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The map label for this gene is murG

Identifier: 118478972

GI number: 118478972

Start: 3579343

End: 3580407

Strand: Reverse

Name: murG

Synonym: BALH_3379

Alternate gene names: 118478972

Gene position: 3580407-3579343 (Counterclockwise)

Preceding gene: 118478973

Following gene: 118478970

Centisome position: 68.11

GC content: 35.02

Gene sequence:

>1065_bases
ATGAATAAAAAGATTCTCTTTACTGGGGGCGGTACAGCCGGACATGTAATGATTAATATGGTATTGATTCCCAAATTCAT
GGGAAAAGGATGGGGAGTTGAGTATATTGGATCTCAAAATGGAATTGAAAAACTATTAGTTCAAAATGTTAAATACAATA
GTATTTCAACGGGGAAGCTTAGGAGATATTGGGATTGGGAGAACTTTAAAGATCCTTTTAAAATAATAAAAGGTTGCATA
CAAAGTTATAAATTAATGAAACGGATAAAACCAGATGTTATTTTTTCGGCAGGAGGATTTGTTTCCGTTCCTGTAGTAAT
AGGAGCGTGGATGAATAAAGTACCCGTAATAATACGTGAACCGGACAGTACGTTAGGATTAGCAAATAAAATAGCATTAC
CATTTACTACAAAACTATGCACAACATTTCCTCAGACAGGAGAAAATGTAAGTAATGAGAAAAAGGTTTATGTAGGACCA
ATTGTAAGAGAAGAAATTGAGAGGGGCAACGTATTGCGGGGAAGAAGCTATTGTAAATTTCAGCAAGATAAACCAGTATT
GTTAATTATGGGTGGGAGTCAAGGTGCTCAATGGATAAATGATATGGTAAGGGGAAGTTTGGAAACATTACTATTAAATT
TTAATATTGTTCATATGTGCGGTAAAGGGAAGGTCGATTCATCTATTGGCATGGAGGGCTATATACAATTTGAATATATA
GGGGAAGAGTTGCCGCATATACTAAATATGGCGAGTGTTGTAGTTTCGAGAGCGGGTTCTACTGCTATCTTCGAATTGCT
ATTCTTGAAGAAACCGATGTTGCTTATCCCGTTAACTAACAGTTCCAGTAGGGGAGATCAAGTTTTAAATGCTGAATATT
TTTCTCGGCAAGGATATGCGGAAGTTATACTTCAAGACAGAGTAAGTACGAATACATTTATACATGCAGTAAATAAGTTG
AATACAAATAAGGAGAGATACATTCAAAACATGAATGGCTATACGAAAACAAATGATGAGGGGATTCATCAATTAATAGA
TATAATAAATGAAGTGGTGAAGTAA

Upstream 100 bases:

>100_bases
AGGATTTGAATTAAATGTTTATATAAATAATAGTAAGTTTACTTACATTTAATAGATTAGTATAAAACAAGATTTTTAAT
GATAAAGGTGGATATAAATT

Downstream 100 bases:

>100_bases
TAGAAATTTAAATAGAAAAAACAAAAGGAAAGAAGGTATCTTCTTTCCTTTTTACTATAGTTGTTCAAATTCATTATTAC
TTATCCCGATTAACTATGTA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 1

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNKKILFTGGGTAGHVMINMVLIPKFMGKGWGVEYIGSQNGIEKLLVQNVKYNSISTGKLRRYWDWENFKDPFKIIKGCI
QSYKLMKRIKPDVIFSAGGFVSVPVVIGAWMNKVPVIIREPDSTLGLANKIALPFTTKLCTTFPQTGENVSNEKKVYVGP
IVREEIERGNVLRGRSYCKFQQDKPVLLIMGGSQGAQWINDMVRGSLETLLLNFNIVHMCGKGKVDSSIGMEGYIQFEYI
GEELPHILNMASVVVSRAGSTAIFELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYAEVILQDRVSTNTFIHAVNKL
NTNKERYIQNMNGYTKTNDEGIHQLIDIINEVVK

Sequences:

>Translated_354_residues
MNKKILFTGGGTAGHVMINMVLIPKFMGKGWGVEYIGSQNGIEKLLVQNVKYNSISTGKLRRYWDWENFKDPFKIIKGCI
QSYKLMKRIKPDVIFSAGGFVSVPVVIGAWMNKVPVIIREPDSTLGLANKIALPFTTKLCTTFPQTGENVSNEKKVYVGP
IVREEIERGNVLRGRSYCKFQQDKPVLLIMGGSQGAQWINDMVRGSLETLLLNFNIVHMCGKGKVDSSIGMEGYIQFEYI
GEELPHILNMASVVVSRAGSTAIFELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYAEVILQDRVSTNTFIHAVNKL
NTNKERYIQNMNGYTKTNDEGIHQLIDIINEVVK
>Mature_354_residues
MNKKILFTGGGTAGHVMINMVLIPKFMGKGWGVEYIGSQNGIEKLLVQNVKYNSISTGKLRRYWDWENFKDPFKIIKGCI
QSYKLMKRIKPDVIFSAGGFVSVPVVIGAWMNKVPVIIREPDSTLGLANKIALPFTTKLCTTFPQTGENVSNEKKVYVGP
IVREEIERGNVLRGRSYCKFQQDKPVLLIMGGSQGAQWINDMVRGSLETLLLNFNIVHMCGKGKVDSSIGMEGYIQFEYI
GEELPHILNMASVVVSRAGSTAIFELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYAEVILQDRVSTNTFIHAVNKL
NTNKERYIQNMNGYTKTNDEGIHQLIDIINEVVK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=320, Percent_Identity=28.125, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG1_BACAH (A0RHC3)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_896123.1
- ProteinModelPortal:   A0RHC3
- SMR:   A0RHC3
- STRING:   A0RHC3
- EnsemblBacteria:   EBBACT00000067146
- GeneID:   4544857
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_3379
- NMPDR:   fig|412694.5.peg.3247
- eggNOG:   COG0707
- GeneTree:   EBGT00050000001194
- HOGENOM:   HBG617076
- OMA:   AKWINDM
- ProtClustDB:   PRK12446
- BioCyc:   BTHU412694:BALH_3379-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39725; Mature: 39725

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKILFTGGGTAGHVMINMVLIPKFMGKGWGVEYIGSQNGIEKLLVQNVKYNSISTGKL
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCC
RRYWDWENFKDPFKIIKGCIQSYKLMKRIKPDVIFSAGGFVSVPVVIGAWMNKVPVIIRE
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEHHHHHHHHHCCCCEEEEC
PDSTLGLANKIALPFTTKLCTTFPQTGENVSNEKKVYVGPIVREEIERGNVLRGRSYCKF
CCCHHCCHHEEECCHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHCCCEECCCCCCCC
QQDKPVLLIMGGSQGAQWINDMVRGSLETLLLNFNIVHMCGKGKVDSSIGMEGYIQFEYI
CCCCCEEEEEECCCCHHHHHHHHHCCHHHHHEECEEEEEECCCCCCCCCCCCEEEEEEEH
GEELPHILNMASVVVSRAGSTAIFELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCCHH
EVILQDRVSTNTFIHAVNKLNTNKERYIQNMNGYTKTNDEGIHQLIDIINEVVK
HHHHHHCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKKILFTGGGTAGHVMINMVLIPKFMGKGWGVEYIGSQNGIEKLLVQNVKYNSISTGKL
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCC
RRYWDWENFKDPFKIIKGCIQSYKLMKRIKPDVIFSAGGFVSVPVVIGAWMNKVPVIIRE
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEHHHHHHHHHCCCCEEEEC
PDSTLGLANKIALPFTTKLCTTFPQTGENVSNEKKVYVGPIVREEIERGNVLRGRSYCKF
CCCHHCCHHEEECCHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHCCCEECCCCCCCC
QQDKPVLLIMGGSQGAQWINDMVRGSLETLLLNFNIVHMCGKGKVDSSIGMEGYIQFEYI
CCCCCEEEEEECCCCHHHHHHHHHCCHHHHHEECEEEEEECCCCCCCCCCCCEEEEEEEH
GEELPHILNMASVVVSRAGSTAIFELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCCHH
EVILQDRVSTNTFIHAVNKLNTNKERYIQNMNGYTKTNDEGIHQLIDIINEVVK
HHHHHHCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA