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The map label for this gene is prpC [H]

Identifier: 118479085

GI number: 118479085

Start: 3708885

End: 3709715

Strand: Reverse

Name: prpC [H]

Synonym: BALH_3494

Alternate gene names: 118479085

Gene position: 3709715-3708885 (Counterclockwise)

Preceding gene: 118479086

Following gene: 118479084

Centisome position: 70.57

GC content: 39.23

Gene sequence:

>831_bases
GTGAACAAGGTCATGATATTGATGCAGCCTGCGGTCAGTTGCGTGCGAAGGAGCGCAAAGAAGAGACGAGGTGACGAGAT
GAAAGCCGTGTTTCTATCAGATAAAGGAAAAGTTCGTCAACATAATGAAGATAGTGCAGGAGTTTTTCACAATTTAGATG
GAAATATTTTAGCGGTAGTAGCAGATGGAATGGGAGGTCATCGAGCTGGTGATGTAGCGAGCTCGATGACCATTCAATTA
TTCCATGATTATTGGAAGCAAACGCATAATATGAATGAGCCAAAAAAAGTAGAAGAGTGGTTACATACTAGTGTTGGGAT
AATTAATGAGCGTATATATGAGTACTCTAAGCAACATGTAGAATGTAATGGTATGGGAACAACACTTATAATAGCAATTT
GTACGCCGAGCTTTGTGACAATAGGTCATATAGGGGATAGTCGTTGTTATATGGTATCAGAGGGAGAAATCTCGCTTGTA
ACGGAAGATCACTCACTTGTAAATGAACTTGTGAGACATGGTGAAATTTCAAAAGAAGACGCAGAATATCACCCGAAAAA
GAATGTTTTATTAAGGGCATTAGGAACAGAAGAGAGAGTTGGATTAGATGTTAAAACATTGGTGCTAGAGGAAGATGATC
AGCTACTTCTTTGCTCTGATGGATTATCTAACAAAGTTTCTATTGCTGATATGCAACAAATTTTACAGTTAAATGAACAG
CTAGAAACTAAGGGACAACGTCTCATTCAATTGGCGAATGATCGTGGCGGGGAAGATAATATCACCCTTGTTCTGATTGA
TTATGCGGGTTCGACAAACGAAAGTAGGTGA

Upstream 100 bases:

>100_bases
AACTACGTACCTGAACGTGATTATGTACGTACGCCACGTGAACAAATTTTCCTATTTGAAAAAACGTTGAAAGATCGTGG
GGTAAATGTAACGATTCGCC

Downstream 100 bases:

>100_bases
AGTGCAACGTGCTGATTGGAAAACGCTTAAATGACCGTTATAAGCTGCTGAAAATGATTGGTGGCGGTGGAATGGCCAAT
GTGTATTTAGCTCATGATGA

Product: protein phosphatase 2C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNKVMILMQPAVSCVRRSAKKRRGDEMKAVFLSDKGKVRQHNEDSAGVFHNLDGNILAVVADGMGGHRAGDVASSMTIQL
FHDYWKQTHNMNEPKKVEEWLHTSVGIINERIYEYSKQHVECNGMGTTLIIAICTPSFVTIGHIGDSRCYMVSEGEISLV
TEDHSLVNELVRHGEISKEDAEYHPKKNVLLRALGTEERVGLDVKTLVLEEDDQLLLCSDGLSNKVSIADMQQILQLNEQ
LETKGQRLIQLANDRGGEDNITLVLIDYAGSTNESR

Sequences:

>Translated_276_residues
MNKVMILMQPAVSCVRRSAKKRRGDEMKAVFLSDKGKVRQHNEDSAGVFHNLDGNILAVVADGMGGHRAGDVASSMTIQL
FHDYWKQTHNMNEPKKVEEWLHTSVGIINERIYEYSKQHVECNGMGTTLIIAICTPSFVTIGHIGDSRCYMVSEGEISLV
TEDHSLVNELVRHGEISKEDAEYHPKKNVLLRALGTEERVGLDVKTLVLEEDDQLLLCSDGLSNKVSIADMQQILQLNEQ
LETKGQRLIQLANDRGGEDNITLVLIDYAGSTNESR
>Mature_276_residues
MNKVMILMQPAVSCVRRSAKKRRGDEMKAVFLSDKGKVRQHNEDSAGVFHNLDGNILAVVADGMGGHRAGDVASSMTIQL
FHDYWKQTHNMNEPKKVEEWLHTSVGIINERIYEYSKQHVECNGMGTTLIIAICTPSFVTIGHIGDSRCYMVSEGEISLV
TEDHSLVNELVRHGEISKEDAEYHPKKNVLLRALGTEERVGLDVKTLVLEEDDQLLLCSDGLSNKVSIADMQQILQLNEQ
LETKGQRLIQLANDRGGEDNITLVLIDYAGSTNESR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 30802; Mature: 30802

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVMILMQPAVSCVRRSAKKRRGDEMKAVFLSDKGKVRQHNEDSAGVFHNLDGNILAVV
CCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEE
ADGMGGHRAGDVASSMTIQLFHDYWKQTHNMNEPKKVEEWLHTSVGIINERIYEYSKQHV
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
ECNGMGTTLIIAICTPSFVTIGHIGDSRCYMVSEGEISLVTEDHSLVNELVRHGEISKED
EECCCCCEEEEEEECCCEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCCC
AEYHPKKNVLLRALGTEERVGLDVKTLVLEEDDQLLLCSDGLSNKVSIADMQQILQLNEQ
CCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEEHHHHHHHHHHHHH
LETKGQRLIQLANDRGGEDNITLVLIDYAGSTNESR
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MNKVMILMQPAVSCVRRSAKKRRGDEMKAVFLSDKGKVRQHNEDSAGVFHNLDGNILAVV
CCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEE
ADGMGGHRAGDVASSMTIQLFHDYWKQTHNMNEPKKVEEWLHTSVGIINERIYEYSKQHV
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
ECNGMGTTLIIAICTPSFVTIGHIGDSRCYMVSEGEISLVTEDHSLVNELVRHGEISKED
EECCCCCEEEEEEECCCEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCCC
AEYHPKKNVLLRALGTEERVGLDVKTLVLEEDDQLLLCSDGLSNKVSIADMQQILQLNEQ
CCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEEHHHHHHHHHHHHH
LETKGQRLIQLANDRGGEDNITLVLIDYAGSTNESR
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]