| Definition | Bacillus thuringiensis str. Al Hakam chromosome, complete genome. |
|---|---|
| Accession | NC_008600 |
| Length | 5,257,091 |
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The map label for this gene is mleN [H]
Identifier: 118477244
GI number: 118477244
Start: 1694937
End: 1696340
Strand: Direct
Name: mleN [H]
Synonym: BALH_1552
Alternate gene names: 118477244
Gene position: 1694937-1696340 (Clockwise)
Preceding gene: 118477243
Following gene: 118477245
Centisome position: 32.24
GC content: 36.04
Gene sequence:
>1404_bases ATGAAAAGTGTAAGATTACCATCGATGGTAGAAATCATAGTTCTTTTATTATTATTTCTTGCTGTTGTCTTTTCCTTCCA AACGATTTTTGATCTCCCAATTCAATTAGCGCTATTTATTTCATGGTTTTTAGTAATTGCGCTTGGATTAAGATTAGGAT TTCGTTATCAAGAATTGCAGGATGCAATTACGAAAGGGATTTCTAACGGATTAGAAGCAATACTCATTTTAGTTGCAGTA GGTGCTTTAATTGGAACATGGATTGCTGGTGGGATAGTACCAACATTAATTTATTATGGATTAGAATTTATTCACCCTAG CATATTCCTATTAGCAACATTAATTATTTGTTCGATAACTTCTATCGCAACAGGAACATCTTGGGGAACGGTAGGAACAG CAGGTATTGCTATGATGGCAATTGGTGAAGGTCTTGGGTTACCATTACCACTTGTTGCTGGTGCAGTTCTTTCAGGTGCT TATTTCGGGGATAAATTATCACCACTTTCTGATAGTACAGTACTTGCAGCATCTATGGCAAAAGTAGATGTTATTGCACA CGTACGAGCTATGCTTGTATTAGACGTTCCAGCGTATATTATCACTAGCATTATGTTTACTGTAGCTGGTTGGATGTATG GCGGAGATAACGTAGATTTAAATCGAGTAGAATTTTTAAAGGAATCATTATTAAAACACTTTGATATTAAAATATGGATG TTAGTTCCGGCGATTATTGTCATTGTACTATTAGCAATGAAGAAGCCTTCTATGCCTACAATTGCAATGGGAGCTTTACT TGGTGCAATTTGGGCAACTGTTTTCCAAGGAATGCACTTTGGAGACGCAATTGGAACAGCATATAACGGATTCTCAATTC AATCAGGCGTTGAGTTTGTCGATAAGTTATTAAACCGTGGCGGAATTAACGGTATGCTCGGTTCAGTAGCCGTAATTATT TTCGGTTTAGGGTTTGGTGGATTACTTGAAAAATTAGGTGTTTTAAAAGTAATCGTATCAAAATTCGAAAAGAAATTAAA TTCTGCTGGTAATGTAACATTATCTACATTAATCGTTGCATTTTTAGCGAACATATTTGGCTGTGCGATGTACGTATCAC TTATTTTAACACCGAAAATTATGCAAGAAAGTTATGATAAACTAAAAATCGACCGCCGCGTATTAGCGCGTAACTCAGAA GTAGGTGGAACATTAACTTCAGGTATGGTTCCATGGTCGGATAACGGTATTTTTATGGCTGGTATTTTAGGTGTTGCGAC GATATCATACATTCCATTTATGTGGTTAAGCTTCGTATCGTTAATTTTAGCAGTTATTTACGGATATACAGGCAAGTTCA TTTGGTATGTAGATGATGCTGAAAAAGGAAAAGAAGCGTCATAA
Upstream 100 bases:
>100_bases TCGAAATAATATGAAAATTTTGTTTTGTCTTCGCTAATTGTATACTGCATATACGTAAGACGACATACATCATGTTATCG ACTTGTAAGGAGAGAAAAAA
Downstream 100 bases:
>100_bases ATAAAAAATCACCTTCTGCGTGTTGTAGAAGGTGATTTTTTATTATGAAAGCATATTTTTTCATATTGAATTCCTCCAGT AGTGTTATAGTAGGTTACAA
Product: Na+/H+ antiporter
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 467; Mature: 467
Protein sequence:
>467_residues MKSVRLPSMVEIIVLLLLFLAVVFSFQTIFDLPIQLALFISWFLVIALGLRLGFRYQELQDAITKGISNGLEAILILVAV GALIGTWIAGGIVPTLIYYGLEFIHPSIFLLATLIICSITSIATGTSWGTVGTAGIAMMAIGEGLGLPLPLVAGAVLSGA YFGDKLSPLSDSTVLAASMAKVDVIAHVRAMLVLDVPAYIITSIMFTVAGWMYGGDNVDLNRVEFLKESLLKHFDIKIWM LVPAIIVIVLLAMKKPSMPTIAMGALLGAIWATVFQGMHFGDAIGTAYNGFSIQSGVEFVDKLLNRGGINGMLGSVAVII FGLGFGGLLEKLGVLKVIVSKFEKKLNSAGNVTLSTLIVAFLANIFGCAMYVSLILTPKIMQESYDKLKIDRRVLARNSE VGGTLTSGMVPWSDNGIFMAGILGVATISYIPFMWLSFVSLILAVIYGYTGKFIWYVDDAEKGKEAS
Sequences:
>Translated_467_residues MKSVRLPSMVEIIVLLLLFLAVVFSFQTIFDLPIQLALFISWFLVIALGLRLGFRYQELQDAITKGISNGLEAILILVAV GALIGTWIAGGIVPTLIYYGLEFIHPSIFLLATLIICSITSIATGTSWGTVGTAGIAMMAIGEGLGLPLPLVAGAVLSGA YFGDKLSPLSDSTVLAASMAKVDVIAHVRAMLVLDVPAYIITSIMFTVAGWMYGGDNVDLNRVEFLKESLLKHFDIKIWM LVPAIIVIVLLAMKKPSMPTIAMGALLGAIWATVFQGMHFGDAIGTAYNGFSIQSGVEFVDKLLNRGGINGMLGSVAVII FGLGFGGLLEKLGVLKVIVSKFEKKLNSAGNVTLSTLIVAFLANIFGCAMYVSLILTPKIMQESYDKLKIDRRVLARNSE VGGTLTSGMVPWSDNGIFMAGILGVATISYIPFMWLSFVSLILAVIYGYTGKFIWYVDDAEKGKEAS >Mature_467_residues MKSVRLPSMVEIIVLLLLFLAVVFSFQTIFDLPIQLALFISWFLVIALGLRLGFRYQELQDAITKGISNGLEAILILVAV GALIGTWIAGGIVPTLIYYGLEFIHPSIFLLATLIICSITSIATGTSWGTVGTAGIAMMAIGEGLGLPLPLVAGAVLSGA YFGDKLSPLSDSTVLAASMAKVDVIAHVRAMLVLDVPAYIITSIMFTVAGWMYGGDNVDLNRVEFLKESLLKHFDIKIWM LVPAIIVIVLLAMKKPSMPTIAMGALLGAIWATVFQGMHFGDAIGTAYNGFSIQSGVEFVDKLLNRGGINGMLGSVAVII FGLGFGGLLEKLGVLKVIVSKFEKKLNSAGNVTLSTLIVAFLANIFGCAMYVSLILTPKIMQESYDKLKIDRRVLARNSE VGGTLTSGMVPWSDNGIFMAGILGVATISYIPFMWLSFVSLILAVIYGYTGKFIWYVDDAEKGKEAS
Specific function: Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport, in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force [H]
COG id: COG1757
COG function: function code C; Na+/H+ antiporter
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004770 - InterPro: IPR018461 [H]
Pfam domain/function: PF03553 Na_H_antiporter [H]
EC number: NA
Molecular weight: Translated: 50105; Mature: 50105
Theoretical pI: Translated: 7.55; Mature: 7.55
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKSVRLPSMVEIIVLLLLFLAVVFSFQTIFDLPIQLALFISWFLVIALGLRLGFRYQELQ CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH DAITKGISNGLEAILILVAVGALIGTWIAGGIVPTLIYYGLEFIHPSIFLLATLIICSIT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIATGTSWGTVGTAGIAMMAIGEGLGLPLPLVAGAVLSGAYFGDKLSPLSDSTVLAASMA HHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH KVDVIAHVRAMLVLDVPAYIITSIMFTVAGWMYGGDNVDLNRVEFLKESLLKHFDIKIWM HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHH LVPAIIVIVLLAMKKPSMPTIAMGALLGAIWATVFQGMHFGDAIGTAYNGFSIQSGVEFV HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHH DKLLNRGGINGMLGSVAVIIFGLGFGGLLEKLGVLKVIVSKFEKKLNSAGNVTLSTLIVA HHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH FLANIFGCAMYVSLILTPKIMQESYDKLKIDRRVLARNSEVGGTLTSGMVPWSDNGIFMA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHH GILGVATISYIPFMWLSFVSLILAVIYGYTGKFIWYVDDAEKGKEAS HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC >Mature Secondary Structure MKSVRLPSMVEIIVLLLLFLAVVFSFQTIFDLPIQLALFISWFLVIALGLRLGFRYQELQ CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH DAITKGISNGLEAILILVAVGALIGTWIAGGIVPTLIYYGLEFIHPSIFLLATLIICSIT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIATGTSWGTVGTAGIAMMAIGEGLGLPLPLVAGAVLSGAYFGDKLSPLSDSTVLAASMA HHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH KVDVIAHVRAMLVLDVPAYIITSIMFTVAGWMYGGDNVDLNRVEFLKESLLKHFDIKIWM HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHH LVPAIIVIVLLAMKKPSMPTIAMGALLGAIWATVFQGMHFGDAIGTAYNGFSIQSGVEFV HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHH DKLLNRGGINGMLGSVAVIIFGLGFGGLLEKLGVLKVIVSKFEKKLNSAGNVTLSTLIVA HHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH FLANIFGCAMYVSLILTPKIMQESYDKLKIDRRVLARNSEVGGTLTSGMVPWSDNGIFMA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHH GILGVATISYIPFMWLSFVSLILAVIYGYTGKFIWYVDDAEKGKEAS HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8969508; 9384377; 10903309 [H]