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The map label for this gene is 118478388

Identifier: 118478388

GI number: 118478388

Start: 2915579

End: 2916154

Strand: Direct

Name: 118478388

Synonym: BALH_2753

Alternate gene names: NA

Gene position: 2915579-2916154 (Clockwise)

Preceding gene: 118478386

Following gene: 118478403

Centisome position: 55.46

GC content: 34.03

Gene sequence:

>576_bases
GTGTGGTTTAAAGATACACACTGGTTCGGTGTTCCAATTTGTAAACTTCCCTCTGATCTCTTTTTGTATCAAGAAATCAT
TTACGAATTAAAGCCCGATTTAATTATTGAATGCGGGACATTTCATGGTGGTAGTGCACTGTATTTAGCTTCTATGTTAG
ATTTAATTGGAAAAGGTCACGTACTTACTATTGATATAACTCCGCAGCCAAATCGACCATCACATAATCGGATTACGTAT
TTAACAGCTTCTTCTGTTTCTGTACAGGCCATCCAAACAATAATAAGTATGCGCAAACCTGATGATGTGATTTTAGTTAT
TTTAGATTCTGATCATAGTAAAGATCATGTATCCAAAGAACTTTTACTATATAAATCTATCGTCACTACTGGAAGTTATA
TGATTGTAGAAGATACCTCTATTAATGGAAATCCGCTTCTTCCCGATTGGGGTCCTGGACCGATGGAAGCGGTTGAAGAG
TTTTTAGCTAAAAATAACAATTTCATAATCGATGAATCTAAGCATAAGTTTTTCATATCATTTAATCCAAAAGGTTTTTT
AAAGAAGATAAAGTGA

Upstream 100 bases:

>100_bases
GTAAACACTTTACGTCAAACGAGAGAATCCTTTATAGAAAGGAGAATTTAAAATCGATAATATAAGCAATGAATTTCTAA
ACCAATATTACGACAGCCTT

Downstream 100 bases:

>100_bases
AACGTTAATAAGTGGGGATAGAGAAAACCCCACTTATTCTATGATCTTCATTTTTGAAAAAGGATAATATACAAATTCCA
CTTTTCCTATTATATTATCT

Product: cephalosporin hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MWFKDTHWFGVPICKLPSDLFLYQEIIYELKPDLIIECGTFHGGSALYLASMLDLIGKGHVLTIDITPQPNRPSHNRITY
LTASSVSVQAIQTIISMRKPDDVILVILDSDHSKDHVSKELLLYKSIVTTGSYMIVEDTSINGNPLLPDWGPGPMEAVEE
FLAKNNNFIIDESKHKFFISFNPKGFLKKIK

Sequences:

>Translated_191_residues
MWFKDTHWFGVPICKLPSDLFLYQEIIYELKPDLIIECGTFHGGSALYLASMLDLIGKGHVLTIDITPQPNRPSHNRITY
LTASSVSVQAIQTIISMRKPDDVILVILDSDHSKDHVSKELLLYKSIVTTGSYMIVEDTSINGNPLLPDWGPGPMEAVEE
FLAKNNNFIIDESKHKFFISFNPKGFLKKIK
>Mature_191_residues
MWFKDTHWFGVPICKLPSDLFLYQEIIYELKPDLIIECGTFHGGSALYLASMLDLIGKGHVLTIDITPQPNRPSHNRITY
LTASSVSVQAIQTIISMRKPDDVILVILDSDHSKDHVSKELLLYKSIVTTGSYMIVEDTSINGNPLLPDWGPGPMEAVEE
FLAKNNNFIIDESKHKFFISFNPKGFLKKIK

Specific function: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD) [H]

COG id: COG3510

COG function: function code V; Cephalosporin hydroxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rhamnosyl O-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007072 [H]

Pfam domain/function: PF04989 CmcI [H]

EC number: NA

Molecular weight: Translated: 21579; Mature: 21579

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFKDTHWFGVPICKLPSDLFLYQEIIYELKPDLIIECGTFHGGSALYLASMLDLIGKGH
CCCCCCCEECCCHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
VLTIDITPQPNRPSHNRITYLTASSVSVQAIQTIISMRKPDDVILVILDSDHSKDHVSKE
EEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHH
LLLYKSIVTTGSYMIVEDTSINGNPLLPDWGPGPMEAVEEFLAKNNNFIIDESKHKFFIS
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEE
FNPKGFLKKIK
ECCCHHHEECC
>Mature Secondary Structure
MWFKDTHWFGVPICKLPSDLFLYQEIIYELKPDLIIECGTFHGGSALYLASMLDLIGKGH
CCCCCCCEECCCHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
VLTIDITPQPNRPSHNRITYLTASSVSVQAIQTIISMRKPDDVILVILDSDHSKDHVSKE
EEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHH
LLLYKSIVTTGSYMIVEDTSINGNPLLPDWGPGPMEAVEEFLAKNNNFIIDESKHKFFIS
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEE
FNPKGFLKKIK
ECCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]