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The map label for this gene is lolS [H]

Identifier: 118479298

GI number: 118479298

Start: 3929261

End: 3930175

Strand: Direct

Name: lolS [H]

Synonym: BALH_3713

Alternate gene names: 118479298

Gene position: 3929261-3930175 (Clockwise)

Preceding gene: 118479296

Following gene: 118479302

Centisome position: 74.74

GC content: 36.28

Gene sequence:

>915_bases
ATGAAAAAACGTCAATTAGGAAACTCAGATTTATTTGTGACAGAAATGGGACTTGGCTGTATGTCTCTCGGTACATCTGA
AACAGAAGCCCTGCGTATTGTCGATGAAGCAATCGATTTAGGAATCAATTTTTTTGATACAGCAGATTTATATGATTATG
GATTAAACGAAGAATTTGTTGGAAAAGCCTTAAAAGGGAAACGAGACCAAATTATTCTTACAACAAAGGTTGGAAATCGA
TGGACAGAAGAAAAAAATGGCTGGTCTTGGGACCCTTCTAAAAATTACATAAAGGCTGAAGTGAAGGAAAGTTTACGTAG
ACTTCAAACTGATTATATTGATCTTTATCAACTTCATGGCGGAACGATTGAAGATCCTATAGATGAAACAATTGAAGCCT
TTGAAGAATTAAAAAAAGAAGGTATCATTCGCCATTACGGTATTTCTTCTATACGTCCAAATGTCATCCGTGAGTATGCA
AAACGTTCAAATATCGTTAGTGTACTAATGGAATATAGCCTTTTAAATCGTCGCCCTGAAGAATGGTTCCCGCTTCTTAA
TGAACATCAAATTAGCGTCATTGCCCGCGGACCGCTTGCAAAAGGAATTCTAACTGACAACAATGCAAGAAAGATAGAAA
GAGTAAAAGAAAAGGATTACCTTTCTTATTCTTACGATGAATTATATGAGACACTCGCGGGTGTAAAAGAATTAATTAGG
GAAAGCTCTTTAACAGGAACAGCTATTCAATATTGCTTACATAACGACACTGTAGCAGCTGTAATACCTGGTGCAAGCTC
TATTGGGCAATTACGAGAAAATGTACAGGCTAGTAAACAAACACAGTTAACAACAGAAGAATATATACAGCTTCAGCAAA
TTGCGAAATGTGATACGTACGCTTTACATCGTTAA

Upstream 100 bases:

>100_bases
AAGAGTATACAACTGTACAAGAGTGGATTACAGCTAGTAAAAAGTAAAAGTTTGTCAACCTCTTTTCCCTTTCGTACAAT
AAGAGTAAGGAGGTTGACCT

Downstream 100 bases:

>100_bases
AAAGACGCTACCATACTGGTAGCGTCTTTTTATAACGTATCATATTTATCAGGATTCGTTCCTACATGTAAATTACGATT
TAACGTATTAATTTGAGTCA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSETEALRIVDEAIDLGINFFDTADLYDYGLNEEFVGKALKGKRDQIILTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYETLAGVKELIR
ESSLTGTAIQYCLHNDTVAAVIPGASSIGQLRENVQASKQTQLTTEEYIQLQQIAKCDTYALHR

Sequences:

>Translated_304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSETEALRIVDEAIDLGINFFDTADLYDYGLNEEFVGKALKGKRDQIILTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYETLAGVKELIR
ESSLTGTAIQYCLHNDTVAAVIPGASSIGQLRENVQASKQTQLTTEEYIQLQQIAKCDTYALHR
>Mature_304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSETEALRIVDEAIDLGINFFDTADLYDYGLNEEFVGKALKGKRDQIILTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYETLAGVKELIR
ESSLTGTAIQYCLHNDTVAAVIPGASSIGQLRENVQASKQTQLTTEEYIQLQQIAKCDTYALHR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=310, Percent_Identity=30, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI4504825, Length=307, Percent_Identity=29.9674267100977, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27436964, Length=306, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI27436966, Length=306, Percent_Identity=29.0849673202614, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436962, Length=306, Percent_Identity=29.0849673202614, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=27.4143302180685, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI223718702, Length=300, Percent_Identity=26.3333333333333, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=31.8181818181818, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788070, Length=306, Percent_Identity=30.718954248366, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=25.8720930232558, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789375, Length=321, Percent_Identity=28.9719626168224, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787674, Length=283, Percent_Identity=25.7950530035336, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788081, Length=295, Percent_Identity=26.7796610169492, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082198, Length=215, Percent_Identity=28.3720930232558, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786400, Length=202, Percent_Identity=30.6930693069307, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994888, Length=296, Percent_Identity=22.2972972972973, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=304, Percent_Identity=26.3157894736842, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=27.6470588235294, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25.3378378378378, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646155, Length=273, Percent_Identity=28.9377289377289, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640980, Length=338, Percent_Identity=24.8520710059172, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45549126, Length=338, Percent_Identity=24.8520710059172, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34709; Mature: 34709

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRQLGNSDLFVTEMGLGCMSLGTSETEALRIVDEAIDLGINFFDTADLYDYGLNEEFV
CCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHH
GKALKGKRDQIILTTKVGNRWTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHG
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYAKRSNIVSVLMEYSLLNRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYETLAGVKELIR
HHHCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ESSLTGTAIQYCLHNDTVAAVIPGASSIGQLRENVQASKQTQLTTEEYIQLQQIAKCDTY
HCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALHR
HCCC
>Mature Secondary Structure
MKKRQLGNSDLFVTEMGLGCMSLGTSETEALRIVDEAIDLGINFFDTADLYDYGLNEEFV
CCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHH
GKALKGKRDQIILTTKVGNRWTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHG
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYAKRSNIVSVLMEYSLLNRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYETLAGVKELIR
HHHCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ESSLTGTAIQYCLHNDTVAAVIPGASSIGQLRENVQASKQTQLTTEEYIQLQQIAKCDTY
HCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALHR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]