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The map label for this gene is lcoS [H]

Identifier: 118476336

GI number: 118476336

Start: 687117

End: 688508

Strand: Reverse

Name: lcoS [H]

Synonym: BALH_0592

Alternate gene names: 118476336

Gene position: 688508-687117 (Counterclockwise)

Preceding gene: 118476337

Following gene: 118476334

Centisome position: 13.1

GC content: 34.99

Gene sequence:

>1392_bases
ATGAAGCGAATTTCTATTCAACTCGGATTTTATTTTTTAATTGTTACACTTTTAATTGAAAGTGTTCTATTTGTCTTGCT
TTATTATAGCCTTGTCAACAATAGAGTAAATGAAGAAATGACAGCTTTATTAAAGCGCGGAAATAGTCATCGGGATGTCC
TTGAAAAGTATTTTGATAAGCAAACAATCTCCCATGTTGCACTAATGGAATCCGAAGCCGAAACGACTGTCGTTATTACA
AATGCAAATAAGGATGTGCTAGCTAAATCCAATGAAATAAATACTATTATAAAAAAGCATATTGAAAAGATGCAAACACG
GACAGATCACGACGGAGCAATTATAGAGAATCATTGGAAAACATCTAATTATATATGTACAGTTAGCCCCATTGTAGTAG
ATGGAAAACATGAAGGCTATGTGTACATGTTTCTTGGGACAGAATCTATTGAAAAAATGGTGAACGGGCTAACAAGACAA
TTCATTATTGCCGGCGTCATTACGTTTCTATTAACAGCCATCACTATCTTTCTCTTATCACGGTTGTTAACAAAACCATT
GTTACACATGAAACATGCCACTGAAAAAATGAGTAAAGGCGATTTATCAGTTTCGTTAACGACTACTCGAAATGATGAAA
TTGGTGAACTAGCATCATCTATTCAAACGCTTGCTAATGATTTACATTATATGAAAACAGAGCGAAGTGAATTTCTAGCA
AGTGTTGCTCACGAATTACGAACGCCGTTAACATACGTAAGAGGTTATGCTGACATTGCTTTAAAAGAAACCACATCTCC
TGAGCAACGTTTGCGATATTTATCTATTATAAAAGATGAGTCTGATTACATTACAAACTTAGTTCAAGATTTATTTTCAC
TGGCACAAATGGAACAACATAACTTTTCTATTCAAGTAAAGGAAGTACATTTACACACTTTCCTTACTCGCATATCTGAA
AAAGTAAACGCCATGTATAAAGAAAGATACATTACAGTTTCTTTCTCTTGTCCTCCTACACTGCTAGTAAACTTAGATGA
ACAACGATTTGAACAAGTTGTAGTGAACATTTTAAATAACGCTTATAGACATTCAAAAGAACATTCTCAAATTCATATTT
CTGTTATAGAAGAAAATAAACGTATCTCCATTACAATGGAAGATGAAGGCCAAGGTATTCCTCCTGAAGACCTCCCTCAC
ATTTTCGAACGCTTTTATCGAGTTGATAAAGCTAGATCACGAGCTACCGGTGGGACTGGTTTAGGGCTATCTATCGTGAA
AGAAATTGTAGAACTACACGGCGGAACTATTACTGTAACGAGCGAAGTTGATCACGGGTCTTGTTTTACAATTTCATTGC
CATCTATAAAGAAACACGACTACCATCAGTAG

Upstream 100 bases:

>100_bases
ATAAATTACGAAAAGTAAATTTCCCTATTGATCACCACTTAAAAACAGTTTACGGAGTCGGGTATCGATGGGTTGATACT
CTAGAGTAAGGAGCAAAACG

Downstream 100 bases:

>100_bases
TCGTGTTTCTTTATCATTTTACTTTATAATATAAGTTTACAAATTGCCCAAAACGTTTCGTATCCGTTAAAGTTAAATGG
ATTTCTGGGTTCTTGTCTTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDKQTISHVALMESEAETTVVIT
NANKDVLAKSNEINTIIKKHIEKMQTRTDHDGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTRQ
FIIAGVITFLLTAITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGQGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGTITVTSEVDHGSCFTISLPSIKKHDYHQ

Sequences:

>Translated_463_residues
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDKQTISHVALMESEAETTVVIT
NANKDVLAKSNEINTIIKKHIEKMQTRTDHDGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTRQ
FIIAGVITFLLTAITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGQGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGTITVTSEVDHGSCFTISLPSIKKHDYHQ
>Mature_463_residues
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDKQTISHVALMESEAETTVVIT
NANKDVLAKSNEINTIIKKHIEKMQTRTDHDGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTRQ
FIIAGVITFLLTAITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGQGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGTITVTSEVDHGSCFTISLPSIKKHDYHQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=31.7689530685921, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=32.046332046332, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786783, Length=348, Percent_Identity=27.8735632183908, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787894, Length=286, Percent_Identity=27.2727272727273, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790346, Length=338, Percent_Identity=28.9940828402367, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=30.8300395256917, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788713, Length=286, Percent_Identity=25.8741258741259, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=27.8008298755187, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=29.957805907173, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=31.0185185185185, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=28.1456953642384, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=25.297619047619, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=222, Percent_Identity=29.2792792792793, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082128, Length=308, Percent_Identity=24.3506493506494, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790861, Length=256, Percent_Identity=27.734375, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=29.7777777777778, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789808, Length=291, Percent_Identity=28.1786941580756, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789403, Length=334, Percent_Identity=27.5449101796407, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790551, Length=280, Percent_Identity=28.2142857142857, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=29.5275590551181, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=243, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52847; Mature: 52847

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDK
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNANKDVLAKSNEINTIIKKHIEKMQTRTDHDGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTRQFIIAGVITFLLTAITIFLLS
CCCEEEEECEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRISEKVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSQIHISVIEENKRISITMEDEGQGIPPEDLPHIFERFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
LGLSIVKEIVELHGGTITVTSEVDHGSCFTISLPSIKKHDYHQ
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKRISIQLGFYFLIVTLLIESVLFVLLYYSLVNNRVNEEMTALLKRGNSHRDVLEKYFDK
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNANKDVLAKSNEINTIIKKHIEKMQTRTDHDGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIVVDGKHEGYVYMFLGTESIEKMVNGLTRQFIIAGVITFLLTAITIFLLS
CCCEEEEECEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRISEKVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSQIHISVIEENKRISITMEDEGQGIPPEDLPHIFERFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
LGLSIVKEIVELHGGTITVTSEVDHGSCFTISLPSIKKHDYHQ
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]