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The map label for this gene is appB [H]

Identifier: 118476546

GI number: 118476546

Start: 936301

End: 937251

Strand: Direct

Name: appB [H]

Synonym: BALH_0817

Alternate gene names: 118476546

Gene position: 936301-937251 (Clockwise)

Preceding gene: 118476545

Following gene: 118476547

Centisome position: 17.81

GC content: 36.91

Gene sequence:

>951_bases
GTGTATAAAGTAATTGCGAAGAGGCTTTTAAATGCAATTCCGCTTTTATTTGTTATTTCTATTATTTCTTTTCTATTAAT
AAAACTAGCACCGGGTGATCCTGTTCGAAACTTTGTCACGCCGAATATGAGCCCAATTGATGTTGAGCGTATTCGCACAA
GTTTAGGGTTAGATCAACCAATTTATATGCAGTATATTTTATGGTTGAAAAATATTTTAACAGGGAACTTTGGTTATTCA
CTTCAAAACCATCGTCCTGTTTTAGATCTTATTGTAGAAAGGTTACCTGCGACAATCGGCTTAATGGGATCTTCTTTACT
CGTCTCATTTGTAATCGCAATCCCGCTTGGACTACTTACAGGTGTGAAAAAGAATTCTATCTTTGATCGCATTGTGAACT
TTATCTCCTATGTGGGAATTTCAATGCCAGTCTTTTGGTTCGCTTTACTATTAATTTACTTATTCTCTTTAAAGTTGAAC
CTTCTTCCGAGCATGGGTATGCGCACAGTCGGTCAAGATTCCGTCTGGGATATTGTCCAGCACGGCATTTTACCTTGTAT
GGTGCTAGCGTTCCAAAACGTCTCTGTTTATATGAGATATATTCGTTCCAGTACAATTCAGCAATTAGAAGAAGACTATG
TACAAATTCAATATGCGTACGGTGCTTCGAAGAAAACAGTTTTATATAATCACGTACTTCGAAACGTATTAATACCGATC
ATTACAATTTTCGGATTATCTATTCCAAGTTTAGTAGGCGGAGCGTTCATTACGGAAACAGTATTCTCATGGCCAGGTCT
TGGTTCGCTCGGGGTAAATGCTATTTTTAGATTTGATTATCCGATTATCATGGCAATTACATTATTATCATCATTCATGT
TGATTCTTGGTAACTTAATTGCTGATATTTTATATGGCGTAGTAGATCCGCGCATTCGAATGAGGGGGTGA

Upstream 100 bases:

>100_bases
GTCACAATGTTTGAAGATTTATCTAAGATTTATGAAGTGAAATAAGAAACAATAAAGAAGCTGGTGGAAATCAGCTTCTT
TAGCTTGAGGGGGGAAGTTT

Downstream 100 bases:

>100_bases
TTTGGAATGAATAATAGGAGATTTCAAACGATAAAGCATAGTTTTACAAAAAATAAGTTTGTTGCAATGGGAGTTATTAT
ACTTGCGGTTTTAACGGTCG

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRTSLGLDQPIYMQYILWLKNILTGNFGYS
LQNHRPVLDLIVERLPATIGLMGSSLLVSFVIAIPLGLLTGVKKNSIFDRIVNFISYVGISMPVFWFALLLIYLFSLKLN
LLPSMGMRTVGQDSVWDIVQHGILPCMVLAFQNVSVYMRYIRSSTIQQLEEDYVQIQYAYGASKKTVLYNHVLRNVLIPI
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLIADILYGVVDPRIRMRG

Sequences:

>Translated_316_residues
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRTSLGLDQPIYMQYILWLKNILTGNFGYS
LQNHRPVLDLIVERLPATIGLMGSSLLVSFVIAIPLGLLTGVKKNSIFDRIVNFISYVGISMPVFWFALLLIYLFSLKLN
LLPSMGMRTVGQDSVWDIVQHGILPCMVLAFQNVSVYMRYIRSSTIQQLEEDYVQIQYAYGASKKTVLYNHVLRNVLIPI
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLIADILYGVVDPRIRMRG
>Mature_316_residues
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRTSLGLDQPIYMQYILWLKNILTGNFGYS
LQNHRPVLDLIVERLPATIGLMGSSLLVSFVIAIPLGLLTGVKKNSIFDRIVNFISYVGISMPVFWFALLLIYLFSLKLN
LLPSMGMRTVGQDSVWDIVQHGILPCMVLAFQNVSVYMRYIRSSTIQQLEEDYVQIQYAYGASKKTVLYNHVLRNVLIPI
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLIADILYGVVDPRIRMRG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=315, Percent_Identity=39.6825396825397, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=37.9746835443038, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=35.7988165680473, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=34.9253731343284, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787497, Length=316, Percent_Identity=30.0632911392405, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=32.3529411764706, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1788504, Length=357, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35453; Mature: 35453

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRTSLGLDQP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCH
IYMQYILWLKNILTGNFGYSLQNHRPVLDLIVERLPATIGLMGSSLLVSFVIAIPLGLLT
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVKKNSIFDRIVNFISYVGISMPVFWFALLLIYLFSLKLNLLPSMGMRTVGQDSVWDIVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
HGILPCMVLAFQNVSVYMRYIRSSTIQQLEEDYVQIQYAYGASKKTVLYNHVLRNVLIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCHHHHHHHHHHHHHHHH
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ADILYGVVDPRIRMRG
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRTSLGLDQP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCH
IYMQYILWLKNILTGNFGYSLQNHRPVLDLIVERLPATIGLMGSSLLVSFVIAIPLGLLT
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVKKNSIFDRIVNFISYVGISMPVFWFALLLIYLFSLKLNLLPSMGMRTVGQDSVWDIVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
HGILPCMVLAFQNVSVYMRYIRSSTIQQLEEDYVQIQYAYGASKKTVLYNHVLRNVLIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCHHHHHHHHHHHHHHHH
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ADILYGVVDPRIRMRG
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]