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The map label for this gene is pip [H]

Identifier: 118476677

GI number: 118476677

Start: 1098566

End: 1099378

Strand: Direct

Name: pip [H]

Synonym: BALH_0955

Alternate gene names: 118476677

Gene position: 1098566-1099378 (Clockwise)

Preceding gene: 118476676

Following gene: 118476679

Centisome position: 20.9

GC content: 33.83

Gene sequence:

>813_bases
ATGAGGGTAAATGGTAATAATCTTTTTGTAAAAGTATTAGGACAAGGTGAGCCTATTGTGTTTCTTCATGGAGGGCCTGG
AAGTGAGCATCGCTTTTTTCTTCCGTATATGACTCCGCTAGCAGAAAAATTTCAACTAGTTTTTTATGATCAAACAGGTT
GCGGAGAATCGGAAAAGGCGGAGGATAGCCAATATTCTATGCAGAATGAGGTTGAAAACTTAGAAGCTTTGCGTGTGCAA
TTAGGGTTTGAAAAAATAAATATATTAGGTGAATCATGGGGATCGATGCTTGCGTTATTATATGCAACTACATATCCTGA
ACGAGTGAATAAATTACTTTTAACAGCTGCGATAGGGGTTAATGTGACAGGATTAGAAAGATTTGGAGAAGAACTGCAAA
AGAGATTAACGGAAGAAGATAAAGTAGTTATTTCTGAAATAAACGAGAAGATTAAAATAGGAGAGGCTTCTATATACGAT
ATGTTACAAGTGTTAGATCCGTATTATGTGTTTACTATGGAAACTTTAACTTATAAACAGAAAACAACTTTTAGTAATGA
AGTGAACACGACAATAGGTGCAGATATGGTGAAAAATTATGATGTGACTAAGCATGTAGAAAAACTCTCAAAAATTCCAA
TATTAATTGCACAAGGAAGTCATGATATTTTAACTCTTGCTATTATAAAAGAACATTTTACAGAATACATACCTCATATA
GAATTTTTAGAGATTGCAAATTGCGGACATTGGACGGTAGTGGAGCAACCAGAAAAAATGTGTAATATCGCATATAGTTT
TTTCAAGAACTGA

Upstream 100 bases:

>100_bases
TATTTCATTATGTTTAGTTGTAGGTAGTAAAGCGATTTACTTTGTAGCGGTTGTTATTTTATGGGGAGTGGCAGGTACGC
CGTGAAGGGGAGGATGACAT

Downstream 100 bases:

>100_bases
TAATAAGAGCGTAATTCCCTAAGCTAACTTAGAGAATTACGCTCTTATTCGTTCAACGATTTAGTCTGAAATTGCTTGAA
ACGATTTTCTGCACCGATCT

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRVNGNNLFVKVLGQGEPIVFLHGGPGSEHRFFLPYMTPLAEKFQLVFYDQTGCGESEKAEDSQYSMQNEVENLEALRVQ
LGFEKINILGESWGSMLALLYATTYPERVNKLLLTAAIGVNVTGLERFGEELQKRLTEEDKVVISEINEKIKIGEASIYD
MLQVLDPYYVFTMETLTYKQKTTFSNEVNTTIGADMVKNYDVTKHVEKLSKIPILIAQGSHDILTLAIIKEHFTEYIPHI
EFLEIANCGHWTVVEQPEKMCNIAYSFFKN

Sequences:

>Translated_270_residues
MRVNGNNLFVKVLGQGEPIVFLHGGPGSEHRFFLPYMTPLAEKFQLVFYDQTGCGESEKAEDSQYSMQNEVENLEALRVQ
LGFEKINILGESWGSMLALLYATTYPERVNKLLLTAAIGVNVTGLERFGEELQKRLTEEDKVVISEINEKIKIGEASIYD
MLQVLDPYYVFTMETLTYKQKTTFSNEVNTTIGADMVKNYDVTKHVEKLSKIPILIAQGSHDILTLAIIKEHFTEYIPHI
EFLEIANCGHWTVVEQPEKMCNIAYSFFKN
>Mature_270_residues
MRVNGNNLFVKVLGQGEPIVFLHGGPGSEHRFFLPYMTPLAEKFQLVFYDQTGCGESEKAEDSQYSMQNEVENLEALRVQ
LGFEKINILGESWGSMLALLYATTYPERVNKLLLTAAIGVNVTGLERFGEELQKRLTEEDKVVISEINEKIKIGEASIYD
MLQVLDPYYVFTMETLTYKQKTTFSNEVNTTIGADMVKNYDVTKHVEKLSKIPILIAQGSHDILTLAIIKEHFTEYIPHI
EFLEIANCGHWTVVEQPEKMCNIAYSFFKN

Specific function: Characterized by a high specificity towards di- or tripeptides with proline at the NH(2)-terminal position, but is not able to hydrolyze longer peptides, or peptides with hydroxyproline at the NH(2)-end [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cell envelope [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 30750; Mature: 30750

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNGNNLFVKVLGQGEPIVFLHGGPGSEHRFFLPYMTPLAEKFQLVFYDQTGCGESEKA
CEECCCEEEEEEECCCCCEEEEECCCCCCCEEECHHHHHHHHCEEEEEEECCCCCCCCCC
EDSQYSMQNEVENLEALRVQLGFEKINILGESWGSMLALLYATTYPERVNKLLLTAAIGV
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
NVTGLERFGEELQKRLTEEDKVVISEINEKIKIGEASIYDMLQVLDPYYVFTMETLTYKQ
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCHHHHHHHHHHCCEEEEEEHHHHHHH
KTTFSNEVNTTIGADMVKNYDVTKHVEKLSKIPILIAQGSHDILTLAIIKEHFTEYIPHI
HCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHCCCE
EFLEIANCGHWTVVEQPEKMCNIAYSFFKN
EEEEECCCCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVNGNNLFVKVLGQGEPIVFLHGGPGSEHRFFLPYMTPLAEKFQLVFYDQTGCGESEKA
CEECCCEEEEEEECCCCCEEEEECCCCCCCEEECHHHHHHHHCEEEEEEECCCCCCCCCC
EDSQYSMQNEVENLEALRVQLGFEKINILGESWGSMLALLYATTYPERVNKLLLTAAIGV
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
NVTGLERFGEELQKRLTEEDKVVISEINEKIKIGEASIYDMLQVLDPYYVFTMETLTYKQ
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCHHHHHHHHHHCCEEEEEEHHHHHHH
KTTFSNEVNTTIGADMVKNYDVTKHVEKLSKIPILIAQGSHDILTLAIIKEHFTEYIPHI
HCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHCCCE
EFLEIANCGHWTVVEQPEKMCNIAYSFFKN
EEEEECCCCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8012575; 8012576 [H]