATGAAAGCGGTGATCCAGCGGGTCTGTTCAGCCAGCGTGGTGGTGGAGGGAGAGGTTGTGGGGGAAATCGGCCAAGGCAT
CCTGGTGCTCTTGGGGGTGGAGAAGGGGGATGACGAGGCAAAGGCCTCCTGGCTGGCGGAGAAGATCATCTCCTTGCGCA
TCTTCGGCGACGACAGCGACAAGATGAACCTGTCGCTACGGGACGTGGGGGGAAGCCTGCTGGCCGTCTCCCAGTTCACC
TTGGCGGGCAATTGCGCCAAGGGGAGGCGCCCCTCATTCGACAGTGCCGCCCCGCCGGAGGAGGGCAGGCGGCTGTACGA
CCATTTCGTGCAGGCGGTCAGGGCAAAGGGCGTGGCGACCGCCACAGGCATCTTCCAGGCCGACATGCGGGTCAGCCTGG
TCAACGACGGGCCGGTGACCTTTATCCTGGAGAGATAG

Upstream 100 bases:

>100_bases
GGCAAGTGCTCCGTCCCGTCCAGAGACCGCTGGAGATGGCTGACCGGAGGGCACACACCCGGCCGGCAGGGGAACAACAC
ATGAAACCAGGAGGTGTTCG

Downstream 100 bases:

>100_bases
CCAAGAGATGGCACAGGGCACAGGCAGGGGAAGCGTTAGCCGTAAACGTTCACGCCCACTGCCATCCGCGAACCCGTGGA
ATCATCCCTGCCGGTTGACG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKAVIQRVCSASVVVEGEVVGEIGQGILVLLGVEKGDDEAKASWLAEKIISLRIFGDDSDKMNLSLRDVGGSLLAVSQFT
LAGNCAKGRRPSFDSAAPPEEGRRLYDHFVQAVRAKGVATATGIFQADMRVSLVNDGPVTFILER

Sequences:

>Translated_145_residues
MKAVIQRVCSASVVVEGEVVGEIGQGILVLLGVEKGDDEAKASWLAEKIISLRIFGDDSDKMNLSLRDVGGSLLAVSQFT
LAGNCAKGRRPSFDSAAPPEEGRRLYDHFVQAVRAKGVATATGIFQADMRVSLVNDGPVTFILER
>Mature_145_residues
MKAVIQRVCSASVVVEGEVVGEIGQGILVLLGVEKGDDEAKASWLAEKIISLRIFGDDSDKMNLSLRDVGGSLLAVSQFT
LAGNCAKGRRPSFDSAAPPEEGRRLYDHFVQAVRAKGVATATGIFQADMRVSLVNDGPVTFILER

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=42.5675675675676, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=59.0277777777778, Blast_Score=169, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI115533292, Length=147, Percent_Identity=40.8163265306122, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319982, Length=147, Percent_Identity=38.0952380952381, Blast_Score=102, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=40.4109589041096, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_PELPD (A1ALA7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900185.1
- ProteinModelPortal:   A1ALA7
- SMR:   A1ALA7
- STRING:   A1ALA7
- GeneID:   4572920
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0496
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   A1ALA7
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15477; Mature: 15477

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVIQRVCSASVVVEGEVVGEIGQGILVLLGVEKGDDEAKASWLAEKIISLRIFGDDSD
CHHHHHHHHCCEEEEECHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEECCCCC
KMNLSLRDVGGSLLAVSQFTLAGNCAKGRRPSFDSAAPPEEGRRLYDHFVQAVRAKGVAT
CEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ATGIFQADMRVSLVNDGPVTFILER
EHHEEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MKAVIQRVCSASVVVEGEVVGEIGQGILVLLGVEKGDDEAKASWLAEKIISLRIFGDDSD
CHHHHHHHHCCEEEEECHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEECCCCC
KMNLSLRDVGGSLLAVSQFTLAGNCAKGRRPSFDSAAPPEEGRRLYDHFVQAVRAKGVAT
CEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ATGIFQADMRVSLVNDGPVTFILER
EHHEEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA