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The map label for this gene is yfnB [H]

Identifier: 118480439

GI number: 118480439

Start: 5171699

End: 5172394

Strand: Reverse

Name: yfnB [H]

Synonym: BALH_4908

Alternate gene names: 118480439

Gene position: 5172394-5171699 (Counterclockwise)

Preceding gene: 118480441

Following gene: 118480438

Centisome position: 98.39

GC content: 33.33

Gene sequence:

>696_bases
ATGAAAAAATATAAAATACTATTATTTGATGTAGATGATACATTGTTAGACTTTCAAAAGGCGGAGAAAGAGGCGCTACG
TATGCTGTTTGAAGAGAAAGGGATCCCTCTAACTAGCGAGATTGAAGCGCAATATAAAAAAATTAATAAAAGTCTTTGGA
CTGCTTTTGAAGAAGGTGAAATAAATCGTGATGAAGTTGTAAATACACGATTTTCAATTTTGTTTAAAGAATACGGGGAA
GAAGTAGATGGGATATTATTCGAAAATAATTATCGCAGTTACTTAGAAGAAGGAAATCACCTCATGGAAGGTGCTTTACA
ATTTATAAATCAAATTCAAAGTGAGTACGATTTATATATAGTGACAAACGGTATTTCTAAGACGCAAGATAAACGGTTGC
GTAATGCAGGGTTACATTCAATGTTTAAAGATATTTTCGTTTCTGAAGATACAGGTTATCAAAAGCCAATGAAAGAGTAT
TTTGATTATGTTTTTGAAAGAATTCCTAATTTTGCTCCTGAAGAAGGGCTCATTATTGGGGATTCGTTAAGCGCTGATAT
GAAAGGTGGATATGTAGCGGGAATTGATACTTGTTGGTTTAATCCAGAAAAGAAATCAAATCATAGCGAGATTGTGCCAA
CATATGAAGTGCAGAATTTTGAGGAGTTATATGCAATATTGAAGCAGCGTGTGTAA

Upstream 100 bases:

>100_bases
ACCTCATACTTAGTATGAGATATCTCCTATTATTTTTACAAGAAAGAATGATACGATTTACGTAAATTTGTTTTTGTAGA
AAAGAGAGTGTGAGGGGTTT

Downstream 100 bases:

>100_bases
TAAAAATAGGCAGTAGAACTTTTGTCCCTACTGCCTATTTTTTTAATTTGTAGTTTCGTTATGTTTTGGAAGTGGAAATG
CATTTCCGGTAGCAGCTGCC

Product: HAD superfamily hydrolase

Products: (R)-2-hydroxyacid; halide

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKKYKILLFDVDDTLLDFQKAEKEALRMLFEEKGIPLTSEIEAQYKKINKSLWTAFEEGEINRDEVVNTRFSILFKEYGE
EVDGILFENNYRSYLEEGNHLMEGALQFINQIQSEYDLYIVTNGISKTQDKRLRNAGLHSMFKDIFVSEDTGYQKPMKEY
FDYVFERIPNFAPEEGLIIGDSLSADMKGGYVAGIDTCWFNPEKKSNHSEIVPTYEVQNFEELYAILKQRV

Sequences:

>Translated_231_residues
MKKYKILLFDVDDTLLDFQKAEKEALRMLFEEKGIPLTSEIEAQYKKINKSLWTAFEEGEINRDEVVNTRFSILFKEYGE
EVDGILFENNYRSYLEEGNHLMEGALQFINQIQSEYDLYIVTNGISKTQDKRLRNAGLHSMFKDIFVSEDTGYQKPMKEY
FDYVFERIPNFAPEEGLIIGDSLSADMKGGYVAGIDTCWFNPEKKSNHSEIVPTYEVQNFEELYAILKQRV
>Mature_231_residues
MKKYKILLFDVDDTLLDFQKAEKEALRMLFEEKGIPLTSEIEAQYKKINKSLWTAFEEGEINRDEVVNTRFSILFKEYGE
EVDGILFENNYRSYLEEGNHLMEGALQFINQIQSEYDLYIVTNGISKTQDKRLRNAGLHSMFKDIFVSEDTGYQKPMKEY
FDYVFERIPNFAPEEGLIIGDSLSADMKGGYVAGIDTCWFNPEKKSNHSEIVPTYEVQNFEELYAILKQRV

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Escherichia coli, GI1790833, Length=228, Percent_Identity=30.7017543859649, Blast_Score=117, Evalue=7e-28,
Organism=Drosophila melanogaster, GI28571108, Length=216, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.8.1.2

Molecular weight: Translated: 27007; Mature: 27007

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYKILLFDVDDTLLDFQKAEKEALRMLFEEKGIPLTSEIEAQYKKINKSLWTAFEEGE
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
INRDEVVNTRFSILFKEYGEEVDGILFENNYRSYLEEGNHLMEGALQFINQIQSEYDLYI
CCHHHHHHHHHHHHHHHHCHHHCCEEEECCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEE
VTNGISKTQDKRLRNAGLHSMFKDIFVSEDTGYQKPMKEYFDYVFERIPNFAPEEGLIIG
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
DSLSADMKGGYVAGIDTCWFNPEKKSNHSEIVPTYEVQNFEELYAILKQRV
CCCCCCCCCCEEEEEHHEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKYKILLFDVDDTLLDFQKAEKEALRMLFEEKGIPLTSEIEAQYKKINKSLWTAFEEGE
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
INRDEVVNTRFSILFKEYGEEVDGILFENNYRSYLEEGNHLMEGALQFINQIQSEYDLYI
CCHHHHHHHHHHHHHHHHCHHHCCEEEECCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEE
VTNGISKTQDKRLRNAGLHSMFKDIFVSEDTGYQKPMKEYFDYVFERIPNFAPEEGLIIG
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
DSLSADMKGGYVAGIDTCWFNPEKKSNHSEIVPTYEVQNFEELYAILKQRV
CCCCCCCCCCEEEEEHHEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-haloacid; H2O

Specific reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]