Click here to switch to the map view.

The map label for this gene is ykhA [H]

Identifier: 118480457

GI number: 118480457

Start: 5190706

End: 5191278

Strand: Direct

Name: ykhA [H]

Synonym: BALH_4929

Alternate gene names: 118480457

Gene position: 5190706-5191278 (Clockwise)

Preceding gene: 118480455

Following gene: 118480458

Centisome position: 98.74

GC content: 36.13

Gene sequence:

>573_bases
TTGTACTCCACTTACAATACATGTCATTCTGATCGAAAACAGAAAATAGGGGCTGACCATATGGAAAAGAAATTCATGCG
AGAATCTAAAGCAATTAAAACAACACGTGTTTTTCCAAATGATTTAAATAATCATCAAACACTTTTCGGAGGAAAATTAT
TAGCAGAAATTGATAGTATTGCTTCAATTGCAGCTGCAAGGCATAGTCGTAAACATTGCGTAACAGCATCTATCGATTCT
GTTGATTTTTTAACTCCCATTCACCAAGCAGATTCTGTTTGTTACGAAGCATTCGTATGTTATACAGGAAAATCTTCAAT
GGAAGTGTTCGTAAAAGTAATTGCAGAGAATTTATTAGCAGGAGAACGTAGAATAGCTGCAACATGTTTCATTACATTCG
TTGCATTAAAAGATGGAAAACCTTCTTCTGTTCCACAAGTACTACCTGAAACGGAAGAGGAACATTGGCTACACAAAACT
GGCGCTGAGCGTGCAGAAAGTAGAAAAAAAGGGCGTGTAAAAAGCAAAGAAATGGCTGAAGTTCTAACTTTAAGTAAACC
TTGGAGTATGTAG

Upstream 100 bases:

>100_bases
ATAAATTTTCTTTCAGTTACATGAATACAAATACAGAAGTTTTACTAATCCTCTTCTGGAATTCTTTACTTCATTAAATA
TCTATAGATTTTTAATATTT

Downstream 100 bases:

>100_bases
GCCTTCACCATTAAGACATCTTCTGAGCGAATAACGATCATGTATTCGCTCATTTTTTATAAACAATTTCCCGTCTTCAT
ACAACCATTCCTCCTTTTCA

Product: cytosolic long-chain acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MYSTYNTCHSDRKQKIGADHMEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDS
VDFLTPIHQADSVCYEAFVCYTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHKT
GAERAESRKKGRVKSKEMAEVLTLSKPWSM

Sequences:

>Translated_190_residues
MYSTYNTCHSDRKQKIGADHMEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDS
VDFLTPIHQADSVCYEAFVCYTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHKT
GAERAESRKKGRVKSKEMAEVLTLSKPWSM
>Mature_190_residues
MYSTYNTCHSDRKQKIGADHMEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDS
VDFLTPIHQADSVCYEAFVCYTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHKT
GAERAESRKKGRVKSKEMAEVLTLSKPWSM

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528284, Length=131, Percent_Identity=34.3511450381679, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32528286, Length=131, Percent_Identity=34.3511450381679, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI75709208, Length=131, Percent_Identity=34.3511450381679, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI32528282, Length=131, Percent_Identity=34.3511450381679, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI22165355, Length=132, Percent_Identity=35.6060606060606, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI22165400, Length=132, Percent_Identity=35.6060606060606, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI18640736, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 21322; Mature: 21322

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTYNTCHSDRKQKIGADHMEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSI
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASIAAARHSRKHCVTASIDSVDFLTPIHQADSVCYEAFVCYTGKSSMEVFVKVIAENLLA
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHKTGAERAESRKKGRVKSKEMAE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VLTLSKPWSM
HHHCCCCCCC
>Mature Secondary Structure
MYSTYNTCHSDRKQKIGADHMEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSI
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASIAAARHSRKHCVTASIDSVDFLTPIHQADSVCYEAFVCYTGKSSMEVFVKVIAENLLA
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHKTGAERAESRKKGRVKSKEMAE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VLTLSKPWSM
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]