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The map label for this gene is hup [H]

Identifier: 118477063

GI number: 118477063

Start: 1506622

End: 1506975

Strand: Direct

Name: hup [H]

Synonym: BALH_1364

Alternate gene names: 118477063

Gene position: 1506622-1506975 (Clockwise)

Preceding gene: 118477062

Following gene: 118477064

Centisome position: 28.66

GC content: 38.98

Gene sequence:

>354_bases
TTGCAAAAATTGCCTACAAATGAAAGTAAGACTCATTTTATGATCATTATACAGTCTTATCTTTGGGAGGAGGTGAATGG
CATGAACAAGACAGATTTAATCAATGCTGTTGCAGAAGCAAGTTCCCTTTCTAAAAAGGACGCAACAAAAGCAGTAGACG
CTGTTTTTGATTCTATCTTAGAAGCTTTAAAACAAGGTGATAAAGTACAACTGATCGGATTCGGTAACTTCGAAGTTCGT
GAGCGTGCGGCTCGTAAAGGTCGTAACCCACAAACAGGTGAGGAGATTGAAATCGCTGCAAGTAAAGTACCTGCATTCAA
ACCTGGTAAAGCGTTAAAAGATGCGGTTAAATAA

Upstream 100 bases:

>100_bases
TTTTAAGAGTAACAATTTCCTTAAAAATATTGAATTATAAAGGAGAATCGTATAATATAGGCGTTGATAATGATTTATCT
ACATCTTTGTAGTATAGAAT

Downstream 100 bases:

>100_bases
TCCTTACATATTAACAGGGAAGAAGAGTTTCCTTTTTGGAAACTCTTCTTTTTGCTTTTAAAAACATAAATATGCTAGAA
TGTGTTCGTATCACTTTTAG

Product: DNA-binding protein HU

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MQKLPTNESKTHFMIIIQSYLWEEVNGMNKTDLINAVAEASSLSKKDATKAVDAVFDSILEALKQGDKVQLIGFGNFEVR
ERAARKGRNPQTGEEIEIAASKVPAFKPGKALKDAVK

Sequences:

>Translated_117_residues
MQKLPTNESKTHFMIIIQSYLWEEVNGMNKTDLINAVAEASSLSKKDATKAVDAVFDSILEALKQGDKVQLIGFGNFEVR
ERAARKGRNPQTGEEIEIAASKVPAFKPGKALKDAVK
>Mature_117_residues
MQKLPTNESKTHFMIIIQSYLWEEVNGMNKTDLINAVAEASSLSKKDATKAVDAVFDSILEALKQGDKVQLIGFGNFEVR
ERAARKGRNPQTGEEIEIAASKVPAFKPGKALKDAVK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=60.6741573033708, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=61.1111111111111, Blast_Score=112, Evalue=4e-27,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=42.6966292134831, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=39.7727272727273, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 12862; Mature: 12862

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLPTNESKTHFMIIIQSYLWEEVNGMNKTDLINAVAEASSLSKKDATKAVDAVFDSIL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EALKQGDKVQLIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKPGKALKDAVK
HHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCC
>Mature Secondary Structure
MQKLPTNESKTHFMIIIQSYLWEEVNGMNKTDLINAVAEASSLSKKDATKAVDAVFDSIL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EALKQGDKVQLIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKPGKALKDAVK
HHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644313 [H]