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The map label for this gene is dgk [H]

Identifier: 118475793

GI number: 118475793

Start: 23134

End: 23787

Strand: Reverse

Name: dgk [H]

Synonym: BALH_0016

Alternate gene names: 118475793

Gene position: 23787-23134 (Counterclockwise)

Preceding gene: 118475794

Following gene: 118475792

Centisome position: 0.45

GC content: 35.63

Gene sequence:

>654_bases
TTGAAAGGAGGAAACAGCGTGACCGGAGTACCATTTATCACGGTTGAAGGACCAATTGGTGTTGGAAAGACTTCACTTGC
GAAGGAAATTTCAACTCACATGCAACTCCACTTACTGAAAGAGATTGTTGATGAAAACCCCTTTTTAGGAAAGTTCTATG
AAGACATCGACGAATGGAGTTTTCAAACAGAGATGTTCTTTCTTTGTAATAGATACAAACAATTAGAAGATATTAACATA
AAGTATTTGAATCAAAGGAAGCCAGTAGTAGCGGATTATCACATATTCAAAAATGTAATTTTCGCATCCCGTACATTAAA
AGATTCTCAATATGACAAGTACATGCAAATCTATCGTATCCTTACACAAGATATGCCAGTGCCAAATGTTATCGTTTATT
TAACAGCTAGCTTAGAAACATTACAAAGGCGAATCGCCATGCGCGGAAGAGAATTCGAAAAAAATATGGATCCAAATTAC
TTACTACAGCTCACAAAAGATTACGAAACAGCAATGGATGCTTTTAAAAAGGACCATCCAGATATCCCAGTATTGAAATT
TAACGGAGACGATATGGATTTTGTAAAAAATCCTGATGATTTAAACGTCATCCTATCTGCCCTTCAAAATACTCTCTTAA
AGGAGTCGAAATAA

Upstream 100 bases:

>100_bases
ATCTATTTTCTAACTTTTTATATCAAATTAACCCGCTCGCTTCCCTCTTGTGCTACAATGATTCTGTTTTGTGTTTTTAG
TAGTCACGGTAAATCACTGA

Downstream 100 bases:

>100_bases
TAATGAATTTAAGGCAAAAATATGATATACCAAATGACGCAGTAATCACTATCGCTGGAACAGTAGGTGTCGGTAAATCC
ACTATGACAACTGCATTAGC

Product: deoxyguanosine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKGGNSVTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINI
KYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLETLQRRIAMRGREFEKNMDPNY
LLQLTKDYETAMDAFKKDHPDIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK

Sequences:

>Translated_217_residues
MKGGNSVTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINI
KYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLETLQRRIAMRGREFEKNMDPNY
LLQLTKDYETAMDAFKKDHPDIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK
>Mature_217_residues
MKGGNSVTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINI
KYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLETLQRRIAMRGREFEKNMDPNY
LLQLTKDYETAMDAFKKDHPDIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25259; Mature: 25259

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGGNSVTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWS
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FQTEMFFLCNRYKQLEDINIKYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRI
HHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LTQDMPVPNVIVYLTASLETLQRRIAMRGREFEKNMDPNYLLQLTKDYETAMDAFKKDHP
HHHCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHCCCCHHHEEEEHHHHHHHHHHHHCCCC
DIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGGNSVTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWS
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FQTEMFFLCNRYKQLEDINIKYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRI
HHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LTQDMPVPNVIVYLTASLETLQRRIAMRGREFEKNMDPNYLLQLTKDYETAMDAFKKDHP
HHHCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHCCCCHHHEEEEHHHHHHHHHHHHCCCC
DIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]