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The map label for this gene is ltrA [H]

Identifier: 118479039

GI number: 118479039

Start: 3657729

End: 3659555

Strand: Reverse

Name: ltrA [H]

Synonym: BALH_3447

Alternate gene names: 118479039

Gene position: 3659555-3657729 (Counterclockwise)

Preceding gene: 118479040

Following gene: 118479038

Centisome position: 69.61

GC content: 33.33

Gene sequence:

>1827_bases
TTGGCTGACTTGATGATTCAAAAGTTAAGAAACAATGAATATTTTGGCTTACAATCAACTTTTGACAATCTTTATGAAGA
AAGCAAAAAGGGTCGATATTTCAAAAATATTTATGAGCTGATTATTTCTGAAGAAAACATTCGATTAGCCTTTCGTAATT
TAAAAAGCAACATAGGTAGTAAAACGAAAGGGACAAATGGTCACACAATAAAACATCTTAATAAAATAGATGCCGACAAG
CTAATTAGATTAACGCAGAAGAGATTGGAAAACTATATGCCGCATGCAGTAAGGCGTTTGTTTATATCAAAGCCAAATGG
AAAAATGCGACCTTTAGGGATTCCAACAATTGAAGACCGATTAATCCAGCAAATGTTCCAACAAGTTCTAGAGCCGATTG
TTGAAGGGAAGTTCCATCCACAAAGCTATGGTTTTCGACCAAAACGCGGCACTCATGATGCTTTAGCTAGATGCTATCAT
ATGGTTAATCACAGTCATCAACATTTTGTAGTGGACATAGATATTAAAGGTTTCTTTGATAACGTTAATCATAAAAAGCT
AATGAGGCAACTATGGACAATTGGAATACGGGATAAAAAAGTTTTATCCATTATCAAAAAGATGCTGAAGGCGGAAGTTA
CAGGTGAAGGCATTCCTGTTAAAGGGACTCCTCAAGGTGGTATTTTATCTCCATTACTAGCCAACGTTGTATTAAATGAA
CTTGACTGGTGGGTGTCAAACCAATGGGAAACAAAGCCGACAAGAGTACCTTATAAATTAAAACGCAATAAAACGGATGC
GCTAAAAAAGACAAGGTTAAAGCCAATGTATCTAGTAAGGTATGCAGATGATTTTAAAATCTTCACAAATTCCTACGATA
ACGCTAGAAAGATTAAAATAGCGGTTGAAAAATGGCTCAAAGAAAGATTGGGTCTTGAGATAAGTGAAGAAAAAAGTAAA
ATCACAAACTTACGGAAAAACGGTACAGATTTTTTAGGGATTCGATTTAGAGCAGTTCAGAAGGGGAATGCTAAAACTGG
TTATATTGTAAATTCTAAAATGGACCCGAAAGCGAAAGATAAAGTATTGGGTGTCATTAGGCATCAACTAGTGAAACTAA
GAAAAAGTCCCACTCCAGAAAAAGTGATGAATTTTAATTCGAATATACTTGGGTTGCATAATTACTACAAAATTGCGACC
AGAATCTCTCAAGATTTTAACGAGCTAAGACATAAAATTCATCCGAATATAAAATCATTGATGTTCAGAAACATCTTTGT
TTATACAATAGAAACTAATCATATCATTGATAAGTTTTATGGAGATTATAATTGTCCAAGGTTTAAAAGTAATGGATTAC
TGGTCTATCCTATTGAAGCAATTCGACATGATATACGAGGTCAAAGAGACCCTAATTTTTCTGTTTATAATAAAAAGGAT
AGGGCATCAATTCATAAAGAGATAAAACATGTGTCTGTGCGAGAAATCGAAATGTTTCGTAAAGGAATATATAAAGCAAA
AAGTGTTTTGTATGAAAATAATCGCTTAAGTAAATATGTCGCGCAAAAAGGATGTTGTGGCATAACGGGAGAACGATTAA
CTCCTCATAATGCTATATGTCATCACATTAAGCCAACAGGGCAAGGTGGTAGTGATGAATATCACAACTTGATTATTATT
AATAAGAAATACCATACATTAATTCATAATAAAGACCCTCTTGCAAATGAAGATTATAAAAAAATGTTAGTCAAGCTTGA
AAAGAAAGCATTAAATAAATTAAATAAGTTGAGAACGGAAGTAGGAAATCCAAAACTCAGCTTATAA

Upstream 100 bases:

>100_bases
GAGGGAAGGGCACAAGTCGTTAACGTCGAAACAAAACCTACAAAAGTCAGATTCGTGTATGACAAAAGAGAAACGAAAAC
TTCATTAAGGAAGTGATTAG

Downstream 100 bases:

>100_bases
ACGTCGACAAAGTTAACGATGGAACGCCGTGTGAGTGTGAAAGCCTCATGCACGGTGTGGAGTGGGGGAAAAGCTGGAGA
TAATATCAAATGCTTACCTA

Product: group II intron

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease [H]

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MADLMIQKLRNNEYFGLQSTFDNLYEESKKGRYFKNIYELIISEENIRLAFRNLKSNIGSKTKGTNGHTIKHLNKIDADK
LIRLTQKRLENYMPHAVRRLFISKPNGKMRPLGIPTIEDRLIQQMFQQVLEPIVEGKFHPQSYGFRPKRGTHDALARCYH
MVNHSHQHFVVDIDIKGFFDNVNHKKLMRQLWTIGIRDKKVLSIIKKMLKAEVTGEGIPVKGTPQGGILSPLLANVVLNE
LDWWVSNQWETKPTRVPYKLKRNKTDALKKTRLKPMYLVRYADDFKIFTNSYDNARKIKIAVEKWLKERLGLEISEEKSK
ITNLRKNGTDFLGIRFRAVQKGNAKTGYIVNSKMDPKAKDKVLGVIRHQLVKLRKSPTPEKVMNFNSNILGLHNYYKIAT
RISQDFNELRHKIHPNIKSLMFRNIFVYTIETNHIIDKFYGDYNCPRFKSNGLLVYPIEAIRHDIRGQRDPNFSVYNKKD
RASIHKEIKHVSVREIEMFRKGIYKAKSVLYENNRLSKYVAQKGCCGITGERLTPHNAICHHIKPTGQGGSDEYHNLIII
NKKYHTLIHNKDPLANEDYKKMLVKLEKKALNKLNKLRTEVGNPKLSL

Sequences:

>Translated_608_residues
MADLMIQKLRNNEYFGLQSTFDNLYEESKKGRYFKNIYELIISEENIRLAFRNLKSNIGSKTKGTNGHTIKHLNKIDADK
LIRLTQKRLENYMPHAVRRLFISKPNGKMRPLGIPTIEDRLIQQMFQQVLEPIVEGKFHPQSYGFRPKRGTHDALARCYH
MVNHSHQHFVVDIDIKGFFDNVNHKKLMRQLWTIGIRDKKVLSIIKKMLKAEVTGEGIPVKGTPQGGILSPLLANVVLNE
LDWWVSNQWETKPTRVPYKLKRNKTDALKKTRLKPMYLVRYADDFKIFTNSYDNARKIKIAVEKWLKERLGLEISEEKSK
ITNLRKNGTDFLGIRFRAVQKGNAKTGYIVNSKMDPKAKDKVLGVIRHQLVKLRKSPTPEKVMNFNSNILGLHNYYKIAT
RISQDFNELRHKIHPNIKSLMFRNIFVYTIETNHIIDKFYGDYNCPRFKSNGLLVYPIEAIRHDIRGQRDPNFSVYNKKD
RASIHKEIKHVSVREIEMFRKGIYKAKSVLYENNRLSKYVAQKGCCGITGERLTPHNAICHHIKPTGQGGSDEYHNLIII
NKKYHTLIHNKDPLANEDYKKMLVKLEKKALNKLNKLRTEVGNPKLSL
>Mature_607_residues
ADLMIQKLRNNEYFGLQSTFDNLYEESKKGRYFKNIYELIISEENIRLAFRNLKSNIGSKTKGTNGHTIKHLNKIDADKL
IRLTQKRLENYMPHAVRRLFISKPNGKMRPLGIPTIEDRLIQQMFQQVLEPIVEGKFHPQSYGFRPKRGTHDALARCYHM
VNHSHQHFVVDIDIKGFFDNVNHKKLMRQLWTIGIRDKKVLSIIKKMLKAEVTGEGIPVKGTPQGGILSPLLANVVLNEL
DWWVSNQWETKPTRVPYKLKRNKTDALKKTRLKPMYLVRYADDFKIFTNSYDNARKIKIAVEKWLKERLGLEISEEKSKI
TNLRKNGTDFLGIRFRAVQKGNAKTGYIVNSKMDPKAKDKVLGVIRHQLVKLRKSPTPEKVMNFNSNILGLHNYYKIATR
ISQDFNELRHKIHPNIKSLMFRNIFVYTIETNHIIDKFYGDYNCPRFKSNGLLVYPIEAIRHDIRGQRDPNFSVYNKKDR
ASIHKEIKHVSVREIEMFRKGIYKAKSVLYENNRLSKYVAQKGCCGITGERLTPHNAICHHIKPTGQGGSDEYHNLIIIN
KKYHTLIHNKDPLANEDYKKMLVKLEKKALNKLNKLRTEVGNPKLSL

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226521, Length=436, Percent_Identity=25.9174311926606, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6226520, Length=428, Percent_Identity=27.5700934579439, Blast_Score=114, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477 [H]

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 70880; Mature: 70748

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLMIQKLRNNEYFGLQSTFDNLYEESKKGRYFKNIYELIISEENIRLAFRNLKSNIGS
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
KTKGTNGHTIKHLNKIDADKLIRLTQKRLENYMPHAVRRLFISKPNGKMRPLGIPTIEDR
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
LIQQMFQQVLEPIVEGKFHPQSYGFRPKRGTHDALARCYHMVNHSHQHFVVDIDIKGFFD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCC
NVNHKKLMRQLWTIGIRDKKVLSIIKKMLKAEVTGEGIPVKGTPQGGILSPLLANVVLNE
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LDWWVSNQWETKPTRVPYKLKRNKTDALKKTRLKPMYLVRYADDFKIFTNSYDNARKIKI
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCCCCHHHHH
AVEKWLKERLGLEISEEKSKITNLRKNGTDFLGIRFRAVQKGNAKTGYIVNSKMDPKAKD
HHHHHHHHHHCCEECHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEECCCCCCHHHH
KVLGVIRHQLVKLRKSPTPEKVMNFNSNILGLHNYYKIATRISQDFNELRHKIHPNIKSL
HHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MFRNIFVYTIETNHIIDKFYGDYNCPRFKSNGLLVYPIEAIRHDIRGQRDPNFSVYNKKD
HHCCEEEEEEECCHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCHH
RASIHKEIKHVSVREIEMFRKGIYKAKSVLYENNRLSKYVAQKGCCGITGERLTPHNAIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
HHIKPTGQGGSDEYHNLIIINKKYHTLIHNKDPLANEDYKKMLVKLEKKALNKLNKLRTE
HCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGNPKLSL
HCCCCCCC
>Mature Secondary Structure 
ADLMIQKLRNNEYFGLQSTFDNLYEESKKGRYFKNIYELIISEENIRLAFRNLKSNIGS
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
KTKGTNGHTIKHLNKIDADKLIRLTQKRLENYMPHAVRRLFISKPNGKMRPLGIPTIEDR
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
LIQQMFQQVLEPIVEGKFHPQSYGFRPKRGTHDALARCYHMVNHSHQHFVVDIDIKGFFD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCC
NVNHKKLMRQLWTIGIRDKKVLSIIKKMLKAEVTGEGIPVKGTPQGGILSPLLANVVLNE
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LDWWVSNQWETKPTRVPYKLKRNKTDALKKTRLKPMYLVRYADDFKIFTNSYDNARKIKI
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCCCCHHHHH
AVEKWLKERLGLEISEEKSKITNLRKNGTDFLGIRFRAVQKGNAKTGYIVNSKMDPKAKD
HHHHHHHHHHCCEECHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEECCCCCCHHHH
KVLGVIRHQLVKLRKSPTPEKVMNFNSNILGLHNYYKIATRISQDFNELRHKIHPNIKSL
HHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MFRNIFVYTIETNHIIDKFYGDYNCPRFKSNGLLVYPIEAIRHDIRGQRDPNFSVYNKKD
HHCCEEEEEEECCHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCHH
RASIHKEIKHVSVREIEMFRKGIYKAKSVLYENNRLSKYVAQKGCCGITGERLTPHNAIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
HHIKPTGQGGSDEYHNLIIINKKYHTLIHNKDPLANEDYKKMLVKLEKKALNKLNKLRTE
HCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGNPKLSL
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786 [H]