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The map label for this gene is arsB [H]

Identifier: 118478483

GI number: 118478483

Start: 3024038

End: 3025090

Strand: Reverse

Name: arsB [H]

Synonym: BALH_2855

Alternate gene names: 118478483

Gene position: 3025090-3024038 (Counterclockwise)

Preceding gene: 118478484

Following gene: 229576699

Centisome position: 57.54

GC content: 35.99

Gene sequence:

>1053_bases
ATGGAAAATAAAATGAAACGTTTATCTTTTCTAGACCGATATTTAACACTATGGATTTTTCTAGCGATGGCTGTTGGGAT
TGGTTTAGGGTTTGTGTTCCCTAGTGTAGTAGACGGACTGAATACATTACAAGTTGGAACGACGTCTATTCCGCTTGCTG
TTGGTTTAATTGCAATGATGTATCCACCATTAGCGAAAGTTCGCTATGAGGAAATGGGCCGAGTATTTAAAGATGTTAAA
GTGTTAGTTTTATCTTTAGTACAAAACTGGATTATTGGTCCGGTACTTATGTTTGTTTTAGCAATTATTTTTCTTCCTGA
TAAACCAGAATACATGGTCGGTCTCATTATGATTGGATTAGCACGTTGCATCGCAATGGTAATTGTTTGGAACGATCTTG
CCGATGGAGATAAAGAGTATGCGGCAGGTTTAGTCGCTTTTAATTCGGTATTCCAAATGCTCTTTTTCTCGGTTTATGCA
TACGTATTTGTAACAGTCATTCCAGAATGGTTAGGGATTGAAGGGGCTATTGTCGATATTACAATGATAGAAGTAGCAAA
ATCAGTATTTATCTATTTAGGAATTCCTTTTATAGCAGGTATGTTGACACGCTTTGTACTCGTTAAGTTAAAAGGAAGAC
AGTGGTATGAAAAGGTATTTATACCGAAGATTAGTCCACTTACATTACTGGCATTGCTATTTACAATCATCATTATGTTT
TCTTTAAAAGGAGAGATGATTGTTAGCGTACCACTAGATGTAGTAAGAATAGCAATTCCATTACTCATTTATTTTATTGT
AATGTTTTTTGTGTCTTTCTTTATGGGAAGAAAGATTGGTGCAAACTATCCGGTAACTACAACATTAGCATTTACAGCAG
GTAGTAATAACTTTGAGTTAGCAATTGCTGTAGCAGTTGGGGTATTTGGCATTCATTCCGGTGCGGCATTCGCAGCTGTT
ATCGGTCCTTTAGTTGAAGTACCTGTAATGATTGCACTTGTAAACGTCGCTTTTTGGTTTAAGCGTAAATATTTTAATGA
TCAATCAGTCTAA

Upstream 100 bases:

>100_bases
CTTTTATACGAAAGCACAGAGTGATGTTCATAAAATTGAAGATCCATCTTGTTGCACGACTTCTAACGTAGTAGAACAAA
ATTCTTGTTGTTAATAGGAG

Downstream 100 bases:

>100_bases
ATTTAAAAATAAAGGTGGAAAACAACATGGAGAACAAAAAGACAATCTATTTCTTATGCACAGGAAATTCATGCCGAAGC
CAAATGGCAGAAGCGTGGGG

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MENKMKRLSFLDRYLTLWIFLAMAVGIGLGFVFPSVVDGLNTLQVGTTSIPLAVGLIAMMYPPLAKVRYEEMGRVFKDVK
VLVLSLVQNWIIGPVLMFVLAIIFLPDKPEYMVGLIMIGLARCIAMVIVWNDLADGDKEYAAGLVAFNSVFQMLFFSVYA
YVFVTVIPEWLGIEGAIVDITMIEVAKSVFIYLGIPFIAGMLTRFVLVKLKGRQWYEKVFIPKISPLTLLALLFTIIIMF
SLKGEMIVSVPLDVVRIAIPLLIYFIVMFFVSFFMGRKIGANYPVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAAV
IGPLVEVPVMIALVNVAFWFKRKYFNDQSV

Sequences:

>Translated_350_residues
MENKMKRLSFLDRYLTLWIFLAMAVGIGLGFVFPSVVDGLNTLQVGTTSIPLAVGLIAMMYPPLAKVRYEEMGRVFKDVK
VLVLSLVQNWIIGPVLMFVLAIIFLPDKPEYMVGLIMIGLARCIAMVIVWNDLADGDKEYAAGLVAFNSVFQMLFFSVYA
YVFVTVIPEWLGIEGAIVDITMIEVAKSVFIYLGIPFIAGMLTRFVLVKLKGRQWYEKVFIPKISPLTLLALLFTIIIMF
SLKGEMIVSVPLDVVRIAIPLLIYFIVMFFVSFFMGRKIGANYPVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAAV
IGPLVEVPVMIALVNVAFWFKRKYFNDQSV
>Mature_350_residues
MENKMKRLSFLDRYLTLWIFLAMAVGIGLGFVFPSVVDGLNTLQVGTTSIPLAVGLIAMMYPPLAKVRYEEMGRVFKDVK
VLVLSLVQNWIIGPVLMFVLAIIFLPDKPEYMVGLIMIGLARCIAMVIVWNDLADGDKEYAAGLVAFNSVFQMLFFSVYA
YVFVTVIPEWLGIEGAIVDITMIEVAKSVFIYLGIPFIAGMLTRFVLVKLKGRQWYEKVFIPKISPLTLLALLFTIIIMF
SLKGEMIVSVPLDVVRIAIPLLIYFIVMFFVSFFMGRKIGANYPVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAAV
IGPLVEVPVMIALVNVAFWFKRKYFNDQSV

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=334, Percent_Identity=35.9281437125749, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38899; Mature: 38899

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]