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The map label for this gene is ntdR [H]

Identifier: 118478550

GI number: 118478550

Start: 3104452

End: 3105441

Strand: Direct

Name: ntdR [H]

Synonym: BALH_2926

Alternate gene names: 118478550

Gene position: 3104452-3105441 (Clockwise)

Preceding gene: 118478535

Following gene: 118478551

Centisome position: 59.05

GC content: 28.99

Gene sequence:

>990_bases
ATGGTAACAATTAACGAAATAGCTAAATTATGTAATGTATCAAATGCTACGGTTTCAAGAGTTCTAAATAATCATCCTTA
TGTAAATTCAGAAAAACGTGAGAAAATAATAAAAGTAATGCAAGAATTCAACTATACTCCTAGTGCTATTGCTAGAAATC
TTAGGATAAATAAGACACAAACCATTGCTCTATCAATTCCAAATATAGATCATCCCTTTTTCGGGAAATTAGCTAGAGAA
ATTTCTAAAGAATTATTAAAACACAATTACAAATTGCTAATTTATCAGACTTTTTATGAGAAAAAAATAGAGCTTGAATT
ACTTTCATTACTAAAGAATAAAGCTGTAGATGGTGTAATTCTCGCATCTCTAGAAAATAGTTGGGAAAATATAGAGCATT
ATTTAGCATATGGGCCCATAATACTTTGTAATGAGTATGAGGAAAATGCACCTATTCCGATAATTTGTTACGATGAATTT
GAAGCTGGATACAAAGCTGTTAAACATTTAATAAGCAAAGGTCATAAAAAAATTGGCTTTTGTTTTGATTCTCTTAATAG
TCAAGCACAATTAAAACGCCAACAAGGTTATCTGCATGCCTTAAAAGAAAAACAATTACCATTCAATAAAAATTGGCTAT
TTGGAGATGCAATTACTATTAATGATGGATTTAAAATTTTTGAGAAGCTAGATAAATTAAAAGATAAACCTACTGCATTA
TTTACTGGAAATGATCAAGTTGCTGCTGGAGTCATTAAAGGAGCTACTATTAAAGGGTATTCTATTCCAACTGACTTAGC
TGTTTGTGGTTATGATAATCAATTAATTTGTACAGTTACAACCCCAACAATTAGTACTATTGATATTCCAATTGTTGAAC
TGAGTAAACGTACCGTTAACGAGATACTACTATATATAAATACAGATGAATCTATTAAACGAAAAATTATTGAATATCCT
ACTAACTTAATTATTCGTGAATCTACATAA

Upstream 100 bases:

>100_bases
ACGTTAAATCACCTCTAAGAAATTATTTTGAAAATCATGAGTAGACTATATTTTATGTTATCGATTACATGTCAACATAT
TTTTTACGGAGGGTTTTTCT

Downstream 100 bases:

>100_bases
TTAAAATAAAAGTTTCTGCTTAAACTTATATAATAAATATAAATAAAAAGAGGACGTAAATAATAATGTGTCCTCTTTTT
ATCATTTTAGGCATTAAATT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MVTINEIAKLCNVSNATVSRVLNNHPYVNSEKREKIIKVMQEFNYTPSAIARNLRINKTQTIALSIPNIDHPFFGKLARE
ISKELLKHNYKLLIYQTFYEKKIELELLSLLKNKAVDGVILASLENSWENIEHYLAYGPIILCNEYEENAPIPIICYDEF
EAGYKAVKHLISKGHKKIGFCFDSLNSQAQLKRQQGYLHALKEKQLPFNKNWLFGDAITINDGFKIFEKLDKLKDKPTAL
FTGNDQVAAGVIKGATIKGYSIPTDLAVCGYDNQLICTVTTPTISTIDIPIVELSKRTVNEILLYINTDESIKRKIIEYP
TNLIIREST

Sequences:

>Translated_329_residues
MVTINEIAKLCNVSNATVSRVLNNHPYVNSEKREKIIKVMQEFNYTPSAIARNLRINKTQTIALSIPNIDHPFFGKLARE
ISKELLKHNYKLLIYQTFYEKKIELELLSLLKNKAVDGVILASLENSWENIEHYLAYGPIILCNEYEENAPIPIICYDEF
EAGYKAVKHLISKGHKKIGFCFDSLNSQAQLKRQQGYLHALKEKQLPFNKNWLFGDAITINDGFKIFEKLDKLKDKPTAL
FTGNDQVAAGVIKGATIKGYSIPTDLAVCGYDNQLICTVTTPTISTIDIPIVELSKRTVNEILLYINTDESIKRKIIEYP
TNLIIREST
>Mature_329_residues
MVTINEIAKLCNVSNATVSRVLNNHPYVNSEKREKIIKVMQEFNYTPSAIARNLRINKTQTIALSIPNIDHPFFGKLARE
ISKELLKHNYKLLIYQTFYEKKIELELLSLLKNKAVDGVILASLENSWENIEHYLAYGPIILCNEYEENAPIPIICYDEF
EAGYKAVKHLISKGHKKIGFCFDSLNSQAQLKRQQGYLHALKEKQLPFNKNWLFGDAITINDGFKIFEKLDKLKDKPTAL
FTGNDQVAAGVIKGATIKGYSIPTDLAVCGYDNQLICTVTTPTISTIDIPIVELSKRTVNEILLYINTDESIKRKIIEYP
TNLIIREST

Specific function: Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=351, Percent_Identity=27.0655270655271, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790369, Length=299, Percent_Identity=28.7625418060201, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=28.7009063444109, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788474, Length=297, Percent_Identity=27.6094276094276, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789068, Length=312, Percent_Identity=27.2435897435897, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789202, Length=300, Percent_Identity=27.3333333333333, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787580, Length=306, Percent_Identity=25.8169934640523, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI48994940, Length=317, Percent_Identity=21.7665615141956, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786268, Length=302, Percent_Identity=24.1721854304636, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787906, Length=338, Percent_Identity=23.3727810650888, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790715, Length=313, Percent_Identity=22.0447284345048, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790689, Length=318, Percent_Identity=23.8993710691824, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789456, Length=355, Percent_Identity=22.2535211267606, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37415; Mature: 37415

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTINEIAKLCNVSNATVSRVLNNHPYVNSEKREKIIKVMQEFNYTPSAIARNLRINKTQ
CEEHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEE
TIALSIPNIDHPFFGKLAREISKELLKHNYKLLIYQTFYEKKIELELLSLLKNKAVDGVI
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCEE
LASLENSWENIEHYLAYGPIILCNEYEENAPIPIICYDEFEAGYKAVKHLISKGHKKIGF
EEEHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEH
CFDSLNSQAQLKRQQGYLHALKEKQLPFNKNWLFGDAITINDGFKIFEKLDKLKDKPTAL
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEECCCHHHHHHHHHHCCCCCEE
FTGNDQVAAGVIKGATIKGYSIPTDLAVCGYDNQLICTVTTPTISTIDIPIVELSKRTVN
EECCCCEEHHEEECCEEECCCCCCCEEEECCCCEEEEEEECCCCEEEECCHHHHHHHCCE
EILLYINTDESIKRKIIEYPTNLIIREST
EEEEEEECCHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MVTINEIAKLCNVSNATVSRVLNNHPYVNSEKREKIIKVMQEFNYTPSAIARNLRINKTQ
CEEHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEE
TIALSIPNIDHPFFGKLAREISKELLKHNYKLLIYQTFYEKKIELELLSLLKNKAVDGVI
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCEE
LASLENSWENIEHYLAYGPIILCNEYEENAPIPIICYDEFEAGYKAVKHLISKGHKKIGF
EEEHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEH
CFDSLNSQAQLKRQQGYLHALKEKQLPFNKNWLFGDAITINDGFKIFEKLDKLKDKPTAL
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEECCCHHHHHHHHHHCCCCCEE
FTGNDQVAAGVIKGATIKGYSIPTDLAVCGYDNQLICTVTTPTISTIDIPIVELSKRTVN
EECCCCEEHHEEECCEEECCCCCCCEEEECCCCEEEEEEECCCCEEEECCHHHHHHHCCE
EILLYINTDESIKRKIIEYPTNLIIREST
EEEEEEECCHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]