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The map label for this gene is dinB [H]

Identifier: 118479340

GI number: 118479340

Start: 3970327

End: 3971574

Strand: Reverse

Name: dinB [H]

Synonym: BALH_3757

Alternate gene names: 118479340

Gene position: 3971574-3970327 (Counterclockwise)

Preceding gene: 118479341

Following gene: 118479338

Centisome position: 75.55

GC content: 37.26

Gene sequence:

>1248_bases
GTGAGTACTATGCGAGAAATGTATCCAAAAAAAGGTCGTGTTATTTTACATGTAGATATGAATTGTTTTTTCGCATCTGT
TGAAATTGCTCATGACTCATCATTACAAGGGAAGCCGTTAGCGGTTGCTGGAAATGAAAAAGAAAGAAAAGGAATTATCA
TAACATGTAGTTATGAGGCGAGAGAATATGGAATACGTACAACGATGCCACTTTGGGAAGCGAAAAGGTTATGTCCGCAA
TTAATTGTAAGGCGCCCTAATTTTACATTATATCGCGAAGCTTCATTTCAAATGTTTCAAATTCTTTCCCGTTTTACGGA
AAAAATACAACCAGTCTCTATAGATGAGGGGTATTTAGATATTACAGACTGTTACGCACTTGGTTCACCTCTTGAAATAG
CAAAGATGATTCAGCAGGCGTTATTAACAGAATTGCAGCTTCCGTGTAGCATCGGGATTGCTCCGAACCTTTTCCTAGCA
AAAACAGCTTCTGATATGAAAAAGCCTCTTGGTATTACCGTGCTCCGAAAACGAGATATTCCAGAAATGATTTGGCCACT
TCCGGTTGGAGCGATGCATGGAATTGGAGAAAAAACAGCTGAGAAATTGAATGATATTCATATACAAACCATTGAGCAGT
TAGCAAAAGGAAACGAACATATCATTCGCGCTAAAATTGGAAAGCATGGTGTTGATTTACAAAGGCGGGCAAAAGGTATG
GATGATAGGGAAGTTGATCCGAGTCAAATGGGTCAACATAAAAGTGTTGGTAACTCGATGACTTTTTCAAAGGATATGGA
TGAAGAGAAAGAATTACTTGATATGTTACAAAGGCTATCAAAATCAGTGAGTAAAAGATTACAAAAGCGAACTCTTGTCA
GCTATAATATTCAAATTATGATTAAATATCATGATAGGCGGACAGTAACGAGGAGTAAGCAATTGAAAAATGCCATTTGG
GAAGAACGAGATATTTTTCAAGCAGCCTCTCGTTTATGGAAGCAACATTGGGACGGTGATTCCGTTCGTTTATTAGGTGT
TACAGCTACTGAAATAGAGTGGAAGACTGAATCGGTGAAACAATTAGATTTGTTTTCATTTGAAGAAGATGCGAAAGAAG
AGCCGCTACTTGCTGTCATTGATCAAATTAATGATAAGTATGGAATGCCGCTTTTACAACGAGGTAGTCAATTATTACGT
AAGCAAGAAAAGTCTTTTCAGCAAAAATTAGAAAGTAAGTTTATGTAG

Upstream 100 bases:

>100_bases
ATTTAAATTATAGCAATAAATATGATGGAAAAGAACAAGTAATAATTATAATTATTGTGCAAAATTTGCTATAATAAAAG
AACGAACGTTCTGATTAGGG

Downstream 100 bases:

>100_bases
AAGGTGTCATGAAGCTGTACATATCATGACACTTTTTATTTTTATAAAAAACAAATTGTCGTTTTTGCACTACAAGCAAA
ACAATTATGTAATAACTCAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSTMREMYPKKGRVILHVDMNCFFASVEIAHDSSLQGKPLAVAGNEKERKGIIITCSYEAREYGIRTTMPLWEAKRLCPQ
LIVRRPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITDCYALGSPLEIAKMIQQALLTELQLPCSIGIAPNLFLA
KTASDMKKPLGITVLRKRDIPEMIWPLPVGAMHGIGEKTAEKLNDIHIQTIEQLAKGNEHIIRAKIGKHGVDLQRRAKGM
DDREVDPSQMGQHKSVGNSMTFSKDMDEEKELLDMLQRLSKSVSKRLQKRTLVSYNIQIMIKYHDRRTVTRSKQLKNAIW
EERDIFQAASRLWKQHWDGDSVRLLGVTATEIEWKTESVKQLDLFSFEEDAKEEPLLAVIDQINDKYGMPLLQRGSQLLR
KQEKSFQQKLESKFM

Sequences:

>Translated_415_residues
MSTMREMYPKKGRVILHVDMNCFFASVEIAHDSSLQGKPLAVAGNEKERKGIIITCSYEAREYGIRTTMPLWEAKRLCPQ
LIVRRPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITDCYALGSPLEIAKMIQQALLTELQLPCSIGIAPNLFLA
KTASDMKKPLGITVLRKRDIPEMIWPLPVGAMHGIGEKTAEKLNDIHIQTIEQLAKGNEHIIRAKIGKHGVDLQRRAKGM
DDREVDPSQMGQHKSVGNSMTFSKDMDEEKELLDMLQRLSKSVSKRLQKRTLVSYNIQIMIKYHDRRTVTRSKQLKNAIW
EERDIFQAASRLWKQHWDGDSVRLLGVTATEIEWKTESVKQLDLFSFEEDAKEEPLLAVIDQINDKYGMPLLQRGSQLLR
KQEKSFQQKLESKFM
>Mature_414_residues
STMREMYPKKGRVILHVDMNCFFASVEIAHDSSLQGKPLAVAGNEKERKGIIITCSYEAREYGIRTTMPLWEAKRLCPQL
IVRRPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLDITDCYALGSPLEIAKMIQQALLTELQLPCSIGIAPNLFLAK
TASDMKKPLGITVLRKRDIPEMIWPLPVGAMHGIGEKTAEKLNDIHIQTIEQLAKGNEHIIRAKIGKHGVDLQRRAKGMD
DREVDPSQMGQHKSVGNSMTFSKDMDEEKELLDMLQRLSKSVSKRLQKRTLVSYNIQIMIKYHDRRTVTRSKQLKNAIWE
ERDIFQAASRLWKQHWDGDSVRLLGVTATEIEWKTESVKQLDLFSFEEDAKEEPLLAVIDQINDKYGMPLLQRGSQLLRK
QEKSFQQKLESKFM

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=333, Percent_Identity=28.2282282282282, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI7706681, Length=334, Percent_Identity=28.1437125748503, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI154350220, Length=330, Percent_Identity=27.2727272727273, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI7705344, Length=111, Percent_Identity=40.5405405405405, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI5729982, Length=124, Percent_Identity=41.1290322580645, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=35.3276353276353, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1787432, Length=417, Percent_Identity=24.7002398081535, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17537959, Length=300, Percent_Identity=24.6666666666667, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI115534089, Length=122, Percent_Identity=35.2459016393443, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193205700, Length=115, Percent_Identity=31.304347826087, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19923006, Length=352, Percent_Identity=28.9772727272727, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI21355641, Length=348, Percent_Identity=27.2988505747126, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644984, Length=348, Percent_Identity=27.2988505747126, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24668444, Length=133, Percent_Identity=39.0977443609023, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 47770; Mature: 47639

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMREMYPKKGRVILHVDMNCFFASVEIAHDSSLQGKPLAVAGNEKERKGIIITCSYEA
CCCHHHHCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECHH
REYGIRTTMPLWEAKRLCPQLIVRRPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLD
HHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEE
ITDCYALGSPLEIAKMIQQALLTELQLPCSIGIAPNLFLAKTASDMKKPLGITVLRKRDI
HHHHHHCCCHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHCHHHHHCCCCEEEEECCCC
PEMIWPLPVGAMHGIGEKTAEKLNDIHIQTIEQLAKGNEHIIRAKIGKHGVDLQRRAKGM
HHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCC
DDREVDPSQMGQHKSVGNSMTFSKDMDEEKELLDMLQRLSKSVSKRLQKRTLVSYNIQIM
CCCCCCHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
IKYHDRRTVTRSKQLKNAIWEERDIFQAASRLWKQHWDGDSVRLLGVTATEIEWKTESVK
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECHHHHH
QLDLFSFEEDAKEEPLLAVIDQINDKYGMPLLQRGSQLLRKQEKSFQQKLESKFM
HHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STMREMYPKKGRVILHVDMNCFFASVEIAHDSSLQGKPLAVAGNEKERKGIIITCSYEA
CCHHHHCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECHH
REYGIRTTMPLWEAKRLCPQLIVRRPNFTLYREASFQMFQILSRFTEKIQPVSIDEGYLD
HHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEE
ITDCYALGSPLEIAKMIQQALLTELQLPCSIGIAPNLFLAKTASDMKKPLGITVLRKRDI
HHHHHHCCCHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHCHHHHHCCCCEEEEECCCC
PEMIWPLPVGAMHGIGEKTAEKLNDIHIQTIEQLAKGNEHIIRAKIGKHGVDLQRRAKGM
HHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCC
DDREVDPSQMGQHKSVGNSMTFSKDMDEEKELLDMLQRLSKSVSKRLQKRTLVSYNIQIM
CCCCCCHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
IKYHDRRTVTRSKQLKNAIWEERDIFQAASRLWKQHWDGDSVRLLGVTATEIEWKTESVK
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECHHHHH
QLDLFSFEEDAKEEPLLAVIDQINDKYGMPLLQRGSQLLRKQEKSFQQKLESKFM
HHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]