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The map label for this gene is katE [H]

Identifier: 118478346

GI number: 118478346

Start: 2876181

End: 2877632

Strand: Direct

Name: katE [H]

Synonym: BALH_2710

Alternate gene names: 118478346

Gene position: 2876181-2877632 (Clockwise)

Preceding gene: 118478341

Following gene: 118478356

Centisome position: 54.71

GC content: 37.12

Gene sequence:

>1452_bases
GTGTTATACATAATCAAGGCTAAAAAATCATATTTAGTAACAATGAACAAAAAAGATTTGGAGGCTATATTGATGGGTGA
AAACCATGATAAACAGAGGCAATCTTTACTAGGGAAAGACTTTAATGAAAATGGAGAACGTAATGAACAAGCAATCCTTC
ACTCTCAAACAGTTGGTTCACGTGGACCTGTTTTAGAGCAAGATAGTGTGCTTCACGAGGCGTTACAAGAATTTATTCAC
GAAAAAATTTTAGAAAGACCTGTTCATGTAAAAGGATTCGGTGCGTTCGGTTATTTTCAAACGATCTATCCAATGTCCGA
ACATACTAAACTAAGTTTTCTACAACATTCTAATGAGAAAGTTCCTGTTATGGTTCGATTTTCATTAGCTGTTAGTACGA
AAGGAACACCTGACACTGCTAGAAATGTACGTGGTTTTTCTACAAAATTCTATACAAAAGAAGGTATTTTCGATCTATTA
TGTAATCACATTCCTGTCTTTTCTGTTCGCGATCCGATGCGTTTCCCTGAAACCATTCAAGCGTTGTTACCTTCACCTAT
AAACAACTTACTAGACCCGAATAGATTTTGGAGTTTTGTCGCTAGAGCACCTGAATCCATTCATTTTGTTGTCCATTTGT
ACTCTGATAATGGTACGGCCAAAAGCTTTCGCCGCATTCCAGGACATAGTGTAAATACATATGTTTGGAGAAATGCAGAA
GGTAACCGCAAATATGTAAAGTATCATTGGTACCCATTTGAAGGTGTACAATCCATTACTAATGAGGAAGCGAATAAACT
AGCTGCCGAAAACCCTGATTATAGCGGGAAAGATTTATATGATGCAATTGCAAATGGTAAACCAGTGGAATATGGTTTAT
ACGTCCAGCTTATGGACCCGAAAGATGAAGCGCATCTTTCTTACGATCCTTTAGATGATACAAAAGCATGGGATGAAAAA
GCGTATCCTCTTATACCAGTCGGCAAAATGGTATTAAATAAAAACCCTGAAAATTATATGGAACAAGTAGAAAAAGTCGC
TTTCTCCCCTTCTAATTTACTAGACGGCGCAGAATTATCAGATGATAAAATGTTGCAAGGACGTGCAAACATTTATAGTG
ATTCTCAAAGAAGAAGAATTAGTCCTGAATTTCGTAAATTAGCAATTAACCAACAGCAAGATTGGACACCTGCTAATCAA
ATAACGAGCGGTGACGGAAGGTACGTTGAAGGTAAACTTGAGAGAACTTCTATACCGAAACAAGATGACTTTACACAGGC
CGGTGAATTTTATGCGAAGTTACAACCGATAGAAAAAGAACATCTTGCTGAAAACTTAGCTAGTGATTTGAAAGTTATAT
CCGATGATATTAGAAAGGTCGTTTTGGGGTATTTTCATAACGTGTCAGCTGATTTGGTGAAGAGGATTGAAAGTGCGATG
CAACAGCTTTGA

Upstream 100 bases:

>100_bases
TCTTCCCGATATTCATTTTTCCATAATTTCTTCTATTTCAACAGGTCCACTGCATACGCGTTTTTTTCATCTAGCGGTCT
GTTACTATTTTGAGCTTTGC

Downstream 100 bases:

>100_bases
GAATATAAAAAACGTCATTTTCAATCTTTAAAATGACGTTTTTTATGGCGAAATTACTAGGGATTTCTATCGCTTTATTT
ACAATGATTAACGAAATTTT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MLYIIKAKKSYLVTMNKKDLEAILMGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIH
EKILERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLL
CNHIPVFSVRDPMRFPETIQALLPSPINNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAE
GNRKYVKYHWYPFEGVQSITNEEANKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEK
AYPLIPVGKMVLNKNPENYMEQVEKVAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRISPEFRKLAINQQQDWTPANQ
ITSGDGRYVEGKLERTSIPKQDDFTQAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAM
QQL

Sequences:

>Translated_483_residues
MLYIIKAKKSYLVTMNKKDLEAILMGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIH
EKILERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLL
CNHIPVFSVRDPMRFPETIQALLPSPINNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAE
GNRKYVKYHWYPFEGVQSITNEEANKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEK
AYPLIPVGKMVLNKNPENYMEQVEKVAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRISPEFRKLAINQQQDWTPANQ
ITSGDGRYVEGKLERTSIPKQDDFTQAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAM
QQL
>Mature_483_residues
MLYIIKAKKSYLVTMNKKDLEAILMGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIH
EKILERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLL
CNHIPVFSVRDPMRFPETIQALLPSPINNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAE
GNRKYVKYHWYPFEGVQSITNEEANKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEK
AYPLIPVGKMVLNKNPENYMEQVEKVAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRISPEFRKLAINQQQDWTPANQ
ITSGDGRYVEGKLERTSIPKQDDFTQAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAM
QQL

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=461, Percent_Identity=36.4425162689805, Blast_Score=306, Evalue=4e-83,
Organism=Escherichia coli, GI48994891, Length=343, Percent_Identity=40.5247813411079, Blast_Score=272, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71998444, Length=456, Percent_Identity=35.3070175438597, Blast_Score=294, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI25147792, Length=456, Percent_Identity=35.3070175438597, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI25151141, Length=456, Percent_Identity=35.3070175438597, Blast_Score=290, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6320462, Length=339, Percent_Identity=39.8230088495575, Blast_Score=262, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321525, Length=373, Percent_Identity=33.7801608579088, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI17981717, Length=456, Percent_Identity=36.4035087719298, Blast_Score=302, Evalue=4e-82,
Organism=Drosophila melanogaster, GI19920968, Length=335, Percent_Identity=39.7014925373134, Blast_Score=286, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55225; Mature: 55225

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYIIKAKKSYLVTMNKKDLEAILMGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGS
CEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
RGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCCCHHHHHCCCCC
VPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQ
CEEEEEEEEEEECCCCCHHHHCCCCCCEEEECHHHHHHHHHCCCCEEECCCCCCCHHHHH
ALLPSPINNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAE
HHCCCHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEECCC
GNRKYVKYHWYPFEGVQSITNEEANKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDP
CCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEEEEECC
KDEAHLSYDPLDDTKAWDEKAYPLIPVGKMVLNKNPENYMEQVEKVAFSPSNLLDGAELS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
DDKMLQGRANIYSDSQRRRISPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPK
CCHHHCCCCCCCCCCHHCCCCHHHHHHHCCCCCCCCCHHCCCCCCCCEEECEEHHCCCCC
QDDFTQAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAM
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QQL
HCC
>Mature Secondary Structure
MLYIIKAKKSYLVTMNKKDLEAILMGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGS
CEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
RGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCCCHHHHHCCCCC
VPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQ
CEEEEEEEEEEECCCCCHHHHCCCCCCEEEECHHHHHHHHHCCCCEEECCCCCCCHHHHH
ALLPSPINNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAE
HHCCCHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEECCC
GNRKYVKYHWYPFEGVQSITNEEANKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDP
CCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEEEEECC
KDEAHLSYDPLDDTKAWDEKAYPLIPVGKMVLNKNPENYMEQVEKVAFSPSNLLDGAELS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
DDKMLQGRANIYSDSQRRRISPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPK
CCHHHCCCCCCCCCCHHCCCCHHHHHHHCCCCCCCCCHHCCCCCCCCEEECEEHHCCCCC
QDDFTQAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAM
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QQL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]