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The map label for this gene is murA [H]

Identifier: 118480368

GI number: 118480368

Start: 5090429

End: 5091718

Strand: Reverse

Name: murA [H]

Synonym: BALH_4832

Alternate gene names: 118480368

Gene position: 5091718-5090429 (Counterclockwise)

Preceding gene: 118480369

Following gene: 118480367

Centisome position: 96.85

GC content: 41.32

Gene sequence:

>1290_bases
ATGGAAAAATTGCTAATTGAAGGCGGAAGAGCTTTAAATGGAACAATTCGCGTGAGTGGTGCAAAGAATAGCGCCGTTGC
ATTAATTCCAGCGACAATTTTAGCAGATACTCCAGTAACTATTGGTGGTGTCCCTAATATTTCGGACGTGAAAATGTTAG
GAGACTTACTAGAGGAAATTGGAGGAAGAGTAACGTATGGACAGGAGGAAGAGATGGTAGTCGATCCTTCTAACATGGTT
GCAATGCCTTTACCAAACGGAAAAGTGAAAAAATTACGTGCTTCTTATTATTTAATGGGTGCGATGCTTGGCCGTTTTAA
AAAAGCTGTTATTGGGCTTCCAGGTGGATGTCACTTAGGACCGAGGCCGATTGATCAGCATATTAAAGGGTTTGAAGCGT
TAGGTGCACATGTTACGAATGAACAAGGTGCTATCTATTTAAGAGCAGATGAACTACGCGGGGCTCGTATTTATTTAGAT
GTTGTTAGCGTAGGAGCTACGATTAATATTATGCTAGCAGCCGTACGAGCGAAAGGTAGAACTGTTATTGAAAACGCAGC
GAAAGAACCAGAGATTATTGATGTAGCTACACTGTTAACTAGCATGGGAGCACGTATTAAAGGTGCTGGTACAGATGTAA
TCCGAATTGATGGTGTGGATTCATTGCACGGTTGTCATCATACGATCATTCCAGATCGTATTGAAGCGGGTACGTATATG
ATTTTAGGTGCTGCATCAGGAGGAGAAGTAACAGTTGATAATGTTATTCCTCAGCACTTAGAGTCAGTTACGGCGAAGCT
CCGAGAAGCTGGTGTCCAGGTTGAAACGAATGATGACCAGATTACAGTGAACGGTGATAGAAGATTAAAAGTAGTTGATA
TAAAAACGCTTGTATATCCAGGTTTCCCAACAGACTTACAACAGCCGTTTACAACACTTTTAACAAAGGCGCATGGAACG
GGTGTTGTAACGGATACGATTTATGGTGCACGTTTTAAACATATTGATGAATTACGTCGTATGAATGCACAAATTAAAGT
AGAAGGTCGGTCAGCTATCGTAACTGGTCCTGTTTTATTGCAAGGTGCAAAAGTGAAAGCGAGTGATTTGCGAGCTGGAG
CAGCCCTTGTTATTGCAGGATTAATGTCGGATGGAATTACAGAAGTAACCGGACTTGAGCATATTGATCGTGGCTATGAA
AATATAGTAGACAAGCTTAAAGGGCTCGGTGCAAACATTTGGCGAGAACAAATGACAAAGCAAGAAATTGAAGAAATGAA
GAACGCATAA

Upstream 100 bases:

>100_bases
ATTTATTGAGTTTTGGGATGGAAAAGTAATTGAGATTCTTAAGGGGGAGCTTTCTATAAAAATATAGAAAGTAAATACAT
TCACAAGAAGGGAGCTCAAT

Downstream 100 bases:

>100_bases
GTGATACTTCCGCAAGGGGGAAGCGAAGCATCACTACTTGCGGAAGTACACTTTATAGAAAAAACACGGTTCACAAAATA
CGGCAGAAATATAAAGACTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLD
VVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGT
GVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMSDGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTKQEIEEMKNA

Sequences:

>Translated_429_residues
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLD
VVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGT
GVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMSDGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTKQEIEEMKNA
>Mature_429_residues
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLD
VVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGT
GVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMSDGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTKQEIEEMKNA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=44.1247002398081, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45883; Mature: 45883

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEI
CCCEEECCCCEECCEEEEECCCCCEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
GGRVTYGQEEEMVVDPSNMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLG
CCEEECCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
PRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLDVVSVGATINIMLAAVRAKGR
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEECCCCEEEEHEEEHHHCCC
TVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCCHHCCCCCCCCCCCCCCCCEE
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYP
EEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEEEEEEC
GFPTDLQQPFTTLLTKAHGTGVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLL
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHEE
QGAKVKASDLRAGAALVIAGLMSDGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTK
ECCCEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QEIEEMKNA
HHHHHHHCC
>Mature Secondary Structure
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEI
CCCEEECCCCEECCEEEEECCCCCEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
GGRVTYGQEEEMVVDPSNMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLG
CCEEECCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
PRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLDVVSVGATINIMLAAVRAKGR
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEECCCCEEEEHEEEHHHCCC
TVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCCHHCCCCCCCCCCCCCCCCEE
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYP
EEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEEEEEEC
GFPTDLQQPFTTLLTKAHGTGVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLL
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHEE
QGAKVKASDLRAGAALVIAGLMSDGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTK
ECCCEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QEIEEMKNA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]