Click here to switch to the map view.

The map label for this gene is buk [H]

Identifier: 118479357

GI number: 118479357

Start: 3986521

End: 3987651

Strand: Reverse

Name: buk [H]

Synonym: BALH_3774

Alternate gene names: 118479357

Gene position: 3987651-3986521 (Counterclockwise)

Preceding gene: 118479358

Following gene: 118479356

Centisome position: 75.85

GC content: 37.75

Gene sequence:

>1131_bases
TTGAATTTATTAGTGGAGGTAGCAACAGTGTCTGTAAATCGAATTCTTGTTATTAATCCGGGTAGTACATCCACAAAAAT
TGGTGTTTTTGATAATGAAAGACCCGTTTTAGAAGAAACTATTCGTCATGATGAAGAACAGATTGGAAAATATAAGCGAA
TTATCGACCAATATGAGTTTCGTAAAGAAACGATCTTAGAAGTTCTACATTCTCACGGTATTAACATTTCAAAATTAAAC
GCAGTTTGTGGACGCGGGGGATTACTTCGTCCAATCGAAGGCGGAACATACACAGTAAACGATGCGATGTTAGAAGATTT
AAAAAATGGTTTTAGTGGTCATCACGCTTCAAACCTTGGGGGCATTTTAGCATATGAAATAGCTTCTGGATTAAATATTC
CGGCATTCATTGTAGATCCTGTCGTTGTAGATGAAATGGAGCCGATTGCTCGTATAAGTGGTATTGCTGGTATGGAACGT
AAAAGTATTTTCCATGCATTAAATCAAAAAGCAGTTGCTCGTAAAGTAGCTGAAGAATTAAACCACAAATATGAGGATTT
AAATTTATTAGTTACACATATGGGCGGCGGTATTACAGTTGGTGCTCATAAAAAAGGAAAAGTTATCGATGTGAATAATG
GCTTAAACGGAGAAGGACCATTTAGCCCAGAGCGTGCTGGTACAGTACCAGTAGGACAACTAGTTGAAATGTGTTTCTCT
GGTGAGTATTACCGAGATGAAATGGTTAAAAAACTTGTCGGACAAGGTGGACTTGTAAGTCTTATCGGTACAAATGATGC
GATTAAAGTAGAACAAATGGTTGAAAAAGGTGATCCTGAAGCAACTCTTATTTATAAGGCAATGGCATATCAAGTTGCAA
AAGAGATTGGTGGAGCTAGCGCTGTACTTCACGGGAAAATCGATGCAATCGTATTAACTGGTGGACTTGCTTATAGTAAA
ATTCTTGTTGATGAAATAAAAGAACGAGTAGACTGGATTGCAGATGTTATCGTACATCCAGGAGAAGATGAATTACAAGC
ATTAGCAGAAGGGGCACTTCGTGTACTACGTGAAGAAGAAGCTCCAAAAGAATATATTGTACGTGAAAAAGAAACGGTAG
CTAGGGGTTGA

Upstream 100 bases:

>100_bases
ATACTTACGCAACGGTCACGACATTATTAGCCGTCGCTAATCATTCATATATTACTTTTACAAAAGGTGTGGTTACCTCT
TATGAGGTTTCCACCTCCTT

Downstream 100 bases:

>100_bases
GATAATGGCAAAAGAATATGATTTAGTCATCGTTGGCGGCGGTACTGGTGGATATGTTGCTGCAATTCGTGCATCACAAC
TAGGTTTAAAAACTGCACTT

Product: butyrate kinase

Products: NA

Alternate protein names: BK; Branched-chain carboxylic acid kinase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNLLVEVATVSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLN
AVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMER
KSIFHALNQKAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFS
GEYYRDEMVKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSK
ILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG

Sequences:

>Translated_376_residues
MNLLVEVATVSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLN
AVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMER
KSIFHALNQKAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFS
GEYYRDEMVKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSK
ILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG
>Mature_376_residues
MNLLVEVATVSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLN
AVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMER
KSIFHALNQKAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFS
GEYYRDEMVKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSK
ILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG3426

COG function: function code C; Butyrate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788633, Length=170, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR011245 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.7 [H]

Molecular weight: Translated: 40909; Mature: 40909

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLVEVATVSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEF
CCEEEEEEEEEEEEEEEECCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
RKETILEVLHSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLG
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCC
GILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEEL
CHHHHHHHCCCCCCHHEECCHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
NHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFS
CCHHHHHHEEEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
GEYYRDEMVKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGAS
CCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
AVLHGKIDAIVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEE
EEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
APKEYIVREKETVARG
CCHHHHHCCHHHHCCC
>Mature Secondary Structure
MNLLVEVATVSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEF
CCEEEEEEEEEEEEEEEECCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
RKETILEVLHSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLG
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCC
GILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEEL
CHHHHHHHCCCCCCHHEECCHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
NHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFS
CCHHHHHHEEEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
GEYYRDEMVKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGAS
CCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
AVLHGKIDAIVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEE
EEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
APKEYIVREKETVARG
CCHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA