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The map label for this gene is flp [H]

Identifier: 118478507

GI number: 118478507

Start: 3055394

End: 3056935

Strand: Reverse

Name: flp [H]

Synonym: BALH_2880

Alternate gene names: 118478507

Gene position: 3056935-3055394 (Counterclockwise)

Preceding gene: 118478508

Following gene: 118478506

Centisome position: 58.15

GC content: 35.34

Gene sequence:

>1542_bases
ATGAAGAATAGACAAAAAGCATCGATAATATGCAAAAGTATTTTATGTTTTATTATTTGTATATTTATTACGAGTGAAGC
ATGGTTTACAAATGTGGTGAGGGCAGAATCGGGCATGCTGACTGGTAGGAGTATAGAGGATTTCAAAAAAAAGCTGGATG
AACAGGTACCAAAATGGCAGGAGAATTATGAGGTACCAGGGGTTGCAATCGGGATTGTACATGAGGGGCGTATTGCTTAT
ACACTTAACTACGGTTATGTAGATAAAAAGACAAAAAAAGCGGTGAGTGATGATACTTTGTTTCAGGCTGGTTCCATATC
TAAAAGTCTTACAGCGTGGGGAATTTTGCACCTTGTAGATGAAGGGCGTTTATTACTAGATGATCCCGTTGGAAAATATC
TGACCAAATGGAAATTACCTAATTCAGAGTTTAATAATAATGAAGTCACGATAAGAAGATTGTTAAGTCATACAGCAGGG
CTGTCTGCACATAAAGGATATCTCGGGGTTGCACCAGGGAAACATCTTGATTCTATCGAGGAGTCTCTGTCTGGAAAAGG
ATGGCTTAATGAACCAGTGGAAGTTACCAAAAAACCAGGTTCAGAAACAATTTACTCTGGTGGCGGATATACAATTTTAC
AACTTGTAATGGAAGAGGTTACCGGAATATCTTTTGATCGTTATATGGAAGAACAAATTATGAAACCGTTAGGAATGAAA
TCTAGTTCATTTTTACAACGTCCTGAAAACCATAACCTTTCAAAAGCTTATGGATATTTTGGAGAGGAGTTCCCTAGTTA
CCAATTTACCGAACAGGCTGCTGCAGGTCTTAAGACAAATGTTATCGATATGATGACATTGATACTTGCAAGCATGGATA
CAAATAATAAAGGGAATGGTGTCATCAAAAGTGAACGTGTTGAGGAAATGCAAAAGCCAGTATTAGGGGAGAACGGTTTA
GGTATATTTGAAAAAAAACTATCTAATCAATGGAAATTACTTTATCATTCTGGTGACAATCGAGGCTGGCATTCTTTTTA
TGGTTTTATTCCTAATACAAAGGATGGATGGGTAATCCTTACAAATGGTGAAGGTGGTATAGACTTACGACAGGATATTT
ACCACGCATGGATTGAATATGAAACGGGAGAATTACCTGAAAGTTACTTTTCTCTAGCAGAGCAGAGAAAAACTAACTTC
ATTACATCAATTGTTATTGGCGCCACACTTAGTATATATTTGCTACTGTTTGTGATTAGATTGTACAAAGGTAGAAGAGC
GTTCATTTTTAAGCAAGAGAAGAAATCTTACATCGGATTAGTAGTTAGGACATTTTTACTTATTATTACAGCTGTTCTCG
TTTTTTGTGCTGCTTATTTGTGGAGAGTTTTTAGTTTGAATTCCGGTAATACAATAAATTTCATTCTAATAATGGCATGG
ATTATAACGCTATTAATTAGTGGATTTTTCCCGAAAATTAAAAGTAATAAAAAACAACGTATGAAACGAAAAAAATTAAC
ATCAAAATTTACATGTATGTAA

Upstream 100 bases:

>100_bases
CAATTTTGTAAGGTTAAGTAATAAAAATCGATAGAACGGGATATTGGAATGGGATACTCTGATTGATAGGTAGAATATTC
TGAAAAAAGAGGTAGAACAA

Downstream 100 bases:

>100_bases
TGTTAAAGGCTAGAAAGCTAGATTGGCGTGAATCACTAATTGTGGAGTGCAAAAAACAACAAAATCTTTTAAAAAACACT
TAATTTTTTACTCCATCTAT

Product: beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKNRQKASIICKSILCFIICIFITSEAWFTNVVRAESGMLTGRSIEDFKKKLDEQVPKWQENYEVPGVAIGIVHEGRIAY
TLNYGYVDKKTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLLLDDPVGKYLTKWKLPNSEFNNNEVTIRRLLSHTAG
LSAHKGYLGVAPGKHLDSIEESLSGKGWLNEPVEVTKKPGSETIYSGGGYTILQLVMEEVTGISFDRYMEEQIMKPLGMK
SSSFLQRPENHNLSKAYGYFGEEFPSYQFTEQAAAGLKTNVIDMMTLILASMDTNNKGNGVIKSERVEEMQKPVLGENGL
GIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGWVILTNGEGGIDLRQDIYHAWIEYETGELPESYFSLAEQRKTNF
ITSIVIGATLSIYLLLFVIRLYKGRRAFIFKQEKKSYIGLVVRTFLLIITAVLVFCAAYLWRVFSLNSGNTINFILIMAW
IITLLISGFFPKIKSNKKQRMKRKKLTSKFTCM

Sequences:

>Translated_513_residues
MKNRQKASIICKSILCFIICIFITSEAWFTNVVRAESGMLTGRSIEDFKKKLDEQVPKWQENYEVPGVAIGIVHEGRIAY
TLNYGYVDKKTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLLLDDPVGKYLTKWKLPNSEFNNNEVTIRRLLSHTAG
LSAHKGYLGVAPGKHLDSIEESLSGKGWLNEPVEVTKKPGSETIYSGGGYTILQLVMEEVTGISFDRYMEEQIMKPLGMK
SSSFLQRPENHNLSKAYGYFGEEFPSYQFTEQAAAGLKTNVIDMMTLILASMDTNNKGNGVIKSERVEEMQKPVLGENGL
GIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGWVILTNGEGGIDLRQDIYHAWIEYETGELPESYFSLAEQRKTNF
ITSIVIGATLSIYLLLFVIRLYKGRRAFIFKQEKKSYIGLVVRTFLLIITAVLVFCAAYLWRVFSLNSGNTINFILIMAW
IITLLISGFFPKIKSNKKQRMKRKKLTSKFTCM
>Mature_513_residues
MKNRQKASIICKSILCFIICIFITSEAWFTNVVRAESGMLTGRSIEDFKKKLDEQVPKWQENYEVPGVAIGIVHEGRIAY
TLNYGYVDKKTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLLLDDPVGKYLTKWKLPNSEFNNNEVTIRRLLSHTAG
LSAHKGYLGVAPGKHLDSIEESLSGKGWLNEPVEVTKKPGSETIYSGGGYTILQLVMEEVTGISFDRYMEEQIMKPLGMK
SSSFLQRPENHNLSKAYGYFGEEFPSYQFTEQAAAGLKTNVIDMMTLILASMDTNNKGNGVIKSERVEEMQKPVLGENGL
GIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGWVILTNGEGGIDLRQDIYHAWIEYETGELPESYFSLAEQRKTNF
ITSIVIGATLSIYLLLFVIRLYKGRRAFIFKQEKKSYIGLVVRTFLLIITAVLVFCAAYLWRVFSLNSGNTINFILIMAW
IITLLISGFFPKIKSNKKQRMKRKKLTSKFTCM

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790593, Length=248, Percent_Identity=25.4032258064516, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082101, Length=239, Percent_Identity=28.4518828451883, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550934, Length=200, Percent_Identity=30, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533026, Length=383, Percent_Identity=25.8485639686684, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 58174; Mature: 58174

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRQKASIICKSILCFIICIFITSEAWFTNVVRAESGMLTGRSIEDFKKKLDEQVPKWQ
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHH
ENYEVPGVAIGIVHEGRIAYTLNYGYVDKKTKKAVSDDTLFQAGSISKSLTAWGILHLVD
HCCCCCCEEEEEEECCEEEEEEECCCCCHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHC
EGRLLLDDPVGKYLTKWKLPNSEFNNNEVTIRRLLSHTAGLSAHKGYLGVAPGKHLDSIE
CCCEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHH
ESLSGKGWLNEPVEVTKKPGSETIYSGGGYTILQLVMEEVTGISFDRYMEEQIMKPLGMK
HHHCCCCCCCCCHHHHCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
SSSFLQRPENHNLSKAYGYFGEEFPSYQFTEQAAAGLKTNVIDMMTLILASMDTNNKGNG
CHHHHCCCCCCCCHHHHCCHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
VIKSERVEEMQKPVLGENGLGIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGWVIL
CCCHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCCCCEEEE
TNGEGGIDLRQDIYHAWIEYETGELPESYFSLAEQRKTNFITSIVIGATLSIYLLLFVIR
ECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYKGRRAFIFKQEKKSYIGLVVRTFLLIITAVLVFCAAYLWRVFSLNSGNTINFILIMAW
HHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IITLLISGFFPKIKSNKKQRMKRKKLTSKFTCM
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNRQKASIICKSILCFIICIFITSEAWFTNVVRAESGMLTGRSIEDFKKKLDEQVPKWQ
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHH
ENYEVPGVAIGIVHEGRIAYTLNYGYVDKKTKKAVSDDTLFQAGSISKSLTAWGILHLVD
HCCCCCCEEEEEEECCEEEEEEECCCCCHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHC
EGRLLLDDPVGKYLTKWKLPNSEFNNNEVTIRRLLSHTAGLSAHKGYLGVAPGKHLDSIE
CCCEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHH
ESLSGKGWLNEPVEVTKKPGSETIYSGGGYTILQLVMEEVTGISFDRYMEEQIMKPLGMK
HHHCCCCCCCCCHHHHCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
SSSFLQRPENHNLSKAYGYFGEEFPSYQFTEQAAAGLKTNVIDMMTLILASMDTNNKGNG
CHHHHCCCCCCCCHHHHCCHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
VIKSERVEEMQKPVLGENGLGIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGWVIL
CCCHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCCCCEEEE
TNGEGGIDLRQDIYHAWIEYETGELPESYFSLAEQRKTNFITSIVIGATLSIYLLLFVIR
ECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYKGRRAFIFKQEKKSYIGLVVRTFLLIITAVLVFCAAYLWRVFSLNSGNTINFILIMAW
HHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IITLLISGFFPKIKSNKKQRMKRKKLTSKFTCM
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA