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The map label for this gene is engD [H]

Identifier: 118480503

GI number: 118480503

Start: 5244697

End: 5245806

Strand: Reverse

Name: engD [H]

Synonym: BALH_4983

Alternate gene names: 118480503

Gene position: 5245806-5244697 (Counterclockwise)

Preceding gene: 118480504

Following gene: 118480502

Centisome position: 99.79

GC content: 37.21

Gene sequence:

>1110_bases
GTGAAAAATATGGGATTAACGGCTGGGATTGTTGGATTACCTAACGTAGGGAAGTCCACTTTATTTAATGCAATTACACA
AGCAGGAGCAGAATCTGCGAACTATCCATTCTGTACAATTGATCCAAACGTAGGAATTGTAGAAGTACCAGATGAGCGTT
TAAATAAATTAACGGAATTAGTAGAACCGAAAAAAACTGTTCCGACTGTATTTGAGTTTACTGATATTGCAGGTATCGTA
AAAGGTGCGAGTAAAGGTGAAGGTTTAGGAAATAAATTCTTATCTCACATTCGCCAAGTAGATGCAATTTGCCAAGTTGT
TCGTTGTTTTGAAGACGAAAATATTACGCATGTTTCAGGTAAAGTAGATCCAATTGATGATATTGAAACAATCAACTTAG
AGCTAATCTTAGCAGACTTAGAATCTGTTGATAAACGTATCGAACGTGTTGCGAAATTAGCAAGACAAAAGGATAAAGAA
GCAGTATATGAGCATGAAATTTTAGTACGTTTAAAAGAAGCTTTTGAAGAGGGGAAACCAGCTCGTACTGTTGAATTTAC
AGAAGAGCAAATGAAGATTGTTAAAGGTCTTCATTTACTGACAACGAAAGAAATGTTATACGTAGCAAACGTAAGCGAGG
ACGATGTTATCGATCCTTCTGAAAACAAATACGTACAAATGGTAAAAGAATTTGCTGCAAATGAAAATTCTCAAGTAATC
GTTGTATGTGCAAAAATCGAATCAGAAATTGCTGAGCTAGACGAAGAAGAGAAAAAAGTCTTCCTTGAGGAACTGGGCAT
TGAGGAATCTGGTTTAGATCAATTAATTCGTGCTGCATATGATTTATTAGGACTTGCTACGTACTTCACAGCAGGTGTGC
AAGAAGTACGCGCATGGACGTTCAAACAAGGTATGAAAGCACCACAATGTGCCGGCGTAATTCATACAGACTTTGAGCGT
GGATTTATTCGTGCAGAAACAGTTTCTTACGAAGACTTAATGACAAACGGTTCTATGACAGCTGCAAAAGAAGCTGGTAA
AGTTCGTTTAGAAGGAAAAGAGTATATCGTAAAGGACGGAGACGTTATGCATTTCCGTTTCAACGTTTAA

Upstream 100 bases:

>100_bases
AGTAACAGTTGCAGTGGGTAGCTGTTACTTTTTTTCGTTTGGAGGAAACTTGTCATTTTTTTCGTTACTATCTATAATGA
TGAAAGATTGAGACATAGGA

Downstream 100 bases:

>100_bases
TTTAATATTTCCTAGGAAAAATAAAGATATGAACTTGGCAAATATATTATGTGTTTGCCAAGTTTTTTATGTATGGGTGA
GTTGATTCATCTAACTTACT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKNMGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLNKLTELVEPKKTVPTVFEFTDIAGIV
KGASKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKE
AVYEHEILVRLKEAFEEGKPARTVEFTEEQMKIVKGLHLLTTKEMLYVANVSEDDVIDPSENKYVQMVKEFAANENSQVI
VVCAKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKQGMKAPQCAGVIHTDFER
GFIRAETVSYEDLMTNGSMTAAKEAGKVRLEGKEYIVKDGDVMHFRFNV

Sequences:

>Translated_369_residues
MKNMGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLNKLTELVEPKKTVPTVFEFTDIAGIV
KGASKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKE
AVYEHEILVRLKEAFEEGKPARTVEFTEEQMKIVKGLHLLTTKEMLYVANVSEDDVIDPSENKYVQMVKEFAANENSQVI
VVCAKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKQGMKAPQCAGVIHTDFER
GFIRAETVSYEDLMTNGSMTAAKEAGKVRLEGKEYIVKDGDVMHFRFNV
>Mature_369_residues
MKNMGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLNKLTELVEPKKTVPTVFEFTDIAGIV
KGASKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSGKVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKE
AVYEHEILVRLKEAFEEGKPARTVEFTEEQMKIVKGLHLLTTKEMLYVANVSEDDVIDPSENKYVQMVKEFAANENSQVI
VVCAKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWTFKQGMKAPQCAGVIHTDFER
GFIRAETVSYEDLMTNGSMTAAKEAGKVRLEGKEYIVKDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=45.2574525745258, Blast_Score=318, Evalue=7e-87,
Organism=Homo sapiens, GI58761502, Length=228, Percent_Identity=39.4736842105263, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI24308117, Length=111, Percent_Identity=36.9369369369369, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=57.6502732240437, Blast_Score=436, Evalue=1e-124,
Organism=Escherichia coli, GI1789574, Length=134, Percent_Identity=32.089552238806, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.896174863388, Blast_Score=311, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=41.9354838709677, Blast_Score=267, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6321773, Length=387, Percent_Identity=38.2428940568475, Blast_Score=232, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6321649, Length=160, Percent_Identity=36.875, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6321962, Length=147, Percent_Identity=27.2108843537415, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640873, Length=370, Percent_Identity=42.7027027027027, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24640877, Length=370, Percent_Identity=42.7027027027027, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24640875, Length=370, Percent_Identity=42.7027027027027, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24640879, Length=329, Percent_Identity=40.4255319148936, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24585318, Length=164, Percent_Identity=31.0975609756098, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 41070; Mature: 41070

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLNKLTEL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHH
VEPKKTVPTVFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSG
HCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
KVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKEAVYEHEILVRLKEAFEEGKP
CCCCCCCCEEEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ARTVEFTEEQMKIVKGLHLLTTKEMLYVANVSEDDVIDPSENKYVQMVKEFAANENSQVI
CCEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE
VVCAKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWT
EEEEHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKQGMKAPQCAGVIHTDFERGFIRAETVSYEDLMTNGSMTAAKEAGKVRLEGKEYIVKDG
HHHCCCCCCCCCCEECHHHCCEEEEECCCHHHHHCCCCCHHHHHCCCEEECCCEEEEECC
DVMHFRFNV
CEEEEEECC
>Mature Secondary Structure
MKNMGLTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLNKLTEL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHH
VEPKKTVPTVFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICQVVRCFEDENITHVSG
HCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
KVDPIDDIETINLELILADLESVDKRIERVAKLARQKDKEAVYEHEILVRLKEAFEEGKP
CCCCCCCCEEEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ARTVEFTEEQMKIVKGLHLLTTKEMLYVANVSEDDVIDPSENKYVQMVKEFAANENSQVI
CCEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE
VVCAKIESEIAELDEEEKKVFLEELGIEESGLDQLIRAAYDLLGLATYFTAGVQEVRAWT
EEEEHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKQGMKAPQCAGVIHTDFERGFIRAETVSYEDLMTNGSMTAAKEAGKVRLEGKEYIVKDG
HHHCCCCCCCCCCEECHHHCCEEEEECCCHHHHHCCCCCHHHHHCCCEEECCCEEEEECC
DVMHFRFNV
CEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]