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The map label for this gene is yabD [H]

Identifier: 118475811

GI number: 118475811

Start: 43755

End: 44522

Strand: Direct

Name: yabD [H]

Synonym: BALH_0035

Alternate gene names: 118475811

Gene position: 43755-44522 (Clockwise)

Preceding gene: 118475810

Following gene: 118475812

Centisome position: 0.83

GC content: 37.5

Gene sequence:

>768_bases
ATGTTGTTTGATACACATTCACATTTGAATGCAGAGCAATTTGAAGAAGACTTGCAAGAAGTTATTGCCCGAATGAAAGA
AGCGGGGGTTACTTATACAGTTGTTGTTGGTTTTGATGAAGCAACGATAAAAAAGGCGATTGAATTAGCTGAAGCCTATG
ATTTTATTTACGCTGCGATTGGATGGCATCCAGTTGATGCAATCGACATGACAGAAGAGCATTTAGCTTGGTTAGAAGAA
CTTGCTTCTCATCCTAAGGTCGTTGCACTTGGAGAAATGGGCTTAGATTATCACTGGGATAAGTCGCCAAAAGAAATACA
GAAAGAAGTATTCCGTAAACAAATTACGTTAGCGAAAAAGGTAAAGTTGCCGATTATTATACATAACCGCGATGCAACGC
AAGATATTGTTGATATTCTAGAAGAAGAGAATGCAGCTGAAGTAGGAGGCATTATGCATTGCTTTAGCGGCAGTGTAGAA
GTAGCAGAGCGATGTGTTGATATGAACTTTTTAATTTCATTAGGTGGACCAGTTACATTTAAAAACGCTAAGAAGCCGAA
AGAAGTTGCTACGGAGATTCCATTAGAGAAATTGTTAATAGAGACCGATTGTCCGTATTTAACACCACATCCATTTCGAG
GAAAACGAAATGAACCGAGTTATGTAAAACTCGTAGCAGAAGAAATTGCGAACTTAAAAGGAATTTCTTATGAAGAAGTA
GCGGAAATAACAACAAAAAATGCAAAGGCTTTATTTGGTGTTGAATAA

Upstream 100 bases:

>100_bases
TCATTTTTGCATTAAGATTGTAGTATTGTTATCGTTAAGTTATAAAAGAGCTTATTTGCGTAGAATAAATTTGATTTCAA
TATAAAAGGAGTTATGTATT

Downstream 100 bases:

>100_bases
AAGAGTGGGAGGACCCATTCTTTTTTTATTTTTGTGAAAAAATAGCAGGAGTGACAGAAAAGATAAGAGTGAATGAGTAG
ATGTTACAATAAGGAGAGAG

Product: TatD family deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLFDTHSHLNAEQFEEDLQEVIARMKEAGVTYTVVVGFDEATIKKAIELAEAYDFIYAAIGWHPVDAIDMTEEHLAWLEE
LASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQITLAKKVKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVE
VAERCVDMNFLISLGGPVTFKNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
AEITTKNAKALFGVE

Sequences:

>Translated_255_residues
MLFDTHSHLNAEQFEEDLQEVIARMKEAGVTYTVVVGFDEATIKKAIELAEAYDFIYAAIGWHPVDAIDMTEEHLAWLEE
LASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQITLAKKVKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVE
VAERCVDMNFLISLGGPVTFKNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
AEITTKNAKALFGVE
>Mature_255_residues
MLFDTHSHLNAEQFEEDLQEVIARMKEAGVTYTVVVGFDEATIKKAIELAEAYDFIYAAIGWHPVDAIDMTEEHLAWLEE
LASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQITLAKKVKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVE
VAERCVDMNFLISLGGPVTFKNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
AEITTKNAKALFGVE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=33.7121212121212, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=33.7121212121212, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI226061614, Length=253, Percent_Identity=33.596837944664, Blast_Score=131, Evalue=5e-31,
Organism=Homo sapiens, GI14042943, Length=270, Percent_Identity=29.2592592592593, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI225903424, Length=160, Percent_Identity=35, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=29.9559471365639, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI225903439, Length=248, Percent_Identity=28.2258064516129, Blast_Score=98, Evalue=6e-21,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=186, Evalue=9e-49,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=34.3511450381679, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=33.976833976834, Blast_Score=142, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=35.2313167259786, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=27.9693486590038, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17543026, Length=183, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=33.4821428571429, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=32.9824561403509, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24586117, Length=284, Percent_Identity=28.5211267605634, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221330018, Length=284, Percent_Identity=28.5211267605634, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28651; Mature: 28651

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDTHSHLNAEQFEEDLQEVIARMKEAGVTYTVVVGFDEATIKKAIELAEAYDFIYAAI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GWHPVDAIDMTEEHLAWLEELASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQITLAKK
CCCCCCHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVEVAERCVDMNFLISLGGPVTF
CCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCHHHEEECCCCEEE
KNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
CCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AEITTKNAKALFGVE
HHHHHCCCCEEECCC
>Mature Secondary Structure
MLFDTHSHLNAEQFEEDLQEVIARMKEAGVTYTVVVGFDEATIKKAIELAEAYDFIYAAI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GWHPVDAIDMTEEHLAWLEELASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQITLAKK
CCCCCCHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVEVAERCVDMNFLISLGGPVTF
CCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCHHHEEECCCCEEE
KNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
CCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AEITTKNAKALFGVE
HHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]