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The map label for this gene is amaA [H]

Identifier: 118476940

GI number: 118476940

Start: 1383223

End: 1384464

Strand: Direct

Name: amaA [H]

Synonym: BALH_1232

Alternate gene names: 118476940

Gene position: 1383223-1384464 (Clockwise)

Preceding gene: 118476935

Following gene: 118476941

Centisome position: 26.31

GC content: 38.16

Gene sequence:

>1242_bases
TTGTTTTTATTAATCACTCGAGACAGAGTAAAGTTTACAATTTCTATCTCTTTTGAAAAGGAGGAAATTATCATGAATAG
AGTGTGGAAGAGTTTAATTGCGGAAGAAAATATCGTGAAATGGAGAAGACATTTTCATAAGTATCCGGAATTATCGTTTC
ATGAGAAAGAAACTTCACAATTTATATATGATACATTATGCGCATTTTCTTCTTTTGAAGTAACGAGACCGACGAAGTAT
AGTGTACTAGCAATTAAAAGAGGAACGGAACAAGGGAAAGTAGTTGCGATTCGAGCTGATATAGATGCTCTGCCAATTCA
AGAGGAGACAAGTAAATCTTATACGTCTGTGAATAAAGGAATGATGCATGCATGTGGGCATGATGCTCACGCAGCTATTT
TGTTAAGTACAGCAGAGGCATTATCAAATATAAAGGAAGATTTTGCAGGGGAGATTCGTCTATTTTTTCAGCACGCAGAA
GAGGTATATCCCGGCGGAGGACGAGAAATGGTTGAGGCAGGCGTGATGGACGGTGTTGATTATGTAATAGGTTTACATGT
TATGTCAGGACTTGAGAGCGGGAAGATAGGAATTGCATATGGGCCGATGATGGCGGCACCAGACGTATTTACAGTTGAAA
TTCAAGGGAAAGGGGGACATGCGGCGAGACCGGAGGAAACGATAGATCCTATTGCTATCGGAGCGCAGATTATTACAAAT
CTACAACATATTGTATCAAGAAATACAAGTGCTTTCATGCAAAGAGTTGTTTCAGTTACGCAGTTTCATGGGGGAATGGC
TGATAATATTATTCCTAGTGCAGCAACTTTAATGGGCACTGTTCGTTCATTTAATCAAGCATTAAGGGTGGAAGCAGAAG
AGAAAATTGAAAAAATCGTGAAAGGCATTACAAAAGCGCATGGAGGGGCGTATACATATACGTATCGATATGGATATGAT
CCAGTGATTAATGATGAATATATTACGAAAGTAGTAGAAGAAAGTGCAATACACTTGTTTGGGAATGAGCGTGTTGTGAA
GCTTGAACCTTCTATGGGAGGAGAAGATTTTTCAGCATATTTAAGAAAAGCACCTGGTTGTTTTATTAAACTAGGAACTG
GTAATGAAAGGATAAATACTTGCTATCCGCATCATCATCCAAAATTTGATGTAGATGAATCAGCGCTAATTAGTGGAGTG
GAATTATTTTTAGAGACAACGATAAGACTACTAAAATCATAG

Upstream 100 bases:

>100_bases
TACATTCAGCATGAATTTGTAATGGGTTTGACATGTAAATAGGAAGCGGATTGTATGAATACATAAAAGTGGACTATAAG
AATACGGAAAAATAGAGTAT

Downstream 100 bases:

>100_bases
AGAAATATAAAAAAAGGCAACTGCGCTCTATCGCAGTTGCTTTTATTTCTTTCCGTCAGAGAGGGCTGAGAAAGAACTAT
GCTCATTTATAGTATATGAA

Product: aminoacylase (N-acyl-L-amino acid amidohydrolase)

Products: NA

Alternate protein names: L-aminoacylase [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MFLLITRDRVKFTISISFEKEEIIMNRVWKSLIAEENIVKWRRHFHKYPELSFHEKETSQFIYDTLCAFSSFEVTRPTKY
SVLAIKRGTEQGKVVAIRADIDALPIQEETSKSYTSVNKGMMHACGHDAHAAILLSTAEALSNIKEDFAGEIRLFFQHAE
EVYPGGGREMVEAGVMDGVDYVIGLHVMSGLESGKIGIAYGPMMAAPDVFTVEIQGKGGHAARPEETIDPIAIGAQIITN
LQHIVSRNTSAFMQRVVSVTQFHGGMADNIIPSAATLMGTVRSFNQALRVEAEEKIEKIVKGITKAHGGAYTYTYRYGYD
PVINDEYITKVVEESAIHLFGNERVVKLEPSMGGEDFSAYLRKAPGCFIKLGTGNERINTCYPHHHPKFDVDESALISGV
ELFLETTIRLLKS

Sequences:

>Translated_413_residues
MFLLITRDRVKFTISISFEKEEIIMNRVWKSLIAEENIVKWRRHFHKYPELSFHEKETSQFIYDTLCAFSSFEVTRPTKY
SVLAIKRGTEQGKVVAIRADIDALPIQEETSKSYTSVNKGMMHACGHDAHAAILLSTAEALSNIKEDFAGEIRLFFQHAE
EVYPGGGREMVEAGVMDGVDYVIGLHVMSGLESGKIGIAYGPMMAAPDVFTVEIQGKGGHAARPEETIDPIAIGAQIITN
LQHIVSRNTSAFMQRVVSVTQFHGGMADNIIPSAATLMGTVRSFNQALRVEAEEKIEKIVKGITKAHGGAYTYTYRYGYD
PVINDEYITKVVEESAIHLFGNERVVKLEPSMGGEDFSAYLRKAPGCFIKLGTGNERINTCYPHHHPKFDVDESALISGV
ELFLETTIRLLKS
>Mature_413_residues
MFLLITRDRVKFTISISFEKEEIIMNRVWKSLIAEENIVKWRRHFHKYPELSFHEKETSQFIYDTLCAFSSFEVTRPTKY
SVLAIKRGTEQGKVVAIRADIDALPIQEETSKSYTSVNKGMMHACGHDAHAAILLSTAEALSNIKEDFAGEIRLFFQHAE
EVYPGGGREMVEAGVMDGVDYVIGLHVMSGLESGKIGIAYGPMMAAPDVFTVEIQGKGGHAARPEETIDPIAIGAQIITN
LQHIVSRNTSAFMQRVVSVTQFHGGMADNIIPSAATLMGTVRSFNQALRVEAEEKIEKIVKGITKAHGGAYTYTYRYGYD
PVINDEYITKVVEESAIHLFGNERVVKLEPSMGGEDFSAYLRKAPGCFIKLGTGNERINTCYPHHHPKFDVDESALISGV
ELFLETTIRLLKS

Specific function: Hydrolyzes most efficiently N-acetyl derivatives of aromatic amino acids but is also active on other amino acids. L- stereospecific [H]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=426, Percent_Identity=25.5868544600939, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.14 [H]

Molecular weight: Translated: 46004; Mature: 46004

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLITRDRVKFTISISFEKEEIIMNRVWKSLIAEENIVKWRRHFHKYPELSFHEKETSQ
CEEEEEECCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FIYDTLCAFSSFEVTRPTKYSVLAIKRGTEQGKVVAIRADIDALPIQEETSKSYTSVNKG
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
MMHACGHDAHAAILLSTAEALSNIKEDFAGEIRLFFQHAEEVYPGGGREMVEAGVMDGVD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
YVIGLHVMSGLESGKIGIAYGPMMAAPDVFTVEIQGKGGHAARPEETIDPIAIGAQIITN
HHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LQHIVSRNTSAFMQRVVSVTQFHGGMADNIIPSAATLMGTVRSFNQALRVEAEEKIEKIV
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KGITKAHGGAYTYTYRYGYDPVINDEYITKVVEESAIHLFGNERVVKLEPSMGGEDFSAY
HHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHH
LRKAPGCFIKLGTGNERINTCYPHHHPKFDVDESALISGVELFLETTIRLLKS
HHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFLLITRDRVKFTISISFEKEEIIMNRVWKSLIAEENIVKWRRHFHKYPELSFHEKETSQ
CEEEEEECCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FIYDTLCAFSSFEVTRPTKYSVLAIKRGTEQGKVVAIRADIDALPIQEETSKSYTSVNKG
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
MMHACGHDAHAAILLSTAEALSNIKEDFAGEIRLFFQHAEEVYPGGGREMVEAGVMDGVD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
YVIGLHVMSGLESGKIGIAYGPMMAAPDVFTVEIQGKGGHAARPEETIDPIAIGAQIITN
HHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LQHIVSRNTSAFMQRVVSVTQFHGGMADNIIPSAATLMGTVRSFNQALRVEAEEKIEKIV
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KGITKAHGGAYTYTYRYGYDPVINDEYITKVVEESAIHLFGNERVVKLEPSMGGEDFSAY
HHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHH
LRKAPGCFIKLGTGNERINTCYPHHHPKFDVDESALISGVELFLETTIRLLKS
HHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8285691; 9023955 [H]