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The map label for this gene is tdk

Identifier: 118480365

GI number: 118480365

Start: 5086454

End: 5087041

Strand: Reverse

Name: tdk

Synonym: BALH_4829

Alternate gene names: 118480365

Gene position: 5087041-5086454 (Counterclockwise)

Preceding gene: 118480366

Following gene: 118480364

Centisome position: 96.77

GC content: 39.63

Gene sequence:

>588_bases
ATGTACTTAATAAATCAGAACGGTTGGATTGAAGTGATTTGCGGTAGTATGTTTTCTGGTAAATCAGAAGAGCTTATCCG
CCGTGTGCGTCGTACGCAATTTGCGAAACAACATGCAATTGTATTTAAACCATGTATTGATAATCGCTATAGTGAAGAAG
ACGTTGTATCACATAACGGATTAAAGGTAAAAGCAGTTCCTGTTTCAGCTTCAAAAGATATATTTGAACATATCACTGAA
GAAATGGATGTAATTGCAATTGATGAAGTGCAATTCTTTGATGGGGACATTGTGGAAGTGGTGCAAGTATTGGCAAATCG
TGGCTATCGTGTCATTGTAGCTGGTTTAGACCAAGATTTCCGTGGTCTACCATTTGGACAAGTTCCTCAGCTGATGGCGA
TTGCTGAACATGTAACAAAACTACAAGCTGTATGTTCTGCATGTGGATCTCCGGCAAGTCGTACACAACGATTAATTGAT
GGAGAACCAGCGGCATTTGATGATCCAATTATTTTAGTTGGGGCTTCAGAATCGTATGAACCACGCTGTCGTCATTGTCA
TGCAGTTCCTACAAACAAAGATAAGTAA

Upstream 100 bases:

>100_bases
TAAAACAGGCAAGTGTATCTATTCGCTTGTCTGTTTTTTTTGCGAAAATATTATACCTTTACCCTACTTTTAACGAAAAA
GTAGATGAAAGGAGAGCTTC

Downstream 100 bases:

>100_bases
AACTCGCTGTGCAAGGCGGGTTTTTTTCAGAATAGAGAGTGTGAGTGGTACGAGCCACCACCACTTTTAAATATAATTTG
CGTTTTTTTGAGTAAGTACC

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFEHITE
EMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLID
GEPAAFDDPIILVGASESYEPRCRHCHAVPTNKDK

Sequences:

>Translated_195_residues
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFEHITE
EMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLID
GEPAAFDDPIILVGASESYEPRCRHCHAVPTNKDK
>Mature_195_residues
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFEHITE
EMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLID
GEPAAFDDPIILVGASESYEPRCRHCHAVPTNKDK

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Homo sapiens, GI164698438, Length=195, Percent_Identity=40, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17543396, Length=186, Percent_Identity=34.9462365591398, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_BACAH (A0RLB6)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_897516.1
- ProteinModelPortal:   A0RLB6
- SMR:   A0RLB6
- STRING:   A0RLB6
- EnsemblBacteria:   EBBACT00000069232
- GeneID:   4543670
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_4829
- eggNOG:   COG1435
- GeneTree:   EBGT00050000002762
- HOGENOM:   HBG522108
- OMA:   VITGPMY
- ProtClustDB:   PRK04296
- BioCyc:   BTHU412694:BALH_4829-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 21716; Mature: 21716

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 89-89

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNG
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHCCCC
LKVKAVPVSASKDIFEHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDF
EEEEEEECCCCHHHHHHHHHHCCEEEECCEEECCCCHHHHHHHHHCCCCEEEEEECCCCC
RGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAAFDDPIILVGASESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRHCHAVPTNKDK
CHHHCCCCCCCCCCC
>Mature Secondary Structure
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNG
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHCCCC
LKVKAVPVSASKDIFEHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDF
EEEEEEECCCCHHHHHHHHHHCCEEEECCEEECCCCHHHHHHHHHCCCCEEEEEECCCCC
RGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAAFDDPIILVGASESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRHCHAVPTNKDK
CHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA