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The map label for this gene is npr [H]

Identifier: 118478539

GI number: 118478539

Start: 3089583

End: 3091313

Strand: Reverse

Name: npr [H]

Synonym: BALH_2915

Alternate gene names: 118478539

Gene position: 3091313-3089583 (Counterclockwise)

Preceding gene: 118478540

Following gene: 118478538

Centisome position: 58.8

GC content: 34.2

Gene sequence:

>1731_bases
TTGTATATTAAATTTTGCAATTATTTCTTTTATATTACTCATATTGAAGGGGGAAAACGAATGAAAAAAACGGTTATTAC
ATTGCTTGCTGCAGGAACAATGTTAGGTGCTCCTTTTTCAACTGCGTTTGCAGAAGAACAAGCCTATCAACAAGAAGCAA
TGGATAAAATGGAGGTACTACAAAAAAATTGGAATGAGGAACAGGGAAGTCCATCATTTCTTTCAGGTGATTTATCTGAT
AAAAAGGTAGAGACTCAAAAAGCGGTAAAAGAGTTTCTTGAAGAAAATAAAGAATTATTTAAAATAAATCCACAAAAAGA
TTTAACACTTAAAGAAGTGAAATCAGATGATTTAGGTATGAAACATTATGTTTATACACGATCTATAAATAAAATACCTG
TTGACGGTGCACAATTTATTGTACATACAGATAAAGAGGGTAAAGTAACTACAGTCAATGGAGATGTCCATCCAGCTGCA
GAGGAGAGTTTAAAGGGTAATACAAAAGCAAAAATTACAAAGGAAACAGCACTTTCAAATGCTTGGAAACATATTAAACT
TACAAAAAGTGATACGCTAGTAAAAATGGACGGAAATGCATTAGATCAGATAAAAGAAAACCTAGAGTCTACTAATGAAA
CAGCAGATTTAGTTGTATACGAAAAAGATGGAACATACTATTTAACGTTTAAAGTGAAACTACAATTTATTAAACCCTAT
GGTGCTAACTGGCACATCTATGTTAATGCGGAAGATGGGACAATTGTAGATTCATATAATGCAGTTACAGATGCAGATAG
TGCTCATAAAGGCTACGGATATGGGGTATTAGGTGATAAAAAAGAATTGAATACAACTTTTAGTAGTGTAAAGGGAAAAT
ACTACTTAAAAGACACAACAAAACCTATGAATGGCGGCTACATTGAAACATTTACAGTAAATCATAGTGATGAAGATTAT
CCAATAAATTATCGTTTGTTTGATGAGGATAATGCTTGGATAAATAAAGATCAGAGGCCAGCAGTTGATGCCCATTACTA
TGCAGGAAAAGTCTATGATTATTATAAAAATGTCCATAATCGTAACAGTATTGATGGGAAAGGTAAAACAATTCGCTCTG
CTGTGAATTATGGGGTTAACGTAAATAACGCATTTTGGAATGGTCAGCAAATGATATATGGAGATGGAGATGGTCGCAGA
TTTATTCCGCTTTCTGGTTCTCTTGATGTTGTGGCACATGAATTAACTCATGCTGTTACAGAGTATTCTGCTGATCTTCG
TTACGTAAATCAATCAGGTGCATTAAATGAATCTTTCTCTGATGTGTTTGGCTATTTTGTTGATCCTACCAATTGGGATG
TAGGGGATGCTGTATTTACACCTGGTGTTTCTGGAGACGCATTGCGAAGCTTATCTAATCCTGAGAAATATGGACAACCT
GCTCATATGAGAAACTACCAATATCTTCCGGAAACTGAAGAGGGAGATAATGGTGGAGTGCATATAAATAGTGGTATTCC
GAATAAGGCTGCATATTTGACAATTAATTCTATTGGTAAAGAAAAGGCAGAAAAAATCTATTATCGTGCGTTAACAATAT
ATTTGACTCCAACTAGCGATTTTAAACAAGCTCGTACTGCTTTATTACAATCTGCGGCTGATTATGATGGTTATGATAGT
GTAACGTATAAAGCCATAGAAAATGCTTGGAATCAGGTCGGTGTAAAATAA

Upstream 100 bases:

>100_bases
TAGGCATGTGAAGGTACCTCTATAAGGAATTTATATCTCAATAATTTTATAAATAGATAATATGCAATTGTTCATATTTA
TACAAAAAATTCGAAAATAA

Downstream 100 bases:

>100_bases
TTTAGTTACTATAGGCTAGGAAGTATAGCTATTAAAACCGAAAAAGAACACACTTGTATAACAATAAAGTGTGTTCTTTT
TCGGTGTTTTTTGTATTGTT

Product: neutral protease

Products: NA

Alternate protein names: MCP 76; Neutral protease [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MYIKFCNYFFYITHIEGGKRMKKTVITLLAAGTMLGAPFSTAFAEEQAYQQEAMDKMEVLQKNWNEEQGSPSFLSGDLSD
KKVETQKAVKEFLEENKELFKINPQKDLTLKEVKSDDLGMKHYVYTRSINKIPVDGAQFIVHTDKEGKVTTVNGDVHPAA
EESLKGNTKAKITKETALSNAWKHIKLTKSDTLVKMDGNALDQIKENLESTNETADLVVYEKDGTYYLTFKVKLQFIKPY
GANWHIYVNAEDGTIVDSYNAVTDADSAHKGYGYGVLGDKKELNTTFSSVKGKYYLKDTTKPMNGGYIETFTVNHSDEDY
PINYRLFDEDNAWINKDQRPAVDAHYYAGKVYDYYKNVHNRNSIDGKGKTIRSAVNYGVNVNNAFWNGQQMIYGDGDGRR
FIPLSGSLDVVAHELTHAVTEYSADLRYVNQSGALNESFSDVFGYFVDPTNWDVGDAVFTPGVSGDALRSLSNPEKYGQP
AHMRNYQYLPETEEGDNGGVHINSGIPNKAAYLTINSIGKEKAEKIYYRALTIYLTPTSDFKQARTALLQSAADYDGYDS
VTYKAIENAWNQVGVK

Sequences:

>Translated_576_residues
MYIKFCNYFFYITHIEGGKRMKKTVITLLAAGTMLGAPFSTAFAEEQAYQQEAMDKMEVLQKNWNEEQGSPSFLSGDLSD
KKVETQKAVKEFLEENKELFKINPQKDLTLKEVKSDDLGMKHYVYTRSINKIPVDGAQFIVHTDKEGKVTTVNGDVHPAA
EESLKGNTKAKITKETALSNAWKHIKLTKSDTLVKMDGNALDQIKENLESTNETADLVVYEKDGTYYLTFKVKLQFIKPY
GANWHIYVNAEDGTIVDSYNAVTDADSAHKGYGYGVLGDKKELNTTFSSVKGKYYLKDTTKPMNGGYIETFTVNHSDEDY
PINYRLFDEDNAWINKDQRPAVDAHYYAGKVYDYYKNVHNRNSIDGKGKTIRSAVNYGVNVNNAFWNGQQMIYGDGDGRR
FIPLSGSLDVVAHELTHAVTEYSADLRYVNQSGALNESFSDVFGYFVDPTNWDVGDAVFTPGVSGDALRSLSNPEKYGQP
AHMRNYQYLPETEEGDNGGVHINSGIPNKAAYLTINSIGKEKAEKIYYRALTIYLTPTSDFKQARTALLQSAADYDGYDS
VTYKAIENAWNQVGVK
>Mature_576_residues
MYIKFCNYFFYITHIEGGKRMKKTVITLLAAGTMLGAPFSTAFAEEQAYQQEAMDKMEVLQKNWNEEQGSPSFLSGDLSD
KKVETQKAVKEFLEENKELFKINPQKDLTLKEVKSDDLGMKHYVYTRSINKIPVDGAQFIVHTDKEGKVTTVNGDVHPAA
EESLKGNTKAKITKETALSNAWKHIKLTKSDTLVKMDGNALDQIKENLESTNETADLVVYEKDGTYYLTFKVKLQFIKPY
GANWHIYVNAEDGTIVDSYNAVTDADSAHKGYGYGVLGDKKELNTTFSSVKGKYYLKDTTKPMNGGYIETFTVNHSDEDY
PINYRLFDEDNAWINKDQRPAVDAHYYAGKVYDYYKNVHNRNSIDGKGKTIRSAVNYGVNVNNAFWNGQQMIYGDGDGRR
FIPLSGSLDVVAHELTHAVTEYSADLRYVNQSGALNESFSDVFGYFVDPTNWDVGDAVFTPGVSGDALRSLSNPEKYGQP
AHMRNYQYLPETEEGDNGGVHINSGIPNKAAYLTINSIGKEKAEKIYYRALTIYLTPTSDFKQARTALLQSAADYDGYDS
VTYKAIENAWNQVGVK

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.28 [H]

Molecular weight: Translated: 64728; Mature: 64728

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIKFCNYFFYITHIEGGKRMKKTVITLLAAGTMLGAPFSTAFAEEQAYQQEAMDKMEVL
CEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QKNWNEEQGSPSFLSGDLSDKKVETQKAVKEFLEENKELFKINPQKDLTLKEVKSDDLGM
HHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCC
KHYVYTRSINKIPVDGAQFIVHTDKEGKVTTVNGDVHPAAEESLKGNTKAKITKETALSN
EEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHCCCCCCEEEEHHHHHHC
AWKHIKLTKSDTLVKMDGNALDQIKENLESTNETADLVVYEKDGTYYLTFKVKLQFIKPY
CHHEEEEECCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEEEEEECCC
GANWHIYVNAEDGTIVDSYNAVTDADSAHKGYGYGVLGDKKELNTTFSSVKGKYYLKDTT
CCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCEEEEECCC
KPMNGGYIETFTVNHSDEDYPINYRLFDEDNAWINKDQRPAVDAHYYAGKVYDYYKNVHN
CCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEECCCCCCCCCCHHHHCHHHHHHHHHCC
RNSIDGKGKTIRSAVNYGVNVNNAFWNGQQMIYGDGDGRRFIPLSGSLDVVAHELTHAVT
CCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
EYSADLRYVNQSGALNESFSDVFGYFVDPTNWDVGDAVFTPGVSGDALRSLSNPEKYGQP
HHCCCCEEECCCCCCCCCHHHHHHEEECCCCCCCCCCEECCCCCHHHHHHCCCHHHHCCC
AHMRNYQYLPETEEGDNGGVHINSGIPNKAAYLTINSIGKEKAEKIYYRALTIYLTPTSD
CHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEHHCHHHHHHEEEEEEEEEEECCHH
FKQARTALLQSAADYDGYDSVTYKAIENAWNQVGVK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYIKFCNYFFYITHIEGGKRMKKTVITLLAAGTMLGAPFSTAFAEEQAYQQEAMDKMEVL
CEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QKNWNEEQGSPSFLSGDLSDKKVETQKAVKEFLEENKELFKINPQKDLTLKEVKSDDLGM
HHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCC
KHYVYTRSINKIPVDGAQFIVHTDKEGKVTTVNGDVHPAAEESLKGNTKAKITKETALSN
EEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHCCCCCCEEEEHHHHHHC
AWKHIKLTKSDTLVKMDGNALDQIKENLESTNETADLVVYEKDGTYYLTFKVKLQFIKPY
CHHEEEEECCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEEEEEECCC
GANWHIYVNAEDGTIVDSYNAVTDADSAHKGYGYGVLGDKKELNTTFSSVKGKYYLKDTT
CCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCEEEEECCC
KPMNGGYIETFTVNHSDEDYPINYRLFDEDNAWINKDQRPAVDAHYYAGKVYDYYKNVHN
CCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEECCCCCCCCCCHHHHCHHHHHHHHHCC
RNSIDGKGKTIRSAVNYGVNVNNAFWNGQQMIYGDGDGRRFIPLSGSLDVVAHELTHAVT
CCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
EYSADLRYVNQSGALNESFSDVFGYFVDPTNWDVGDAVFTPGVSGDALRSLSNPEKYGQP
HHCCCCEEECCCCCCCCCHHHHHHEEECCCCCCCCCCEECCCCCHHHHHHCCCHHHHCCC
AHMRNYQYLPETEEGDNGGVHINSGIPNKAAYLTINSIGKEKAEKIYYRALTIYLTPTSD
CHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEHHCHHHHHHEEEEEEEEEEECCHH
FKQARTALLQSAADYDGYDSVTYKAIENAWNQVGVK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA