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The map label for this gene is pagR [H]

Identifier: 118479434

GI number: 118479434

Start: 4064862

End: 4065164

Strand: Direct

Name: pagR [H]

Synonym: BALH_3854

Alternate gene names: 118479434

Gene position: 4064862-4065164 (Clockwise)

Preceding gene: 118479433

Following gene: 118479449

Centisome position: 77.32

GC content: 32.67

Gene sequence:

>303_bases
GTGGAAAAAAACATGTTAGAAACCTTTCAAAAAGAAATAGAACTATATGAAAGCAATGCAGAATTATTGAAAGTACTTGC
TCATCCTGTTCGCTTATGTATTGTAAAAGGATTAATTGAACGTGGTCCAAGCAACGTTTCTACAATGTACACTGGCTTAA
ACATGCCACAATCTACAATTTCACAGCATTTAGCAAAATTAAAAAGTGCTAAAATCGTTTCAAGCGAAAGAAAAGGTTTG
GAAATTTATTACAAAGTAGAAAACGAGACAATTATTCAACTCGTTCGCGTATTATTGGGTTAG

Upstream 100 bases:

>100_bases
TCTTACAATTTCTTTACTTTAGGAATGTTTTTCTGCAACAACTGTTTTCTTTTCTTTAATTTTTTGGTATGTATAGTATG
GTATAACAGCTCACACGGAG

Downstream 100 bases:

>100_bases
GGACTCATAAACAGAGAAAAAGGACGTATTTTATATTTTTCATCTCATATCTTTAATATAAATATATATCATGAGAGGAA
ATATATGATGCTACATAAGT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 100; Mature: 100

Protein sequence:

>100_residues
MEKNMLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGL
EIYYKVENETIIQLVRVLLG

Sequences:

>Translated_100_residues
MEKNMLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGL
EIYYKVENETIIQLVRVLLG
>Mature_100_residues
MEKNMLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTISQHLAKLKSAKIVSSERKGL
EIYYKVENETIIQLVRVLLG

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11348; Mature: 11348

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNMLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTI
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHH
SQHLAKLKSAKIVSSERKGLEIYYKVENETIIQLVRVLLG
HHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHC
>Mature Secondary Structure
MEKNMLETFQKEIELYESNAELLKVLAHPVRLCIVKGLIERGPSNVSTMYTGLNMPQSTI
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHH
SQHLAKLKSAKIVSSERKGLEIYYKVENETIIQLVRVLLG
HHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]