Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 118578743

GI number: 118578743

Start: 299147

End: 300856

Strand: Reverse

Name: dnaX [H]

Synonym: Ppro_0301

Alternate gene names: 118578743

Gene position: 300856-299147 (Counterclockwise)

Preceding gene: 118578745

Following gene: 118578742

Centisome position: 7.51

GC content: 63.1

Gene sequence:

>1710_bases
TTGTCCAACGGCACGCACTATGAAGTCCTGGCCAGGAAATACCGTCCCCAGACCCTTTCGGAACTGACCGGCCAGGAACA
CGTCAGCCGCACCCTTCAGAACGCAATCGATTCCGGCCGCGTGGCCCACGCCTTCCTGTTCAGCGGAGCCCGCGGTGTCG
GCAAGACCAGCACGGCCCGCATCCTGGCCAAGGCCCTCAACTGCGAACGGGGCGTCTCCACCGAACCCTGCAACACCTGC
CCCTTGTGCATCGAAATCACCAAGGGCACATCCACCGACGTCTTCGAGATAGACGGCGCGTCCAATACCGGCGTGGACGA
CATCCGCGAACTGCGCGACAACGCCAAGTATCTCCCTTCCCACAGCCGCTACAAGATCTTCATCATCGATGAAGTCCACA
TGCTCTCCACCAACGCCTTCAACGCCCTGCTGAAGACGCTTGAGGAACCTCCCGAGCACGTCAAGTTCATCTTTGCCACC
ACCGAACCGCACAAACTCCCCATCACCATCCTGTCCCGCTGCCAGCGCTTCGACTTCAAGCGCATCCCGCTGGCCAAGAT
CATCGGCCGCCTGCGCCAGATCGCCGACGCCGAGGGGATCAGCATCAACGATTCGGCCTTGGCCCTGATCGCCCGCAAGG
GGGACGGCAGCATGCGCGACTCCCTGACCGCCTTCGACCAGGTGCTGGCCTGCTGCGGCAGCAACGTAAGCGACGAAGAT
ACGGCCACCCTGATCGGCGCCGTTGACCGCAGGCTGCTGGCGAACATCTCCGCAGCCATCTTCGCAGCCGACACCCAGGC
AGTGCTGGCAGGCATCAGACAGGTGGACGAGGTGGGATACAACCTGCGCCAGTTCTGCCAGGAGCTGATCGAGCAGCTCC
GCAACCTGATGGTGGTAAGCTCGGTCCGGAAACCGGAAGAGATCCTGGACCTGTCAGCGCCGGAACTGGACGATCTGCGT
CGCCAGGCAAACGGATTCTCCAGCCAGGATATCCAGCGCCGGCTGACGCTCCTGATCAGAGCCGACGGCGAGATGGCCCA
CGCCAGCTTCCCCAGGCTGGTTCTGGAGATCGCCCTGCTGAAGGCGGCCACCCTGGAGCCGGTGATACCGATCCAGGAAT
TATTGGAAAAACTACAGGCGCTTGAGAGTGGCACCACGTGGACAACACCCTCTCCCCGGGACAGCGTCCGCATGCCGCCG
GTCGGGGAGCAGCGCCAACAACAACCAACCGAGAGACCACAGCAGCAACCTGCGGCCGCTTCCGTACCTCCCGAACCTTC
CGCCCCCCCAGCGCCGGAAAAACTGAGAGACACTGCCCTTCCCTCCTGGGAGCGCTTCGTCAGCTTCGCCAGCGAAAAGG
ACCCGGCCCTCGGCTCGGTGCTGGAACACGGCAGCCCCATCCGACAGGAGGCTGGTCTGATGGAGATCGGCTTCCCGGCC
GGCAGCTACTATCTGGCAAACATCCAGGATACCGACTCCATCGCCCAACTCAGGGCGCTGGCCCGGGAATTCACCGGCCA
GGAGACCAATATCCGCATACAGTCCATCGCCCGCGAGACAGCCGGTGCCCCCCCCTCGCTGGCGGAAAAAAAAAAGAGCG
ATCGTGAACAGCGCCAGCAGGAGCTGAAACAGGAGGTCAACGAGCACCCGCTGGTACGGGAGGCCCTACGCATCTTCGGC
GGAACCATCACCGAGATCCGCGAGGCCTGA

Upstream 100 bases:

>100_bases
CCCATCCCAGTCCTAACGCCACGTGCCACCGGCATGAATTCACCCCATACTTTCACGCACGGGATGTCGGGGCGACAGAA
GACCTGTGAGGTTCGATCTC

Downstream 100 bases:

>100_bases
GACGGCTCAGGCACCCGCACCCAAACAGAATCAGTAAAGCAGATTCACCTTGCAAAAAGCAAACAGCGTTAAAGTGGTAT
GACCAATGTCGCGACAAACG

Product: DNA polymerase III subunits gamma/tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSNGTHYEVLARKYRPQTLSELTGQEHVSRTLQNAIDSGRVAHAFLFSGARGVGKTSTARILAKALNCERGVSTEPCNTC
PLCIEITKGTSTDVFEIDGASNTGVDDIRELRDNAKYLPSHSRYKIFIIDEVHMLSTNAFNALLKTLEEPPEHVKFIFAT
TEPHKLPITILSRCQRFDFKRIPLAKIIGRLRQIADAEGISINDSALALIARKGDGSMRDSLTAFDQVLACCGSNVSDED
TATLIGAVDRRLLANISAAIFAADTQAVLAGIRQVDEVGYNLRQFCQELIEQLRNLMVVSSVRKPEEILDLSAPELDDLR
RQANGFSSQDIQRRLTLLIRADGEMAHASFPRLVLEIALLKAATLEPVIPIQELLEKLQALESGTTWTTPSPRDSVRMPP
VGEQRQQQPTERPQQQPAAASVPPEPSAPPAPEKLRDTALPSWERFVSFASEKDPALGSVLEHGSPIRQEAGLMEIGFPA
GSYYLANIQDTDSIAQLRALAREFTGQETNIRIQSIARETAGAPPSLAEKKKSDREQRQQELKQEVNEHPLVREALRIFG
GTITEIREA

Sequences:

>Translated_569_residues
MSNGTHYEVLARKYRPQTLSELTGQEHVSRTLQNAIDSGRVAHAFLFSGARGVGKTSTARILAKALNCERGVSTEPCNTC
PLCIEITKGTSTDVFEIDGASNTGVDDIRELRDNAKYLPSHSRYKIFIIDEVHMLSTNAFNALLKTLEEPPEHVKFIFAT
TEPHKLPITILSRCQRFDFKRIPLAKIIGRLRQIADAEGISINDSALALIARKGDGSMRDSLTAFDQVLACCGSNVSDED
TATLIGAVDRRLLANISAAIFAADTQAVLAGIRQVDEVGYNLRQFCQELIEQLRNLMVVSSVRKPEEILDLSAPELDDLR
RQANGFSSQDIQRRLTLLIRADGEMAHASFPRLVLEIALLKAATLEPVIPIQELLEKLQALESGTTWTTPSPRDSVRMPP
VGEQRQQQPTERPQQQPAAASVPPEPSAPPAPEKLRDTALPSWERFVSFASEKDPALGSVLEHGSPIRQEAGLMEIGFPA
GSYYLANIQDTDSIAQLRALAREFTGQETNIRIQSIARETAGAPPSLAEKKKSDREQRQQELKQEVNEHPLVREALRIFG
GTITEIREA
>Mature_568_residues
SNGTHYEVLARKYRPQTLSELTGQEHVSRTLQNAIDSGRVAHAFLFSGARGVGKTSTARILAKALNCERGVSTEPCNTCP
LCIEITKGTSTDVFEIDGASNTGVDDIRELRDNAKYLPSHSRYKIFIIDEVHMLSTNAFNALLKTLEEPPEHVKFIFATT
EPHKLPITILSRCQRFDFKRIPLAKIIGRLRQIADAEGISINDSALALIARKGDGSMRDSLTAFDQVLACCGSNVSDEDT
ATLIGAVDRRLLANISAAIFAADTQAVLAGIRQVDEVGYNLRQFCQELIEQLRNLMVVSSVRKPEEILDLSAPELDDLRR
QANGFSSQDIQRRLTLLIRADGEMAHASFPRLVLEIALLKAATLEPVIPIQELLEKLQALESGTTWTTPSPRDSVRMPPV
GEQRQQQPTERPQQQPAAASVPPEPSAPPAPEKLRDTALPSWERFVSFASEKDPALGSVLEHGSPIRQEAGLMEIGFPAG
SYYLANIQDTDSIAQLRALAREFTGQETNIRIQSIARETAGAPPSLAEKKKSDREQRQQELKQEVNEHPLVREALRIFGG
TITEIREA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=294, Percent_Identity=25.1700680272109, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI194306571, Length=297, Percent_Identity=24.9158249158249, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI194306567, Length=297, Percent_Identity=24.9158249158249, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI4506491, Length=298, Percent_Identity=25.1677852348993, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI31881687, Length=298, Percent_Identity=25.1677852348993, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI31563534, Length=232, Percent_Identity=25.4310344827586, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1786676, Length=369, Percent_Identity=43.360433604336, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1787341, Length=150, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554730, Length=295, Percent_Identity=26.1016949152542, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17541988, Length=215, Percent_Identity=26.046511627907, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71986063, Length=234, Percent_Identity=27.3504273504274, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324039, Length=230, Percent_Identity=29.5652173913043, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324478, Length=225, Percent_Identity=25.7777777777778, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI18859927, Length=291, Percent_Identity=23.0240549828179, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19921076, Length=225, Percent_Identity=27.1111111111111, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647857, Length=272, Percent_Identity=23.1617647058824, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 62750; Mature: 62619

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGTHYEVLARKYRPQTLSELTGQEHVSRTLQNAIDSGRVAHAFLFSGARGVGKTSTAR
CCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHH
ILAKALNCERGVSTEPCNTCPLCIEITKGTSTDVFEIDGASNTGVDDIRELRDNAKYLPS
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCC
HSRYKIFIIDEVHMLSTNAFNALLKTLEEPPEHVKFIFATTEPHKLPITILSRCQRFDFK
CCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
RIPLAKIIGRLRQIADAEGISINDSALALIARKGDGSMRDSLTAFDQVLACCGSNVSDED
CCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHH
TATLIGAVDRRLLANISAAIFAADTQAVLAGIRQVDEVGYNLRQFCQELIEQLRNLMVVS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
SVRKPEEILDLSAPELDDLRRQANGFSSQDIQRRLTLLIRADGEMAHASFPRLVLEIALL
HCCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
KAATLEPVIPIQELLEKLQALESGTTWTTPSPRDSVRMPPVGEQRQQQPTERPQQQPAAA
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCC
SVPPEPSAPPAPEKLRDTALPSWERFVSFASEKDPALGSVLEHGSPIRQEAGLMEIGFPA
CCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHCCCEEECCCC
GSYYLANIQDTDSIAQLRALAREFTGQETNIRIQSIARETAGAPPSLAEKKKSDREQRQQ
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ELKQEVNEHPLVREALRIFGGTITEIREA
HHHHHHCCCHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
SNGTHYEVLARKYRPQTLSELTGQEHVSRTLQNAIDSGRVAHAFLFSGARGVGKTSTAR
CCCCHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHH
ILAKALNCERGVSTEPCNTCPLCIEITKGTSTDVFEIDGASNTGVDDIRELRDNAKYLPS
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCC
HSRYKIFIIDEVHMLSTNAFNALLKTLEEPPEHVKFIFATTEPHKLPITILSRCQRFDFK
CCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
RIPLAKIIGRLRQIADAEGISINDSALALIARKGDGSMRDSLTAFDQVLACCGSNVSDED
CCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHH
TATLIGAVDRRLLANISAAIFAADTQAVLAGIRQVDEVGYNLRQFCQELIEQLRNLMVVS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
SVRKPEEILDLSAPELDDLRRQANGFSSQDIQRRLTLLIRADGEMAHASFPRLVLEIALL
HCCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
KAATLEPVIPIQELLEKLQALESGTTWTTPSPRDSVRMPPVGEQRQQQPTERPQQQPAAA
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCC
SVPPEPSAPPAPEKLRDTALPSWERFVSFASEKDPALGSVLEHGSPIRQEAGLMEIGFPA
CCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHCCCEEECCCC
GSYYLANIQDTDSIAQLRALAREFTGQETNIRIQSIARETAGAPPSLAEKKKSDREQRQQ
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ELKQEVNEHPLVREALRIFGGTITEIREA
HHHHHHCCCHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]