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The map label for this gene is ugd [H]

Identifier: 118480312

GI number: 118480312

Start: 5029545

End: 5030882

Strand: Reverse

Name: ugd [H]

Synonym: BALH_4773

Alternate gene names: 118480312

Gene position: 5030882-5029545 (Counterclockwise)

Preceding gene: 118480313

Following gene: 118480311

Centisome position: 95.7

GC content: 32.51

Gene sequence:

>1338_bases
ATGAATATTGCAGTTGTAGGTACAGGTTACGTAGGTTTAGTAACAGGTGTTTGTCTATCGGAGATTAATCATCAAGTTAT
ATGTATAGATACAGACGAAGAGAAAATAAAAAAAATGCAAGCTGGTATTTCACCAATATATGAACCAGGTTTAGATGAGT
TAATGCAAAAAAATATAAAAAAAGGTACTTTGCATTTTACAAATAATCATCAAAGAGGCTTTGCGGATGCTGAAGTTATA
TTTATTGCTGTAGGTACTCCACAAATGCCAGATGGTTCTGCTAATTTAGCATTTATTGAGGCTGTTGCCAAATCTATTGC
TAAATATGTTAGTCACGATATTATTGTAGTTACAAAAAGTACAGTTCCTGTTGGAACAAATGATTTTGTGAAGAAAATAA
TTTTAGAGAATTTGCAGCATAATGTAACTGTTAAAGTAGCATCCAATCCTGAGTTTTTACGTGAGGGATCAGCTATACAA
GATACATTCCAGGGAGATCGTATTGTTATTGGGACAGAAGATCAAGAAACTGCAAATATCTTAGAGGATATGTATAAAGA
ATTTAATTTACCAGTATTTAAAACAGATATTTACAGTTCGGAAATGATTAAATATGCATCTAATGCTTTCTTGGCTACAA
AGATTAGTTTTATTAACGAAATCTCCAATATTTGCGAGAAGTTAGGTGCAAATGTTGAAGATGTTGCAAGTGGAATGGGA
TTTGATCACCGAATTGGGCGTGCTTTTTTAAATGCAGGTATAGGATATGGAGGATCATGTTTTCCAAAAGATACTCATGC
CTTAGTACAAATAGCTGGTGGAGTAGAACACGACTTCACGTTGCTGAAATCTGTTATAGATGTAAATAATAATCAGCAGA
GCTTAATGGTAGAAAAAATTAAATATAGATTAGGAAATTTAAAAGGTCTGAAGATAGCTATGCTAGGTTTAGCGTTTAAG
CCAAATACCGATGATATGCGTGAAGCAGCTTCTATTGTGATTTCCAATCATTTGGTAGAAGAAGGGGCTAATATCTATGC
ATACGATCCAATTGCTATAGAAAAAGCGAAAGCTATCTTACCAAGTAACATAGTATATACAACTTCTCTTGATGAGTGCT
TAGAAGCAGCTGATGTAACTGTTATTGTTACAGAATGGGATGAGTTTAAAGCTATGGATTTAAACAAGTTTAAAGGATTA
GTTAAAACACCATTGTTATTTGATGGAAGAAATTGCTTTGATTTAGATGAAATGGACAAAAGAGGTATTGAATATCATTC
GGTAGGAAGACCTATAATTCGCAATATTAATAATAATAAAGAAAAAAGTTTAGTTTAA

Upstream 100 bases:

>100_bases
CACAACCCCTTTCTTTATCTTTTTAGGATTTCTTGTAGGAAGATACAGTATTCTAAGGAGAAAGTTATATCAATATAAAT
AAAATGCAGGAGGAGTAACT

Downstream 100 bases:

>100_bases
AATAATACTTATAGTGTAAAGCTTAGGGACGAGGTATATAAAAATTATTCCTTATCTCTAAGCTTTAAATTTTATTAAAG
GTGAGGATTTAATGAGAAAA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNIAVVGTGYVGLVTGVCLSEINHQVICIDTDEEKIKKMQAGISPIYEPGLDELMQKNIKKGTLHFTNNHQRGFADAEVI
FIAVGTPQMPDGSANLAFIEAVAKSIAKYVSHDIIVVTKSTVPVGTNDFVKKIILENLQHNVTVKVASNPEFLREGSAIQ
DTFQGDRIVIGTEDQETANILEDMYKEFNLPVFKTDIYSSEMIKYASNAFLATKISFINEISNICEKLGANVEDVASGMG
FDHRIGRAFLNAGIGYGGSCFPKDTHALVQIAGGVEHDFTLLKSVIDVNNNQQSLMVEKIKYRLGNLKGLKIAMLGLAFK
PNTDDMREAASIVISNHLVEEGANIYAYDPIAIEKAKAILPSNIVYTTSLDECLEAADVTVIVTEWDEFKAMDLNKFKGL
VKTPLLFDGRNCFDLDEMDKRGIEYHSVGRPIIRNINNNKEKSLV

Sequences:

>Translated_445_residues
MNIAVVGTGYVGLVTGVCLSEINHQVICIDTDEEKIKKMQAGISPIYEPGLDELMQKNIKKGTLHFTNNHQRGFADAEVI
FIAVGTPQMPDGSANLAFIEAVAKSIAKYVSHDIIVVTKSTVPVGTNDFVKKIILENLQHNVTVKVASNPEFLREGSAIQ
DTFQGDRIVIGTEDQETANILEDMYKEFNLPVFKTDIYSSEMIKYASNAFLATKISFINEISNICEKLGANVEDVASGMG
FDHRIGRAFLNAGIGYGGSCFPKDTHALVQIAGGVEHDFTLLKSVIDVNNNQQSLMVEKIKYRLGNLKGLKIAMLGLAFK
PNTDDMREAASIVISNHLVEEGANIYAYDPIAIEKAKAILPSNIVYTTSLDECLEAADVTVIVTEWDEFKAMDLNKFKGL
VKTPLLFDGRNCFDLDEMDKRGIEYHSVGRPIIRNINNNKEKSLV
>Mature_445_residues
MNIAVVGTGYVGLVTGVCLSEINHQVICIDTDEEKIKKMQAGISPIYEPGLDELMQKNIKKGTLHFTNNHQRGFADAEVI
FIAVGTPQMPDGSANLAFIEAVAKSIAKYVSHDIIVVTKSTVPVGTNDFVKKIILENLQHNVTVKVASNPEFLREGSAIQ
DTFQGDRIVIGTEDQETANILEDMYKEFNLPVFKTDIYSSEMIKYASNAFLATKISFINEISNICEKLGANVEDVASGMG
FDHRIGRAFLNAGIGYGGSCFPKDTHALVQIAGGVEHDFTLLKSVIDVNNNQQSLMVEKIKYRLGNLKGLKIAMLGLAFK
PNTDDMREAASIVISNHLVEEGANIYAYDPIAIEKAKAILPSNIVYTTSLDECLEAADVTVIVTEWDEFKAMDLNKFKGL
VKTPLLFDGRNCFDLDEMDKRGIEYHSVGRPIIRNINNNKEKSLV

Specific function: Catalyzes the conversion of UDP-glucose into UDP- glucuronate, one of the precursors of teichuronic acid [H]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=465, Percent_Identity=36.7741935483871, Blast_Score=262, Evalue=6e-70,
Organism=Homo sapiens, GI296040438, Length=365, Percent_Identity=38.0821917808219, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI296040443, Length=316, Percent_Identity=38.6075949367089, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI1788340, Length=363, Percent_Identity=30.3030303030303, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI48994968, Length=413, Percent_Identity=26.634382566586, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17560350, Length=466, Percent_Identity=34.7639484978541, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI17136908, Length=467, Percent_Identity=34.2612419700214, Blast_Score=256, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49034; Mature: 49034

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAVVGTGYVGLVTGVCLSEINHQVICIDTDEEKIKKMQAGISPIYEPGLDELMQKNIK
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHCCCC
KGTLHFTNNHQRGFADAEVIFIAVGTPQMPDGSANLAFIEAVAKSIAKYVSHDIIVVTKS
CCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEC
TVPVGTNDFVKKIILENLQHNVTVKVASNPEFLREGSAIQDTFQGDRIVIGTEDQETANI
CCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCHHHHHCCCCEEEEECCCHHHHHH
LEDMYKEFNLPVFKTDIYSSEMIKYASNAFLATKISFINEISNICEKLGANVEDVASGMG
HHHHHHHHCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
FDHRIGRAFLNAGIGYGGSCFPKDTHALVQIAGGVEHDFTLLKSVIDVNNNQQSLMVEKI
CHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
KYRLGNLKGLKIAMLGLAFKPNTDDMREAASIVISNHLVEEGANIYAYDPIAIEKAKAIL
HHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHC
PSNIVYTTSLDECLEAADVTVIVTEWDEFKAMDLNKFKGLVKTPLLFDGRNCFDLDEMDK
CCCEEEECCHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHH
RGIEYHSVGRPIIRNINNNKEKSLV
CCCCHHHCCCHHHHCCCCCCHHCCC
>Mature Secondary Structure
MNIAVVGTGYVGLVTGVCLSEINHQVICIDTDEEKIKKMQAGISPIYEPGLDELMQKNIK
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHCCCC
KGTLHFTNNHQRGFADAEVIFIAVGTPQMPDGSANLAFIEAVAKSIAKYVSHDIIVVTKS
CCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEC
TVPVGTNDFVKKIILENLQHNVTVKVASNPEFLREGSAIQDTFQGDRIVIGTEDQETANI
CCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCHHHHHCCCCEEEEECCCHHHHHH
LEDMYKEFNLPVFKTDIYSSEMIKYASNAFLATKISFINEISNICEKLGANVEDVASGMG
HHHHHHHHCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
FDHRIGRAFLNAGIGYGGSCFPKDTHALVQIAGGVEHDFTLLKSVIDVNNNQQSLMVEKI
CHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
KYRLGNLKGLKIAMLGLAFKPNTDDMREAASIVISNHLVEEGANIYAYDPIAIEKAKAIL
HHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHC
PSNIVYTTSLDECLEAADVTVIVTEWDEFKAMDLNKFKGLVKTPLLFDGRNCFDLDEMDK
CCCEEEECCHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHH
RGIEYHSVGRPIIRNINNNKEKSLV
CCCCHHHCCCHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]