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The map label for this gene is lepB [H]

Identifier: 118476724

GI number: 118476724

Start: 1150626

End: 1151189

Strand: Direct

Name: lepB [H]

Synonym: BALH_1004

Alternate gene names: 118476724

Gene position: 1150626-1151189 (Clockwise)

Preceding gene: 118476723

Following gene: 118476725

Centisome position: 21.89

GC content: 35.82

Gene sequence:

>564_bases
ATGAAGAAAACTTTGAAAAAAGAAGGCATAGAGTGGATACGAACAATTTTAATTGGTGTATTATTAGCTGTATTTTTTCG
AACGTTTTTCTTTTCAACGTACGTTGTAGAGGGGAAATCAATGATGCCGACATTGCAAGATGGCAATATGCTCGTTGTAA
ATAAGGTGAGTTATCATGTGGGGGACTTGAATAGATTTGACGTTGTTGTGTTTCATGCGAACAAAAAAGAGGATTACGTA
AAACGAATTATCGGTTTACCTGGGGATCATATTGAATATAAGCATGATAAGCTATATGTAAATGGACAATTCGTAGATGA
ACCTTATTTAGAGACGTATAAGAAAGAGATAGATGGACGACAACTAACAGGTGATTTTAAACTAGAAGAGTTAACGAAGG
AAAAATCGGTGCCACCTGGATATATTTTTGTAGTGGGTGATAACCGTCTCGGAAGCTGGGATAGTAGACACTTTGGTTTT
GTAAAAGCTGATACAGTTGTCGGTAAAGTTGATTTACGATATTGGCCAATTCAAGATGTGCAAACGAATTTTTCAAAAGG
TTGA

Upstream 100 bases:

>100_bases
GGTATGTCGGTAAGAAAATCGAAGTAAAGTTAGAACTTCATTAAGAATAGTCTTCTTTGTAAAGGAAAGCTTCATTATTA
AAGGAGAAGGGGAGAAGCGG

Downstream 100 bases:

>100_bases
TATAATAGGTAGAAGTATAGAAAAAGACAAACTACTCTGTTTGTCTTTTTTCGTGTCCTATAATACAATTATAGTAGCAA
ACTAACGTTCGTTATGTAAG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKKTLKKEGIEWIRTILIGVLLAVFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYHVGDLNRFDVVVFHANKKEDYV
KRIIGLPGDHIEYKHDKLYVNGQFVDEPYLETYKKEIDGRQLTGDFKLEELTKEKSVPPGYIFVVGDNRLGSWDSRHFGF
VKADTVVGKVDLRYWPIQDVQTNFSKG

Sequences:

>Translated_187_residues
MKKTLKKEGIEWIRTILIGVLLAVFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYHVGDLNRFDVVVFHANKKEDYV
KRIIGLPGDHIEYKHDKLYVNGQFVDEPYLETYKKEIDGRQLTGDFKLEELTKEKSVPPGYIFVVGDNRLGSWDSRHFGF
VKADTVVGKVDLRYWPIQDVQTNFSKG
>Mature_187_residues
MKKTLKKEGIEWIRTILIGVLLAVFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYHVGDLNRFDVVVFHANKKEDYV
KRIIGLPGDHIEYKHDKLYVNGQFVDEPYLETYKKEIDGRQLTGDFKLEELTKEKSVPPGYIFVVGDNRLGSWDSRHFGF
VKADTVVGKVDLRYWPIQDVQTNFSKG

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21664; Mature: 21664

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLKKEGIEWIRTILIGVLLAVFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYHV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCEEEEEEEEEEE
GDLNRFDVVVFHANKKEDYVKRIIGLPGDHIEYKHDKLYVNGQFVDEPYLETYKKEIDGR
CCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEECCEEEECCEECCCHHHHHHHHHCCCC
QLTGDFKLEELTKEKSVPPGYIFVVGDNRLGSWDSRHFGFVKADTVVGKVDLRYWPIQDV
EECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEECEEEEEEEEEEECCHHH
QTNFSKG
CCCCCCC
>Mature Secondary Structure
MKKTLKKEGIEWIRTILIGVLLAVFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYHV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCEEEEEEEEEEE
GDLNRFDVVVFHANKKEDYVKRIIGLPGDHIEYKHDKLYVNGQFVDEPYLETYKKEIDGR
CCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEECCEEEECCEECCCHHHHHHHHHCCCC
QLTGDFKLEELTKEKSVPPGYIFVVGDNRLGSWDSRHFGFVKADTVVGKVDLRYWPIQDV
EECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEECEEEEEEEEEEECCHHH
QTNFSKG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]