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The map label for this gene is fadB [H]

Identifier: 118480098

GI number: 118480098

Start: 4780345

End: 4782726

Strand: Reverse

Name: fadB [H]

Synonym: BALH_4547

Alternate gene names: 118480098

Gene position: 4782726-4780345 (Counterclockwise)

Preceding gene: 118480100

Following gene: 118480097

Centisome position: 90.98

GC content: 39.29

Gene sequence:

>2382_bases
ATGTTCCAAATTAAAAAGGCTGCTGTTCTAGGGTCAGGCGTAATGGGTTCAGGAATTGCGGCACACTTAGCTAATATTGG
TATTCCGACATTATTGCTTGATATTGTACCACCTGCGCTTACGAAAGAAGAAGAGGCGAAGGGACTTACATTAGAACATA
AAAGTGTGAGAAATCGTTTTAGTAATACGGCTGTGCAAAAACTATTAAAGCAAAAACCAGCTCCTCTGACAGTGAAAGGA
AATTTAGCACTGATTGAAGCAGGTAACTTAGAAGATGATCTTGAGCGTCTAGCTGATGTAGATTGGATTATTGAAGTAGT
AGTTGAAAACTTAGATATTAAAAAGAAACTATTTGAAAAAGTAGATGCTGTTCGTAAACCGGGTTCTATCGTAAGCTCGA
ATACGTCAGGCATTTCAGTTGAAAAAATGGCAGAAGGTCGTTCAGACGACTTCCAGAAACACTTCTTAGGCACACACTTT
TTTAACCCACCACGATATTTAAAACTTCTAGAGGTAATACCGACGAAAAAAACTGATCCACAAGTATTAAGCTTCATGAA
ACTATTTGGCGAAGACGTTCTTGGAAAAGGCGTTGTTATCGCAAAAGACACACCAAACTTTATTGGAAACCGCATCGGTA
CGTACGGTTTATTAGTAACTCTTCAAGAGATGGTAAAACGCGGCTATAGCATTGGAGAAGTTGATTCAGTAACAGGCCCA
CTTATTGGTCGTCCGAAGAGCGCAACGTTCCGTACTTTAGATGTTGTCGGTTTAGATACATTCGTACACGTTGCAAATAA
CGTATATGAAAACGTACAAGAAAAAGAGCGCGATGTATTTAAAGTACCAGCTTTCATGCATGACATGCTTGATAAAAAAT
GGCTGGGAAGCAAAACAGGTCAAGGCTTCTTCTTAAAACAAGGAAAAGAAATTTTAGAATTAAATCCAGAAACGATGGAG
TACGAAGCTCGTAAAAAATTAAAAGCTGCATCGATTGAGTTAAGTAAACAAGAAAAAGGTTTATCGAATAAATTGAAAGC
GCTTGTATATGCGAAAGACCGCGCAGGAGAGTTGTTATGGAATATCATCACACCGACTCTTTTATATTCTGCAAAACTTC
ATAAAGAGATTGCTGACGATATCGTTGCAATTGACCAAGCGATGAAGTGGGGCTTCGGCTGGGAGCAAGGCCCATTTGAA
GTTTGGGATGCAATTGGCGTTGAAAAGTCCGTTCAAAAGATGGAAGAAAGCGGCGCAGTTATTCCGGCTTGGGTGAAAGA
AATGTTAGAGAAAGGTTTCACTACTTTCTACAAACATGATAACGGAGATAGCTATTATTACGATAATGGCGAATATAAGC
TAATTGAGCGTAATAAAAAGGCAATTTCTCTTAAACAATTAAAAGCGAAAAATGGTGTATTAAAGAAAAATAGCGGAGCG
AGCTTAATCGATTTAGGCGACGGTATCCTTTGCTTAGAATTCCATTCGAAGAGCAATGCAATCGGTATGGATATTACGCA
AATGATTAACTACGCTGTTGATGAAGTAGAAAAGAATTATAAAGGTCTTGTTATCGGTAACCAATCGAAGAACTTCTGCG
TTGGTGCGAATCTAGCAATGATCTTAATGGAAGCACAAGACGACAACTACTTTGAAATTGAGTGGGTTGTGAAAAACTTC
CAAGATGCAATGATGAAAATTAAATACTCTTCTAAGCCAGTTGTAGCAGCGCCATATGGTATGACGCTTGGCGGAGGTAC
AGAAGTTTGCTTACCAGCAGCGAGCATTCAAGCTTCTAGTGAAACGTATATGGGCTTAGTAGAAGTTGGTGTTGGCTTAA
TCCCTGGCGGAGGCGGTAATAAAGAGCTATACATTAAACACTTAAATAAAATGGCAAACGGCGTAGAGTTTGACTTGCAA
AAAGTTGCAAATAAAGTGTTCGAAACAGTCGCAATGGCGAAAGTTTCAACTTCAGGACAAGAAGCGGTTTCTCATAACTT
CTTAGGTGATAAAGACGGTATTAGTGTGAATGGTGATCACTTACTATACGATGCGAAACAGAAAGCACTTGCTCTATATG
AAGCTGGTTATAAAGCGCCGATCCGTAAGAAGATACCGGTTGTTGGTGAAACAGGATATGCAACTCTTGCACTTGGTGCA
GAAGCAATGCATTTATCTGGTTATATTTCAGAGTACGACCTTCATATTGCGAAGAAACTTGCATATGTCATCGCAGGCGG
AAAAGTGCCGTACGGAACAGAAGTTGATGAGCAGTATTTATTAGATGTAGAACGTGAAGCATTTATTAGCTTAGTCAGTG
AGATGAAATCACAGGCAAGAATGCAGCACATGCTTGTAAAAGGAAAGCCATTACGTAACTAA

Upstream 100 bases:

>100_bases
TAAACAGTATCATATATTTATTAGTAGAGGCTCACTCATTGATTGCGACTTATGTCGAAAAATTGAATGAGCATTCATTC
AAGAATAGGGGGAGAATTGG

Downstream 100 bases:

>100_bases
TAACGAGGGGAGATATCGTTCATGAGAGAAGCTGTCATTGTTGCGGGAGCAAGAACACCAATTGGAAAAGCAAAGAGGGG
TTCATTAAAAACAGTTCGTC

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN

Sequences:

>Translated_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN
>Mature_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=301, Percent_Identity=29.2358803986711, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI296179427, Length=322, Percent_Identity=28.2608695652174, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI20127408, Length=417, Percent_Identity=25.8992805755396, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI261878539, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI68989263, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI115430219, Length=229, Percent_Identity=27.5109170305677, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787661, Length=304, Percent_Identity=26.9736842105263, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790281, Length=318, Percent_Identity=24.8427672955975, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1788682, Length=283, Percent_Identity=27.208480565371, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17553560, Length=308, Percent_Identity=32.1428571428571, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17549919, Length=303, Percent_Identity=30.03300330033, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71985923, Length=416, Percent_Identity=26.6826923076923, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508951, Length=418, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=418, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17563036, Length=301, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=425, Percent_Identity=25.4117647058824, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=303, Percent_Identity=27.7227722772277, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985930, Length=327, Percent_Identity=24.1590214067278, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45549573, Length=275, Percent_Identity=28, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24583077, Length=417, Percent_Identity=25.6594724220624, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24583079, Length=417, Percent_Identity=25.6594724220624, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19921000, Length=417, Percent_Identity=25.6594724220624, Blast_Score=87, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 87459; Mature: 87459

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCEEEHHHHHHHH
SNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEK
HHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKKTDP
HHHHCCCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCH
QVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLW
CCEEHHCCCHHHHCCCHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHEEEEECCCHHHHHH
NIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEESGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCC
IPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
CHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKNFQDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASS
EEEECCCCCEEEEHHHHHHHHHHHHEEEECCCCEEECCCCEEECCCCCEEEECHHCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
HHHHHCCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCCCHHCCCEECCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC
>Mature Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCEEEHHHHHHHH
SNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEK
HHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKKTDP
HHHHCCCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCH
QVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLW
CCEEHHCCCHHHHCCCHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHEEEEECCCHHHHHH
NIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEESGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCC
IPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
CHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKNFQDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASS
EEEECCCCCEEEEHHHHHHHHHHHHEEEECCCCEEECCCCEEECCCCCEEEECHHCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
HHHHHCCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCCCHHCCCEECCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]