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The map label for this gene is carA [H]

Identifier: 118479108

GI number: 118479108

Start: 3736417

End: 3737538

Strand: Reverse

Name: carA [H]

Synonym: BALH_3517

Alternate gene names: 118479108

Gene position: 3737538-3736417 (Counterclockwise)

Preceding gene: 118479109

Following gene: 118479107

Centisome position: 71.1

GC content: 37.43

Gene sequence:

>1122_bases
ATGGCAAAAGGAGAGTGCATTAGTATGAAAAGACAACTTATCTTAGAAGATGGAACAGTATTAATTGGAACAGGTTTCGG
AGGAGAAATCGAAAAGTCAGGTGAGGTTGTATTTACAACAGGAATGACTGGATATCAAGAAACATTATCTGATCCATCAT
ATTGCGGTCAAATTGTAACATTCACGTACCCATTAATCGGAAACTACGGCATCAACCGTGACGATTTTGAATCGATTCAC
CCATCTGTAAATGGTTTAATCGTAAACGAAATTTGTGATCACCCATCTAACTTCCGTAATGAAATTTCGTTAAATGACTA
CTTAAAAGAAAGAAACATCCCAGGATTAGCAGGGATTGATACGAGAAAATTAACGAGAAAAATTCGTCAATACGGTACAT
TACGCGGACGCCTTTGTAACATGGATGCAGATGTAGAGTACATTGTAAGCCAATTAAAAGCGACAGTATTTACAGATCAT
GTAAAACGCGTATCAACGAAAGATCCATACCCAAGCCCAGGTCGTGGTCACCGAGTTGTACTAGTAGACTTCGGTATGAA
ACATGGTATTTTACGAGAATTAAATAAGCGTGACTGTGATGTAATTGTAGTTCCTTACAACACAACAGCAGAAGAAATTT
TACGCCTTAGTCCAGATGGAATTATGTTAAGTAACGGACCTGGAGATCCGAAAGATGTACCAGAAGCAATTGAAATGTTA
AAAGACATTATCGGTAAAGTTCCTTTATTCGGAATTTGCCTAGGACATCAATTGTTCGCTCTAGCATCTGGTGCGAATAC
AAGTAAGTTAAAATTCGGTCACCGTGGTTTAAACCATCCGGTAAAAAATATTGCAACTGGAAAAGTAGCAATTACATCTC
AAAATCATGGTTACGCAGTAGAAGAAGAATCAGTTGAAAATACAGAACTTGAAATTACACATGTTGCTTTAAATGATGGA
ACAGTAGAAGGTCTTCGTCATAAGAAGTTTCCAGCATTTACAGTTCAATACCATCCAGAAGCTTCAGCAGGACCAGAAGA
TGCAAATGATTTATTCGAAGATTTCTTAACAATGATTGAAAACTTCAAGAAAGAAGGGGAAGAGTTATGCCAAAACGCCT
AG

Upstream 100 bases:

>100_bases
TTGACCCAACAACATTCTTATCAAAAGGAAAAAACACACCATTCGCAGGTTGGAAATGCCAAGGATGGCCGGTAATGACA
ATCGTTGGTGGTAAGATCGC

Downstream 100 bases:

>100_bases
ACATTAACACAATTTTAGTAATCGGATCAGGACCAATTGTAATTGGGCAAGCAGCGGAGTTTGACTACTCTGGTACACAA
GCTTGTCAATCTCTTAAAGA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MAKGECISMKRQLILEDGTVLIGTGFGGEIEKSGEVVFTTGMTGYQETLSDPSYCGQIVTFTYPLIGNYGINRDDFESIH
PSVNGLIVNEICDHPSNFRNEISLNDYLKERNIPGLAGIDTRKLTRKIRQYGTLRGRLCNMDADVEYIVSQLKATVFTDH
VKRVSTKDPYPSPGRGHRVVLVDFGMKHGILRELNKRDCDVIVVPYNTTAEEILRLSPDGIMLSNGPGDPKDVPEAIEML
KDIIGKVPLFGICLGHQLFALASGANTSKLKFGHRGLNHPVKNIATGKVAITSQNHGYAVEEESVENTELEITHVALNDG
TVEGLRHKKFPAFTVQYHPEASAGPEDANDLFEDFLTMIENFKKEGEELCQNA

Sequences:

>Translated_373_residues
MAKGECISMKRQLILEDGTVLIGTGFGGEIEKSGEVVFTTGMTGYQETLSDPSYCGQIVTFTYPLIGNYGINRDDFESIH
PSVNGLIVNEICDHPSNFRNEISLNDYLKERNIPGLAGIDTRKLTRKIRQYGTLRGRLCNMDADVEYIVSQLKATVFTDH
VKRVSTKDPYPSPGRGHRVVLVDFGMKHGILRELNKRDCDVIVVPYNTTAEEILRLSPDGIMLSNGPGDPKDVPEAIEML
KDIIGKVPLFGICLGHQLFALASGANTSKLKFGHRGLNHPVKNIATGKVAITSQNHGYAVEEESVENTELEITHVALNDG
TVEGLRHKKFPAFTVQYHPEASAGPEDANDLFEDFLTMIENFKKEGEELCQNA
>Mature_372_residues
AKGECISMKRQLILEDGTVLIGTGFGGEIEKSGEVVFTTGMTGYQETLSDPSYCGQIVTFTYPLIGNYGINRDDFESIHP
SVNGLIVNEICDHPSNFRNEISLNDYLKERNIPGLAGIDTRKLTRKIRQYGTLRGRLCNMDADVEYIVSQLKATVFTDHV
KRVSTKDPYPSPGRGHRVVLVDFGMKHGILRELNKRDCDVIVVPYNTTAEEILRLSPDGIMLSNGPGDPKDVPEAIEMLK
DIIGKVPLFGICLGHQLFALASGANTSKLKFGHRGLNHPVKNIATGKVAITSQNHGYAVEEESVENTELEITHVALNDGT
VEGLRHKKFPAFTVQYHPEASAGPEDANDLFEDFLTMIENFKKEGEELCQNA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=366, Percent_Identity=41.5300546448087, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI21361331, Length=375, Percent_Identity=36.2666666666667, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI169790915, Length=375, Percent_Identity=36.2666666666667, Blast_Score=216, Evalue=3e-56,
Organism=Escherichia coli, GI1786215, Length=379, Percent_Identity=45.646437994723, Blast_Score=306, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI193204318, Length=371, Percent_Identity=40.1617250673854, Blast_Score=254, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6324878, Length=379, Percent_Identity=39.0501319261214, Blast_Score=262, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6322331, Length=392, Percent_Identity=37.7551020408163, Blast_Score=255, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6322638, Length=152, Percent_Identity=34.2105263157895, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45555749, Length=389, Percent_Identity=39.8457583547558, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24642586, Length=389, Percent_Identity=39.8457583547558, Blast_Score=258, Evalue=5e-69,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41197; Mature: 41066

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGECISMKRQLILEDGTVLIGTGFGGEIEKSGEVVFTTGMTGYQETLSDPSYCGQIVT
CCCCHHHHHHHHHEEECCCEEEECCCCCCCCCCCCEEEEECCCCHHHHCCCHHHCCEEEE
FTYPLIGNYGINRDDFESIHPSVNGLIVNEICDHPSNFRNEISLNDYLKERNIPGLAGID
EEEHHHCCCCCCHHHHHHHCCCCCCEEHHHHHCCCCCHHCCCCHHHHHHHCCCCCCCCCC
TRKLTRKIRQYGTLRGRLCNMDADVEYIVSQLKATVFTDHVKRVSTKDPYPSPGRGHRVV
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
LVDFGMKHGILRELNKRDCDVIVVPYNTTAEEILRLSPDGIMLSNGPGDPKDVPEAIEML
EEECCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
KDIIGKVPLFGICLGHQLFALASGANTSKLKFGHRGLNHPVKNIATGKVAITSQNHGYAV
HHHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHCCCCEEEEEECCCCCEE
EEESVENTELEITHVALNDGTVEGLRHKKFPAFTVQYHPEASAGPEDANDLFEDFLTMIE
CCCCCCCCEEEEEEEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
NFKKEGEELCQNA
HHHHHHHHHHCCC
>Mature Secondary Structure 
AKGECISMKRQLILEDGTVLIGTGFGGEIEKSGEVVFTTGMTGYQETLSDPSYCGQIVT
CCCHHHHHHHHHEEECCCEEEECCCCCCCCCCCCEEEEECCCCHHHHCCCHHHCCEEEE
FTYPLIGNYGINRDDFESIHPSVNGLIVNEICDHPSNFRNEISLNDYLKERNIPGLAGID
EEEHHHCCCCCCHHHHHHHCCCCCCEEHHHHHCCCCCHHCCCCHHHHHHHCCCCCCCCCC
TRKLTRKIRQYGTLRGRLCNMDADVEYIVSQLKATVFTDHVKRVSTKDPYPSPGRGHRVV
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
LVDFGMKHGILRELNKRDCDVIVVPYNTTAEEILRLSPDGIMLSNGPGDPKDVPEAIEML
EEECCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
KDIIGKVPLFGICLGHQLFALASGANTSKLKFGHRGLNHPVKNIATGKVAITSQNHGYAV
HHHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHCCCCEEEEEECCCCCEE
EEESVENTELEITHVALNDGTVEGLRHKKFPAFTVQYHPEASAGPEDANDLFEDFLTMIE
CCCCCCCCEEEEEEEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
NFKKEGEELCQNA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]