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The map label for this gene is vpr [H]

Identifier: 118479520

GI number: 118479520

Start: 4151642

End: 4154395

Strand: Direct

Name: vpr [H]

Synonym: BALH_3942

Alternate gene names: 118479520

Gene position: 4151642-4154395 (Clockwise)

Preceding gene: 118479515

Following gene: 118479521

Centisome position: 78.97

GC content: 37.18

Gene sequence:

>2754_bases
ATGAAAAAAACTACATCTACACTTTTAAGTATGGCACTCGTCTTTTCTAGTTTTGGAGCTTTAAGCGCCCATGCTGAATC
ACTGCAAAAGGAGAAGCAATTTAGTCCACAACTAAAAACAACGATTGAACAATGGGGAGAAAGTAAAATTGCTCAACACG
TTGAAACAAAAACAACAAAAGAAATATCTGTAATTGTAGAATTGCAACATGCACCTCTTGCCGCGCAAAGTAACATTCAG
CATGCTCCAGATTTACAAAATAGTCATGCACAGTCTTATCATACCGAGCTAAAAAAAGCACAAGAAGAGACAACTAAGAA
AATAAAAGAAAAAGCACCTGGTGCAAAAATTAAAGAAGTTTATAATACGTTATTTTCTGGTTTCTCTATTTCAGTTCCAG
GAGATCAAATTACTGCTCTTGCTTCTTTACCTGAAGTAAAGACAGTCTATCCGAACTTAACATATAAATTGCATGAAACA
ACGAAAAGCGCTACTAGCGAAGAAGCACCTAATATTGGTGGACCGACAATTGGTGCTCCTGAAGCATGGAATTTAAAAGA
CCCATCTGGTAAATCTCTTGATGGAAAAGGTATGAAAGTAGCGATTATCGATTCTGGCGTAGACTATACACATCCTGACT
TAAAGGCAAATTATATTGGTGGATACGACACAGTGGATGAAGATGATGATCCAATGGATGGTAACGTACACGGTACTCAT
GTAGCTGGAATTATTGCTGGTAATGGAAAAATTAAAGGCGTTGCTCCGAATGCTTCTATTTTAGCTTATCGTGTCATGAA
TGACGGTGGTACTGGTACAACAGATGATATTATTCAAGGTATTGAACGAGCAATTCAAGATGGTGCTGATGTGTTAAATC
TATCCCTTGGACAAGATTTAAATGTACCTGATCAGCCTGTAACTTTAACGTTAGAACGTGCAGCAAAGCTTGGGGTTACT
GCAGTCGTTTCCAATGGAAATGATGGTCCAAAACCTTGGTCTGTTGATGCACCTGGAAATGCAAGTAGCGTGATATCAGT
TGGAGCATCTACAGTTTCTATTCCGTTTCCAACATTCCAAGTAGCTGGTTCCAGCAAAACATACCAAGGATTACCGTTAT
CAAAATCAGATTTCCCAATAGGAAATGATTCTCCACTTGTATATGTTGGCTATGGTAATCCAAGCGATTATGCAAAACAA
GATGTGAAAGGAAAATTTGCACTTGTTTTACAAGGTACTTCTAGCACGTTAGTAAAAGCTGAACAAGCGAAGCAAGCTGG
TGCAATTGGTGTACTATTCATTTCTACAGAAAAAGAAATGAATATTATGCCTGAATACTTTACACGTGAAAACCTAGCCC
TTCCAGTTATGCAACTATCCAATGTAAACGGTGAAGAGTTGAAAAATTTAATTACAAAGCGTAAGAAAAATATAAAGATC
GGACAACCGATTCCGACTGAATTAATTGGAAACTTTAGTTCCAGAGGTCCATCACAAGGAAGCTGGCTTATAAAACCAGA
TATCGTTGCACCTGGCGTACAAATTACTAGTACCGTACCACGAGGTGGCTATGAATCTCATAACGGAACAAGTATGGCTG
CTCCGCAAGTAGCTGGAGCGGTTGCCCTCCTGCGTCAAATGCACCCTGATTGGACGACGGAACAATTAAAAGCATCACTT
GCCAATACAGCAAAAACTTTAAAAGATGTTAATGAAAATACGTATCCTGTTATGACGCAAGGATCTGGCTTAATTAACAT
TCCAAAAGCTGTTCAAACAAGTGTATTAGTACAGCCTAACAATATCAGCTTCGGTCTTATAAAACCAAACAGTGGTAAAG
TAAAACTGACGCAAAATATTACGTTACAAAATCTTTCTAGTAAAAAGAAAAGCTTTTCAACTCGTATAGAATTACTAGAT
GCAAACACAAAAACAAAAATAAAAGCTTCTGTTCCTTCATCAATTAGCGTACAACCAAATAGTAATACGGAAAAACCATT
TACTATCACTGTCGATAGCTCACTACCACAAGGTGTGTATACTGGGAATGTATATGTAAAAGAGCAGGGAGCGAAAGAAG
AAATTCGAATTCCATTTACATTTAGTATCGATCCTAAAGATTATAAACGTATTGATGGTCTCGAAATTGTGAATTCTACT
TTTAGTCCAAACGGAGATAACATATTAGATGATAATCTCATCAACTACTATTTAGTTTCTCCTGTTGAAGATGTAACGTT
ACATGCTAACTTAGTTACAAAAGAACGTGTGACATACGAAGGAATCATTTATGAAGGTAAAAATGAAACAGCAGGTTATA
AACCTTTCAAATGGAATGGTACAAAAGTAGATGGATCACCACTCGCGGATGGTTTATATCAAATTGAAGCTGTTGCTTCT
AATTCTGGCGGAGAAACGAAACAAACGGCGGCTGTATTTATTGACCGAACTGCACCAAAATTGACGCATGAAGTTGATCA
AGAAAATCTCGTAATTAGAGGAAAAGTTGACGATATTCTACTAGATTGGATGACAGAATCTGGTTGGGTAGCACCTGGAA
TTCCAGTGAGACTACAGTATGAAATCAACGGAAATGGTGTATGGGAACATGCATTCCTGAACCCTTGGGAGAAAAACTAT
GACATTTATCTAGATCGTCCTCAATTACAAGAAGGTAAAAATACAATTCACATTGTAGCAACAGATGCAGCTGGAAATAC
ATCTAATTTAAATGTTGATTTAAATGTAAAATAA

Upstream 100 bases:

>100_bases
GTCGAAAATATAGTTTAGCCAACATTCGTTTTTATATTTCATAATAAAAATGTAAGATAACTTTTTGGAATATTGACACT
TTTTATTAGGGGGAGTTTCA

Downstream 100 bases:

>100_bases
AAAATTATTGTTGACAATTTTTTTAATATAGTTTTATAATACAAAACATAGTTTAGTTGAACGAATTATATATCGGCTTT
GAAGGAATACTAGTAGCGAC

Product: peptidase Vpr

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 917; Mature: 917

Protein sequence:

>917_residues
MKKTTSTLLSMALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTKEISVIVELQHAPLAAQSNIQ
HAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEVYNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHET
TKSATSEEAPNIGGPTIGAPEAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDLNVPDQPVTLTLERAAKLGVT
AVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQVAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQ
DVKGKFALVLQGTSSTLVKAEQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
GQPIPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGAVALLRQMHPDWTTEQLKASL
ANTAKTLKDVNENTYPVMTQGSGLINIPKAVQTSVLVQPNNISFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRIELLD
ANTKTKIKASVPSSISVQPNSNTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEEIRIPFTFSIDPKDYKRIDGLEIVNST
FSPNGDNILDDNLINYYLVSPVEDVTLHANLVTKERVTYEGIIYEGKNETAGYKPFKWNGTKVDGSPLADGLYQIEAVAS
NSGGETKQTAAVFIDRTAPKLTHEVDQENLVIRGKVDDILLDWMTESGWVAPGIPVRLQYEINGNGVWEHAFLNPWEKNY
DIYLDRPQLQEGKNTIHIVATDAAGNTSNLNVDLNVK

Sequences:

>Translated_917_residues
MKKTTSTLLSMALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTKEISVIVELQHAPLAAQSNIQ
HAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEVYNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHET
TKSATSEEAPNIGGPTIGAPEAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDLNVPDQPVTLTLERAAKLGVT
AVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQVAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQ
DVKGKFALVLQGTSSTLVKAEQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
GQPIPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGAVALLRQMHPDWTTEQLKASL
ANTAKTLKDVNENTYPVMTQGSGLINIPKAVQTSVLVQPNNISFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRIELLD
ANTKTKIKASVPSSISVQPNSNTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEEIRIPFTFSIDPKDYKRIDGLEIVNST
FSPNGDNILDDNLINYYLVSPVEDVTLHANLVTKERVTYEGIIYEGKNETAGYKPFKWNGTKVDGSPLADGLYQIEAVAS
NSGGETKQTAAVFIDRTAPKLTHEVDQENLVIRGKVDDILLDWMTESGWVAPGIPVRLQYEINGNGVWEHAFLNPWEKNY
DIYLDRPQLQEGKNTIHIVATDAAGNTSNLNVDLNVK
>Mature_917_residues
MKKTTSTLLSMALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTKEISVIVELQHAPLAAQSNIQ
HAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEVYNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHET
TKSATSEEAPNIGGPTIGAPEAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDLNVPDQPVTLTLERAAKLGVT
AVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQVAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQ
DVKGKFALVLQGTSSTLVKAEQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
GQPIPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGAVALLRQMHPDWTTEQLKASL
ANTAKTLKDVNENTYPVMTQGSGLINIPKAVQTSVLVQPNNISFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRIELLD
ANTKTKIKASVPSSISVQPNSNTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEEIRIPFTFSIDPKDYKRIDGLEIVNST
FSPNGDNILDDNLINYYLVSPVEDVTLHANLVTKERVTYEGIIYEGKNETAGYKPFKWNGTKVDGSPLADGLYQIEAVAS
NSGGETKQTAAVFIDRTAPKLTHEVDQENLVIRGKVDDILLDWMTESGWVAPGIPVRLQYEINGNGVWEHAFLNPWEKNY
DIYLDRPQLQEGKNTIHIVATDAAGNTSNLNVDLNVK

Specific function: Not required for growth or sporulation [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=155, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983555, Length=213, Percent_Identity=31.924882629108, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25141268, Length=213, Percent_Identity=31.924882629108, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320775, Length=254, Percent_Identity=31.1023622047244, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324576, Length=251, Percent_Identity=29.0836653386454, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550681, Length=211, Percent_Identity=30.8056872037915, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259
- InterPro:   IPR003137 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF02225 PA; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 98962; Mature: 98962

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER ; PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTTSTLLSMALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTK
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCC
EISVIVELQHAPLAAQSNIQHAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEV
EEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHETTKSATSEEAPNIGGPTIGAP
HHHHHCCCEEECCCCCEEHHHCCCCCEEECCCCEEEEECCHHCCCCCCCCCCCCCCCCCC
EAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEE
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDL
EEEEEECCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCC
NVPDQPVTLTLERAAKLGVTAVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQ
CCCCCCEEEEEEHHHHCCEEEEEECCCCCCCCEECCCCCCCCCEEEECCCEEEECCCCEE
VAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQDVKGKFALVLQGTSSTLVKA
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHH
EQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
HHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHHCCCCC
GQPIPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGA
CCCCCHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
VALLRQMHPDWTTEQLKASLANTAKTLKDVNENTYPVMTQGSGLINIPKAVQTSVLVQPN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCHHHCEEEEEECC
NISFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRIELLDANTKTKIKASVPSSISVQPN
CCEEEEECCCCCCEEEEECCEEHHHHHHHHHHCEEEEEEECCCCEEEEEECCCEEEECCC
SNTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEEIRIPFTFSIDPKDYKRIDGLEIVNST
CCCCCCEEEEECCCCCCCEEECEEEEECCCCCCEEEEEEEEEECCHHHHHCCCCCEECCC
FSPNGDNILDDNLINYYLVSPVEDVTLHANLVTKERVTYEGIIYEGKNETAGYKPFKWNG
CCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCEEEEEEEEECCCCCCCCCCEECCC
TKVDGSPLADGLYQIEAVASNSGGETKQTAAVFIDRTAPKLTHEVDQENLVIRGKVDDIL
CEECCCHHHCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCCCCEEEEECHHHHH
LDWMTESGWVAPGIPVRLQYEINGNGVWEHAFLNPWEKNYDIYLDRPQLQEGKNTIHIVA
HHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCEEECCCHHHCCCCEEEEEE
TDAAGNTSNLNVDLNVK
ECCCCCCCEEEEEEEEC
>Mature Secondary Structure
MKKTTSTLLSMALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTK
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCC
EISVIVELQHAPLAAQSNIQHAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEV
EEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHETTKSATSEEAPNIGGPTIGAP
HHHHHCCCEEECCCCCEEHHHCCCCCEEECCCCEEEEECCHHCCCCCCCCCCCCCCCCCC
EAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEE
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDL
EEEEEECCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCC
NVPDQPVTLTLERAAKLGVTAVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQ
CCCCCCEEEEEEHHHHCCEEEEEECCCCCCCCEECCCCCCCCCEEEECCCEEEECCCCEE
VAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQDVKGKFALVLQGTSSTLVKA
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHH
EQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
HHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHHCCCCC
GQPIPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGA
CCCCCHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
VALLRQMHPDWTTEQLKASLANTAKTLKDVNENTYPVMTQGSGLINIPKAVQTSVLVQPN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCHHHCEEEEEECC
NISFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRIELLDANTKTKIKASVPSSISVQPN
CCEEEEECCCCCCEEEEECCEEHHHHHHHHHHCEEEEEEECCCCEEEEEECCCEEEECCC
SNTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEEIRIPFTFSIDPKDYKRIDGLEIVNST
CCCCCCEEEEECCCCCCCEEECEEEEECCCCCCEEEEEEEEEECCHHHHHCCCCCEECCC
FSPNGDNILDDNLINYYLVSPVEDVTLHANLVTKERVTYEGIIYEGKNETAGYKPFKWNG
CCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCEEEEEEEEECCCCCCCCCCEECCC
TKVDGSPLADGLYQIEAVASNSGGETKQTAAVFIDRTAPKLTHEVDQENLVIRGKVDDIL
CEECCCHHHCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCCCCEEEEECHHHHH
LDWMTESGWVAPGIPVRLQYEINGNGVWEHAFLNPWEKNYDIYLDRPQLQEGKNTIHIVA
HHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCEEECCCHHHCCCCEEEEEE
TDAAGNTSNLNVDLNVK
ECCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1938892; 7934828; 9384377; 10658653 [H]