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The map label for this gene is mtnE [H]

Identifier: 118479240

GI number: 118479240

Start: 3878044

End: 3879216

Strand: Direct

Name: mtnE [H]

Synonym: BALH_3652

Alternate gene names: 118479240

Gene position: 3878044-3879216 (Clockwise)

Preceding gene: 118479236

Following gene: 118479241

Centisome position: 73.77

GC content: 37.25

Gene sequence:

>1173_bases
ATGAAATTATTTCAACCTTCTGAGATAGTAACATCATTGCCAACACAATTTTTTGCTTCACTTGTTGCAAAAGTTAATAA
AGTCGTTGCAGCTGGTCACGATGTTATTAATCTAGGTCAAGGTAATCCAGATCAACCAACGCCGCAGCATATCGTAAAAG
CTTTACAAGATGCTGCAGAAAAGACCATTCATCATAAATATCCGCCATTTCGCGGACATGAAAGTTTAAAAGAAGCCGTG
GCAACATTCTATCAACGTGAATATGATGTAGTAGTAAATCCAAAAACTGAAGTTGCTATTTTGTTTGGTGGAAAGGCTGG
ATTAGTAGAATTACCAGTTTGTTTTACAAACCCTGGTGATACGATTCTCGTTCCTGATCCAGGCTATCCAGATTATTTAT
CAGGAGTTGCTTTAGCAAAAGCACAATTTGAAACAATGCCGCTTATTGCAGAAAATAATTTTTTACCAGATTATACGAAA
ATCGATGACTCTATTGCCGAGCGTGCAAAATTAATGTTTTTAAACTATCCAAATAATCCGACCGGTGCTACTGCATCAAA
AGATTTCTTTGATGAAACCATTCATTTTGCTAATAAACATAATATATTAGTCGTTCATGATTTTGCTTACGGTGCGATTG
GATTCGATGGTCAAAAACCTGTTAGTTTCTTACAAGCAGATGGTGCCAAAGATACAGGAATCGAAATTTACACCTTATCG
AAAACTTTCAATATGGCTGGCTGGCGCATCGCTTTTGCGGTAGGGAATGAAAGTGTGATTGAAACAATTAACTTATTACA
AGATCATATGTATGTTAGTATTTTTGGTGCCATTCAAGATGCTGCCCGCGAAGCACTATTAAGTTCACAGTCTTGCGTCA
TAGACCTTGTAAATAGTTACGAATCTCGAAGAAACGCTCTTATTTCAGCTTGTCACTCAATTGGTTGGAATGTAGACATT
CCAACAGGATCATTCTTTGCATGGCTTCCTGTTCCAGAAGGTTATACATCTGAGCAATTTTCTGATATTTTACTAGAAAA
AGCACACGTTGCGGTTGCTCCTGGTGTTGGATTTGGTGAACATGGCGAAGGGTACGTCCGTGTTGGTCTCTTGCATACAG
AAGATAGATTACGAGAAGCCATTAATCGAATTGATAAATTAAATTTTTTTTAA

Upstream 100 bases:

>100_bases
ATTTTTTCAGCCCCATTCTCATTTTTTTCTTTACAAAATACTGGAAAGATTATATCATTTGTCACTAGAATTGTAACAAC
TTTCAAAAGAGGTGGAAAGT

Downstream 100 bases:

>100_bases
AAGTAATTGACAACATGAAAAATATCTGACAAAATTCAGTTATCTTAAAAATTTAAACATTTCTAAATACTTCTTATCAA
GAGCAGGTGGAGGGACGAGC

Product: transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKLFQPSEIVTSLPTQFFASLVAKVNKVVAAGHDVINLGQGNPDQPTPQHIVKALQDAAEKTIHHKYPPFRGHESLKEAV
ATFYQREYDVVVNPKTEVAILFGGKAGLVELPVCFTNPGDTILVPDPGYPDYLSGVALAKAQFETMPLIAENNFLPDYTK
IDDSIAERAKLMFLNYPNNPTGATASKDFFDETIHFANKHNILVVHDFAYGAIGFDGQKPVSFLQADGAKDTGIEIYTLS
KTFNMAGWRIAFAVGNESVIETINLLQDHMYVSIFGAIQDAAREALLSSQSCVIDLVNSYESRRNALISACHSIGWNVDI
PTGSFFAWLPVPEGYTSEQFSDILLEKAHVAVAPGVGFGEHGEGYVRVGLLHTEDRLREAINRIDKLNFF

Sequences:

>Translated_390_residues
MKLFQPSEIVTSLPTQFFASLVAKVNKVVAAGHDVINLGQGNPDQPTPQHIVKALQDAAEKTIHHKYPPFRGHESLKEAV
ATFYQREYDVVVNPKTEVAILFGGKAGLVELPVCFTNPGDTILVPDPGYPDYLSGVALAKAQFETMPLIAENNFLPDYTK
IDDSIAERAKLMFLNYPNNPTGATASKDFFDETIHFANKHNILVVHDFAYGAIGFDGQKPVSFLQADGAKDTGIEIYTLS
KTFNMAGWRIAFAVGNESVIETINLLQDHMYVSIFGAIQDAAREALLSSQSCVIDLVNSYESRRNALISACHSIGWNVDI
PTGSFFAWLPVPEGYTSEQFSDILLEKAHVAVAPGVGFGEHGEGYVRVGLLHTEDRLREAINRIDKLNFF
>Mature_390_residues
MKLFQPSEIVTSLPTQFFASLVAKVNKVVAAGHDVINLGQGNPDQPTPQHIVKALQDAAEKTIHHKYPPFRGHESLKEAV
ATFYQREYDVVVNPKTEVAILFGGKAGLVELPVCFTNPGDTILVPDPGYPDYLSGVALAKAQFETMPLIAENNFLPDYTK
IDDSIAERAKLMFLNYPNNPTGATASKDFFDETIHFANKHNILVVHDFAYGAIGFDGQKPVSFLQADGAKDTGIEIYTLS
KTFNMAGWRIAFAVGNESVIETINLLQDHMYVSIFGAIQDAAREALLSSQSCVIDLVNSYESRRNALISACHSIGWNVDI
PTGSFFAWLPVPEGYTSEQFSDILLEKAHVAVAPGVGFGEHGEGYVRVGLLHTEDRLREAINRIDKLNFF

Specific function: Catalyzes the formation of methionine from 2-keto-4- methylthiobutyrate (KMTB) (Probable) [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. MtnE subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=316, Percent_Identity=24.6835443037975, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI169881279, Length=316, Percent_Identity=24.6835443037975, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI56713256, Length=314, Percent_Identity=22.6114649681529, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI56713254, Length=314, Percent_Identity=22.6114649681529, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI169881281, Length=305, Percent_Identity=23.2786885245902, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788722, Length=359, Percent_Identity=37.883008356546, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1786816, Length=392, Percent_Identity=23.2142857142857, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788627, Length=244, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=363, Percent_Identity=26.4462809917355, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=363, Percent_Identity=26.4462809917355, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17567369, Length=267, Percent_Identity=23.5955056179775, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=391, Percent_Identity=22.7621483375959, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=235, Percent_Identity=23.4042553191489, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573069, Length=410, Percent_Identity=22.6829268292683, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646114, Length=410, Percent_Identity=22.6829268292683, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573067, Length=410, Percent_Identity=22.6829268292683, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573065, Length=410, Percent_Identity=22.6829268292683, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI18859735, Length=359, Percent_Identity=23.6768802228412, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42894; Mature: 42894

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFQPSEIVTSLPTQFFASLVAKVNKVVAAGHDVINLGQGNPDQPTPQHIVKALQDAAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
KTIHHKYPPFRGHESLKEAVATFYQREYDVVVNPKTEVAILFGGKAGLVELPVCFTNPGD
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEEEEEEEECCCC
TILVPDPGYPDYLSGVALAKAQFETMPLIAENNFLPDYTKIDDSIAERAKLMFLNYPNNP
EEEECCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCC
TGATASKDFFDETIHFANKHNILVVHDFAYGAIGFDGQKPVSFLQADGAKDTGIEIYTLS
CCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCHHHHHCCCCCCCCEEEEEEE
KTFNMAGWRIAFAVGNESVIETINLLQDHMYVSIFGAIQDAAREALLSSQSCVIDLVNSY
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ESRRNALISACHSIGWNVDIPTGSFFAWLPVPEGYTSEQFSDILLEKAHVAVAPGVGFGE
HHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCC
HGEGYVRVGLLHTEDRLREAINRIDKLNFF
CCCCEEEEEEEECHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLFQPSEIVTSLPTQFFASLVAKVNKVVAAGHDVINLGQGNPDQPTPQHIVKALQDAAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
KTIHHKYPPFRGHESLKEAVATFYQREYDVVVNPKTEVAILFGGKAGLVELPVCFTNPGD
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEEEEEEEECCCC
TILVPDPGYPDYLSGVALAKAQFETMPLIAENNFLPDYTKIDDSIAERAKLMFLNYPNNP
EEEECCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCC
TGATASKDFFDETIHFANKHNILVVHDFAYGAIGFDGQKPVSFLQADGAKDTGIEIYTLS
CCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCHHHHHCCCCCCCCEEEEEEE
KTFNMAGWRIAFAVGNESVIETINLLQDHMYVSIFGAIQDAAREALLSSQSCVIDLVNSY
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ESRRNALISACHSIGWNVDIPTGSFFAWLPVPEGYTSEQFSDILLEKAHVAVAPGVGFGE
HHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCC
HGEGYVRVGLLHTEDRLREAINRIDKLNFF
CCCCEEEEEEEECHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]