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The map label for this gene is metQ [H]

Identifier: 118480069

GI number: 118480069

Start: 4755944

End: 4756765

Strand: Reverse

Name: metQ [H]

Synonym: BALH_4517

Alternate gene names: 118480069

Gene position: 4756765-4755944 (Counterclockwise)

Preceding gene: 118480070

Following gene: 118480068

Centisome position: 90.48

GC content: 32.85

Gene sequence:

>822_bases
ATGTTTCAAATGAAAAAATTATTACTTACAGCACTTATTTCAACTTCAATTTTTGGGTTAGCTGCTTGTGGGGGGAAAGA
TAACGATGAAAAGAAACTAGTTGTTGGTGCTTCTAACGTACCGCACGCTGAAATTTTAGAAAAGGCAAAACCGTTACTTG
AGAAAAAAGGAATTGAATTAGAAGTGAAAAAATTCCAAGATTACGTGTTGCCAAATAAATCGTTAGCGGATAAGGATTTA
GACGCTAACTACTTCCAGCACATTCCGTATTTAGAAAAAGAAATTAAAGATAAAAAGTATGATTTTGAAGTAGCAGGAAA
AATTCATTTAGAGCCAATTGGTGTATATTCTCAAAAATATAAAAGCTTAAAAGAGCTTCCAGACGGAGCGACAATTATTA
TGAGTAATTCAGTTGCTGACCATGGACGTGGTTTAGCAATTTTACAAAAAGAAGGTATTTTAAAAATTAAAGATGGAGTA
GATCCAGTTAAAGCAACTCCGAAAGATATTGCGGATAATCCGAAAAACTTAAAATTCAAAACGGATATTGAGCCTGGTTT
ATTGCCACAAGTGTATAACAATAAAGAAGGCGACGCTGTTCTAATTAACTCAAACTATGCAATTGATGCGAAGTTAAATC
CAGAAAAAGATGCAATTGCAATTGAAAGCAATGATTCACCGTATGCAAACGTAGTAGCTGTTCGTAAAGGCGATAAAGAT
AAAAAAGAAATTAAAGCTCTTGTAGAAGTATTACATTCTAAAGAAATTGAAGACTTCATTAACAAAGAATATAAAGGGGC
AGTTGTTCCTGTAAAAGAATAA

Upstream 100 bases:

>100_bases
TCGTTGCGACAATTTGTGTATTACTAGTTGTATTTTTCATTCAGTGGATTGGCGATCGTGTAACGACTCGAATAGATAAA
CGATAATAAAAAACGGGAGG

Downstream 100 bases:

>100_bases
TTGCTGCGGAAGGGCTGGTGTATGCCGGCCCTTTTTATAACTACATAATTATACGGGAGAAGGGGACATCATATGAAAAA
GATTCTATTGTCAGTTGTTA

Product: ABC transporter substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MFQMKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDL
DANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGV
DPVKATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKD
KKEIKALVEVLHSKEIEDFINKEYKGAVVPVKE

Sequences:

>Translated_273_residues
MFQMKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDL
DANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGV
DPVKATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKD
KKEIKALVEVLHSKEIEDFINKEYKGAVVPVKE
>Mature_273_residues
MFQMKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDL
DANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGV
DPVKATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKD
KKEIKALVEVLHSKEIEDFINKEYKGAVVPVKE

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable) [H]

COG id: COG1464

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface antigen

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpA lipoprotein family [H]

Homologues:

Organism=Escherichia coli, GI1786396, Length=260, Percent_Identity=37.3076923076923, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1790093, Length=249, Percent_Identity=31.3253012048193, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004872 [H]

Pfam domain/function: PF03180 Lipoprotein_9 [H]

EC number: NA

Molecular weight: Translated: 30268; Mature: 30268

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQMKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIEL
CCHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEE
EVKKFQDYVLPNKSLADKDLDANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKY
EEEHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCEEEECEEEEEECCHHHHHH
KSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGVDPVKATPKDIADNPKNLKFK
HHHHHCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHCCCCCCCEEE
TDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKD
ECCCCCCCCHHHCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCEEEEEEECCCCH
KKEIKALVEVLHSKEIEDFINKEYKGAVVPVKE
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure
MFQMKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIEL
CCHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEE
EVKKFQDYVLPNKSLADKDLDANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKY
EEEHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCEEEECEEEEEECCHHHHHH
KSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGVDPVKATPKDIADNPKNLKFK
HHHHHCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHCCCCCCCEEE
TDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKD
ECCCCCCCCHHHCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCEEEEEEECCCCH
KKEIKALVEVLHSKEIEDFINKEYKGAVVPVKE
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]