Click here to switch to the map view.

The map label for this gene is yxeI [H]

Identifier: 118478988

GI number: 118478988

Start: 3601113

End: 3602108

Strand: Reverse

Name: yxeI [H]

Synonym: BALH_3395

Alternate gene names: 118478988

Gene position: 3602108-3601113 (Counterclockwise)

Preceding gene: 118478989

Following gene: 118478986

Centisome position: 68.52

GC content: 38.15

Gene sequence:

>996_bases
GTGTTCTTTATGTGTACGAGTTTGACATTACAGACAAAAAACGGTCAGCATCTTTTTGCAAGAACGATGGACTTCACATT
AGATATGAATCAAGAAGTAATAATCATTCCTCGACATTACCAGTGGAATAATATAACTGGTGAAATCATTAATACGAAAC
ATGCTACGGTCGGAATGGGTATTAATCATCAAGGAAGGATCATTATGGCGGACGGAGTAAATGAAGCGGGTCTGACATGT
GCGACACTCTATTTTCCAGGATTCGCTACTTATAGTCAAAGCATAGATGACAATAAAACGAATTTGGCTCCATTTGATTT
TGTGACTTGGAGTCTGACACAATTCAACTCTGTCAAAGAGTTAAAGGAATCTGTAGATAGCCTTACCTTTTTGGATATAC
CATTACCGGATTTAGGAGTTACGCCACCACTACATTGGATTTTAGCGGATAAATGGGGAGATTGCATTGTACTGGAGCCG
ACAAATGAAGGATTAAAAATGTATGACAACCCACTAGGAGTGATGACGAATAGTCCGGAGTTTAATTGGCACTTACAAAA
TTTAAGACAATATATAGGCCTTAAATCGCAGCCATTCGCGCCAACAGAGTGGAGTAACTTATTATTAAGTGCTTTTGGTC
AAGGATCGGGCTCAATGGGACTTCCAGGAGATTTCACCCCGCCATCAAGGTTTGTGCGGGCAGCATATGGCAAACAAAAC
ATTCAAGGTATAGATAGCGAAGAAGAGGGAGTAACGGCCCTTTTTCATATTTTATCAAATTGTGAGGTTCCTAAAGGCGG
AGTAATAACAGAAGAAGGGGCATTAGATAATACTATATATACAAGCGTAATGTGTATGGAGTCCGGAACATATTATTATC
ATACCTACGATTGTAGACAAATTATAGCTATTCAGTTATTTCATGAAAATTTAGATACAGATGAGATTAAAGCCTATCCG
TTCCAACGGAAACAAAAAATATTTTATGAGAACTAA

Upstream 100 bases:

>100_bases
TTATACTAAGTGTAGAAAAATCATATGAATCCATAGAAAGAGGTTTTAATTTACAGACTTATCAGAACTGTGTAAAGTGT
AGATAAAATCATAAAACGGG

Downstream 100 bases:

>100_bases
GTAGCCTTGAAACAACCTTTGGTAAATTTTAAAAAATATATATAATAGAGCAATAATGCCTATAAAAAGTAGGGATTGGA
AGGGATATAAATTCAATCCA

Product: penicillin V acylase precursor. cysteine peptidase. MEROPS family C59

Products: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate; glycine

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MFFMCTSLTLQTKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINHQGRIIMADGVNEAGLTC
ATLYFPGFATYSQSIDDNKTNLAPFDFVTWSLTQFNSVKELKESVDSLTFLDIPLPDLGVTPPLHWILADKWGDCIVLEP
TNEGLKMYDNPLGVMTNSPEFNWHLQNLRQYIGLKSQPFAPTEWSNLLLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQN
IQGIDSEEEGVTALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIAIQLFHENLDTDEIKAYP
FQRKQKIFYEN

Sequences:

>Translated_331_residues
MFFMCTSLTLQTKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINHQGRIIMADGVNEAGLTC
ATLYFPGFATYSQSIDDNKTNLAPFDFVTWSLTQFNSVKELKESVDSLTFLDIPLPDLGVTPPLHWILADKWGDCIVLEP
TNEGLKMYDNPLGVMTNSPEFNWHLQNLRQYIGLKSQPFAPTEWSNLLLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQN
IQGIDSEEEGVTALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIAIQLFHENLDTDEIKAYP
FQRKQKIFYEN
>Mature_331_residues
MFFMCTSLTLQTKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINHQGRIIMADGVNEAGLTC
ATLYFPGFATYSQSIDDNKTNLAPFDFVTWSLTQFNSVKELKESVDSLTFLDIPLPDLGVTPPLHWILADKWGDCIVLEP
TNEGLKMYDNPLGVMTNSPEFNWHLQNLRQYIGLKSQPFAPTEWSNLLLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQN
IQGIDSEEEGVTALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIAIQLFHENLDTDEIKAYP
FQRKQKIFYEN

Specific function: Unknown

COG id: COG3049

COG function: function code M; Penicillin V acylase and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C59 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003199 [H]

Pfam domain/function: PF02275 CBAH [H]

EC number: 3.5.1.24

Molecular weight: Translated: 37375; Mature: 37375

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFMCTSLTLQTKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMG
CEEEEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEECEEECCCCCEEEEECCCEEEECC
INHQGRIIMADGVNEAGLTCATLYFPGFATYSQSIDDNKTNLAPFDFVTWSLTQFNSVKE
CCCCCCEEEECCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHH
LKESVDSLTFLDIPLPDLGVTPPLHWILADKWGDCIVLEPTNEGLKMYDNPLGVMTNSPE
HHHHHHCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEECCCCCEEECCCC
FNWHLQNLRQYIGLKSQPFAPTEWSNLLLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQN
CCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCC
IQGIDSEEEGVTALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQ
CCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCHHEEEEEEEECCEEEEEEECHHH
IIAIQLFHENLDTDEIKAYPFQRKQKIFYEN
EEEEEEHHCCCCCCCEEECCCCHHCCCCCCC
>Mature Secondary Structure
MFFMCTSLTLQTKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMG
CEEEEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEECEEECCCCCEEEEECCCEEEECC
INHQGRIIMADGVNEAGLTCATLYFPGFATYSQSIDDNKTNLAPFDFVTWSLTQFNSVKE
CCCCCCEEEECCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHH
LKESVDSLTFLDIPLPDLGVTPPLHWILADKWGDCIVLEPTNEGLKMYDNPLGVMTNSPE
HHHHHHCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEECCCCCEEECCCC
FNWHLQNLRQYIGLKSQPFAPTEWSNLLLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQN
CCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCC
IQGIDSEEEGVTALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQ
CCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCHHEEEEEEEECCEEEEEEECHHH
IIAIQLFHENLDTDEIKAYPFQRKQKIFYEN
EEEEEEHHCCCCCCCEEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine; H2O

Specific reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]