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The map label for this gene is radA [H]

Identifier: 118578864

GI number: 118578864

Start: 442049

End: 443395

Strand: Reverse

Name: radA [H]

Synonym: Ppro_0422

Alternate gene names: 118578864

Gene position: 443395-442049 (Counterclockwise)

Preceding gene: 118578866

Following gene: 118578863

Centisome position: 11.06

GC content: 63.7

Gene sequence:

>1347_bases
ATGAAGGTGAAAACCGTTTTTTCCTGCCAGAACTGCGGCTGCCAGTCCCCCAAGTGGCTGGGCAAGTGCCCCGATTGCGG
TTCCTGGAACAGCATGACCGAGGAGGCCTCCGCCCCGCGCCAGGCCGCACCGTCCGGCGAGCGTTCCAAGCCGATACCGA
TCTGCGACGTGCCGGCCCAGTCGGAAACCAGGATCGCATCCGACTTGGGAGAATTGGACCGAGTGCTGGGAGGAGGCATC
GTGCCCGGCTCGCTGGTGCTGATCGGCGGCGACCCGGGCATCGGCAAGTCGACCCTGCTGCTTCAGGCTATGCACAACCT
GGCCGCTTCAGCCGGGCAGGTATTGTACGTTTCGGGCGAGGAGTCAGCCTCCCAGACCCGCCTGCGGGGCGAACGCCTGG
GTGCGTCCCACAAGCGACTGCTCATCCTGGCGGAGAACTCTCTGGAGGCGATCATTGCCCATGCCACAGCCCTCAAACCA
ACGGTCATGGTGATCGACTCCATCCAGACCGTCTGGACCTCGGCTCTGGAATCGGCGCCCGGCAGCGTCAGCCAGGTGCG
GGAATCCGCCGGCAAGCTGATGCTGCTGGCCAAGGGCCTGGACATACCGGTATTCATTGTCGGCCACGTCACAAAGGACG
GCGCCATCGCCGGGCCGCGGGTGCTAGAGCATATCGTTGATACGGTGCTCTATTTCGAAGGGGACGGCAGCCACCCCTTC
CGCATCCTGCGGGCGGTGAAGAACCGCTTCGGCTCGACCAACGAGATCGGTGTCTTTGAAATGAAGCGGGAAGGGCTGAT
CGGCGTGGAGAATCCGTCGGAACTGTTCCTCTCCGAGCGCCCCCTGGGCGCACCGGGATCGGTGGTAACAGCATCCCTGG
AGGGGAGTCGCCCGCTGCTGGTGGAACTTCAGGCTCTGGTCACCAAGACATCCTACCCAGTCCCGCGGCGAACAACCATC
GGGGTCGACCACAACCGCCTTGCGCTCCTTGTGGCGGTGCTGGAGAAAAAGGTCGGCCTGCATCTGGCCGGACTGGATAT
TTTCTTAAACGCGGCAGGCGGCGTGCGCCTCAATGAACCGGCCGCCGACCTGGCCATGATCATGGCGGTTGCCTCCAGCC
ACCTGGACAGGATCATCCCGCCCCAGACCGTCGTACTGGGCGAGGTGGGGCTGACGGGAGAGGTGCGCGCCATCACCCAA
CCGGAGCAGCGCATCGCCGAAGCAGAGAAGCTCGGTTTTCAGTCCTGCATCATCCCCGCCGGCAACCTGAGGCGGCTCAC
GAAAAGCAAGATCAGGCTTGAGGGGGTTGCCTCGGTGGATGAGGCCATGCAGTTGCTTATGCAGTGA

Upstream 100 bases:

>100_bases
TGATATACCGAAAACCGGCTTTGTCAATTCCCGTGAGCGGCGTAACCGACGCAAACCCGCCTGTTTTCAGAATGTTGCCG
CCGGGAGCAGAGGAGTGGAC

Downstream 100 bases:

>100_bases
TTCTATTTTTTTCTGGACTTGGCCAATGGTTATCTTTAGACTCTTTTTTTTAAAGAGAAAGATCAGGAGCAGGCAATGGA
AGCTGAAAAACTGGAGTATT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKVKTVFSCQNCGCQSPKWLGKCPDCGSWNSMTEEASAPRQAAPSGERSKPIPICDVPAQSETRIASDLGELDRVLGGGI
VPGSLVLIGGDPGIGKSTLLLQAMHNLAASAGQVLYVSGEESASQTRLRGERLGASHKRLLILAENSLEAIIAHATALKP
TVMVIDSIQTVWTSALESAPGSVSQVRESAGKLMLLAKGLDIPVFIVGHVTKDGAIAGPRVLEHIVDTVLYFEGDGSHPF
RILRAVKNRFGSTNEIGVFEMKREGLIGVENPSELFLSERPLGAPGSVVTASLEGSRPLLVELQALVTKTSYPVPRRTTI
GVDHNRLALLVAVLEKKVGLHLAGLDIFLNAAGGVRLNEPAADLAMIMAVASSHLDRIIPPQTVVLGEVGLTGEVRAITQ
PEQRIAEAEKLGFQSCIIPAGNLRRLTKSKIRLEGVASVDEAMQLLMQ

Sequences:

>Translated_448_residues
MKVKTVFSCQNCGCQSPKWLGKCPDCGSWNSMTEEASAPRQAAPSGERSKPIPICDVPAQSETRIASDLGELDRVLGGGI
VPGSLVLIGGDPGIGKSTLLLQAMHNLAASAGQVLYVSGEESASQTRLRGERLGASHKRLLILAENSLEAIIAHATALKP
TVMVIDSIQTVWTSALESAPGSVSQVRESAGKLMLLAKGLDIPVFIVGHVTKDGAIAGPRVLEHIVDTVLYFEGDGSHPF
RILRAVKNRFGSTNEIGVFEMKREGLIGVENPSELFLSERPLGAPGSVVTASLEGSRPLLVELQALVTKTSYPVPRRTTI
GVDHNRLALLVAVLEKKVGLHLAGLDIFLNAAGGVRLNEPAADLAMIMAVASSHLDRIIPPQTVVLGEVGLTGEVRAITQ
PEQRIAEAEKLGFQSCIIPAGNLRRLTKSKIRLEGVASVDEAMQLLMQ
>Mature_448_residues
MKVKTVFSCQNCGCQSPKWLGKCPDCGSWNSMTEEASAPRQAAPSGERSKPIPICDVPAQSETRIASDLGELDRVLGGGI
VPGSLVLIGGDPGIGKSTLLLQAMHNLAASAGQVLYVSGEESASQTRLRGERLGASHKRLLILAENSLEAIIAHATALKP
TVMVIDSIQTVWTSALESAPGSVSQVRESAGKLMLLAKGLDIPVFIVGHVTKDGAIAGPRVLEHIVDTVLYFEGDGSHPF
RILRAVKNRFGSTNEIGVFEMKREGLIGVENPSELFLSERPLGAPGSVVTASLEGSRPLLVELQALVTKTSYPVPRRTTI
GVDHNRLALLVAVLEKKVGLHLAGLDIFLNAAGGVRLNEPAADLAMIMAVASSHLDRIIPPQTVVLGEVGLTGEVRAITQ
PEQRIAEAEKLGFQSCIIPAGNLRRLTKSKIRLEGVASVDEAMQLLMQ

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=453, Percent_Identity=44.3708609271523, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 47531; Mature: 47531

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKTVFSCQNCGCQSPKWLGKCPDCGSWNSMTEEASAPRQAAPSGERSKPIPICDVPAQ
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCCCC
SETRIASDLGELDRVLGGGIVPGSLVLIGGDPGIGKSTLLLQAMHNLAASAGQVLYVSGE
CHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
ESASQTRLRGERLGASHKRLLILAENSLEAIIAHATALKPTVMVIDSIQTVWTSALESAP
CCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCC
GSVSQVRESAGKLMLLAKGLDIPVFIVGHVTKDGAIAGPRVLEHIVDTVLYFEGDGSHPF
CHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHEEEECCCCCHH
RILRAVKNRFGSTNEIGVFEMKREGLIGVENPSELFLSERPLGAPGSVVTASLEGSRPLL
HHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCCHH
VELQALVTKTSYPVPRRTTIGVDHNRLALLVAVLEKKVGLHLAGLDIFLNAAGGVRLNEP
HHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEECCC
AADLAMIMAVASSHLDRIIPPQTVVLGEVGLTGEVRAITQPEQRIAEAEKLGFQSCIIPA
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHHCCCHHEECCC
GNLRRLTKSKIRLEGVASVDEAMQLLMQ
CHHHHHHHHHHHEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVKTVFSCQNCGCQSPKWLGKCPDCGSWNSMTEEASAPRQAAPSGERSKPIPICDVPAQ
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCCCC
SETRIASDLGELDRVLGGGIVPGSLVLIGGDPGIGKSTLLLQAMHNLAASAGQVLYVSGE
CHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
ESASQTRLRGERLGASHKRLLILAENSLEAIIAHATALKPTVMVIDSIQTVWTSALESAP
CCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCC
GSVSQVRESAGKLMLLAKGLDIPVFIVGHVTKDGAIAGPRVLEHIVDTVLYFEGDGSHPF
CHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHEEEECCCCCHH
RILRAVKNRFGSTNEIGVFEMKREGLIGVENPSELFLSERPLGAPGSVVTASLEGSRPLL
HHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCCHH
VELQALVTKTSYPVPRRTTIGVDHNRLALLVAVLEKKVGLHLAGLDIFLNAAGGVRLNEP
HHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEECCC
AADLAMIMAVASSHLDRIIPPQTVVLGEVGLTGEVRAITQPEQRIAEAEKLGFQSCIIPA
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHHCCCHHEECCC
GNLRRLTKSKIRLEGVASVDEAMQLLMQ
CHHHHHHHHHHHEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]