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The map label for this gene is hlyB [H]

Identifier: 117921928

GI number: 117921928

Start: 4186284

End: 4187948

Strand: Direct

Name: hlyB [H]

Synonym: Shewana3_3491

Alternate gene names: 117921928

Gene position: 4186284-4187948 (Clockwise)

Preceding gene: 117921925

Following gene: 117921930

Centisome position: 84.19

GC content: 50.69

Gene sequence:

>1665_bases
ATGTCTAATTTCAGTTTACGTAACAAATTGCTCCTACTCGCATTGTTCCCGTTAATTCTGACCTTCATTGTACTGATGAC
AGTTTCCTACCATGTCGAGCAATCGGCGCTTGCCGATGAGGTCACCACATTTAGAGAAAAGTTAATCGGTGAGCGTAAAA
CCCAAATCAAAGAAGCCACCCAAATCGCCGCAGGCATAGTGCAATACCAACTATCGTTAAAAGAACAGGGCAATGTTAAC
CAAGCCCTACGTGATATTCGCTTTGGCAGTTCGGGCTACTTCTTTCTTTATGATTCTCAAGGTAAAAACCTGTTCCATGC
GGTCATGCCCAACCTCGAGGGGCAGAATAAAATCGATATGACCGATCCCCGCGGCACCAAGATCATTGTCGGCCTGCTGA
ATGCCGCGAAAAACGGTGACGGTAATTTCTCGTTCTATTTCCAAAAACCCAATACCAACGAGCAAATCGAAAAAATCGGC
TACTCCATGATGATCCCAGGCACAGATTGGATGCTCGGCACTGGCGCCTATATCGACGATATCGATGCCGTGGTTGAGGA
TTACCGCACCACAGTCACCGAGCAGATGATCGATAAGTCCTACGCGATTTTATTGATTGCACTGTTATTAGCAGCCATTA
CCGCCCCCGTGATCTTAGTGACCGCCCAGCGCATGGTCACACCGATTAAAAACATGGCCGATAACTTAAACGATATCGCC
AAAGGCGAAGGCGATTTAACCAAGCGCCTCGCGGTGAAGGGCGACGATGAAATAGCTCAACTTGGCCGCTCCTTCAACCT
GTTTGTCGATAAACTGCAAACCATTATCGGCGATGTGGCCCATGCCACCGCTAAGGTTAAAACCGCAGCCAATGCGATTC
ATGACCAAACTAAAGTGATGTCGCGCCAGCTTATCAGCCATAACAATGAGACAGATCAAGTGGTGACCGCCATTACTGAG
ATGTCTGCCACCGCGAGTGAAGTGGCGCAAAATACCACCCAAGTGGCCGAAGCGACCCACGCCGCCACGGGCGATGTGGC
CAATGCCCAGCGCTGTGTCGATGCCTCGTTAGAGGAGATTTCGGCGCTGATGGCGCAAATCAATAATGCCGCCAGCAATA
TTCAATCCTTGAGTGAACAGTCGCAAAAAATTAATAGCGTGCTCTCGGTGATCGGCGGCATTGCCGAGCAAACCAACCTG
CTGGCATTAAATGCCGCGATTGAAGCCGCCCGCGCTGGCGAGCAGGGTCGCGGCTTTGCCGTGGTGGCCGATGAGGTGCG
TAACTTAGCCAGCCGCACTCAATCAAGCACATTAGAAATCAACGAGATGCTATCTGAGCTGCACAAGCTGGTTAGCTTAG
CGGTTAAAACCATGGAAGAGAGTCAGCAGAGCTGTATACGCTCGGTGGATTCGTCCCGCGCCATCTCCGAAAGCTTAGGC
TCAGTGACCTCGGCAGTAACCGCCATCAACGATATGAGTACCCAAATTGCCACGGCGGCGACCGAGCAAAGCTCAGTGAC
CGAAGAAATCAACCGCAATGTGTTTGCCATTCAAGAGATTGTGAATGAGCTGCTGCACTCAAGCGAAGAGGCGGCGAGCG
TGAGCCAAACCGTGTCGCAGGAAGGACTTAACCTCGGCAAACTCGTGGGCCAATTTAAGATTTAA

Upstream 100 bases:

>100_bases
CGGTTACATTAGATTTTTGTTAACTTAAGCACTTAAGAGTATTGGGGATTCGTTATACTGCCCTGCAATAATAAAGCGGC
TTATCCCGGAGTTGTTGAAC

Downstream 100 bases:

>100_bases
TGCCTAAGGCGTGATATTGGCGTAAGTCGATCAAATGTTAATCGATTCAGTGTTAGTCGATTCTGTATAAATCACTATCT
TTAACCACCTAAGGCCTCAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSNFSLRNKLLLLALFPLILTFIVLMTVSYHVEQSALADEVTTFREKLIGERKTQIKEATQIAAGIVQYQLSLKEQGNVN
QALRDIRFGSSGYFFLYDSQGKNLFHAVMPNLEGQNKIDMTDPRGTKIIVGLLNAAKNGDGNFSFYFQKPNTNEQIEKIG
YSMMIPGTDWMLGTGAYIDDIDAVVEDYRTTVTEQMIDKSYAILLIALLLAAITAPVILVTAQRMVTPIKNMADNLNDIA
KGEGDLTKRLAVKGDDEIAQLGRSFNLFVDKLQTIIGDVAHATAKVKTAANAIHDQTKVMSRQLISHNNETDQVVTAITE
MSATASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEISALMAQINNAASNIQSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSTLEINEMLSELHKLVSLAVKTMEESQQSCIRSVDSSRAISESLG
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVFAIQEIVNELLHSSEEAASVSQTVSQEGLNLGKLVGQFKI

Sequences:

>Translated_554_residues
MSNFSLRNKLLLLALFPLILTFIVLMTVSYHVEQSALADEVTTFREKLIGERKTQIKEATQIAAGIVQYQLSLKEQGNVN
QALRDIRFGSSGYFFLYDSQGKNLFHAVMPNLEGQNKIDMTDPRGTKIIVGLLNAAKNGDGNFSFYFQKPNTNEQIEKIG
YSMMIPGTDWMLGTGAYIDDIDAVVEDYRTTVTEQMIDKSYAILLIALLLAAITAPVILVTAQRMVTPIKNMADNLNDIA
KGEGDLTKRLAVKGDDEIAQLGRSFNLFVDKLQTIIGDVAHATAKVKTAANAIHDQTKVMSRQLISHNNETDQVVTAITE
MSATASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEISALMAQINNAASNIQSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSTLEINEMLSELHKLVSLAVKTMEESQQSCIRSVDSSRAISESLG
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVFAIQEIVNELLHSSEEAASVSQTVSQEGLNLGKLVGQFKI
>Mature_553_residues
SNFSLRNKLLLLALFPLILTFIVLMTVSYHVEQSALADEVTTFREKLIGERKTQIKEATQIAAGIVQYQLSLKEQGNVNQ
ALRDIRFGSSGYFFLYDSQGKNLFHAVMPNLEGQNKIDMTDPRGTKIIVGLLNAAKNGDGNFSFYFQKPNTNEQIEKIGY
SMMIPGTDWMLGTGAYIDDIDAVVEDYRTTVTEQMIDKSYAILLIALLLAAITAPVILVTAQRMVTPIKNMADNLNDIAK
GEGDLTKRLAVKGDDEIAQLGRSFNLFVDKLQTIIGDVAHATAKVKTAANAIHDQTKVMSRQLISHNNETDQVVTAITEM
SATASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEISALMAQINNAASNIQSLSEQSQKINSVLSVIGGIAEQTNLL
ALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSTLEINEMLSELHKLVSLAVKTMEESQQSCIRSVDSSRAISESLGS
VTSAVTAINDMSTQIATAATEQSSVTEEINRNVFAIQEIVNELLHSSEEAASVSQTVSQEGLNLGKLVGQFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=329, Percent_Identity=30.0911854103343, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788194, Length=363, Percent_Identity=29.4765840220386, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788195, Length=298, Percent_Identity=30.5369127516779, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1787690, Length=387, Percent_Identity=25.5813953488372, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789453, Length=357, Percent_Identity=27.7310924369748, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59942; Mature: 59811

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFSLRNKLLLLALFPLILTFIVLMTVSYHVEQSALADEVTTFREKLIGERKTQIKEAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIAAGIVQYQLSLKEQGNVNQALRDIRFGSSGYFFLYDSQGKNLFHAVMPNLEGQNKIDM
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCC
TDPRGTKIIVGLLNAAKNGDGNFSFYFQKPNTNEQIEKIGYSMMIPGTDWMLGTGAYIDD
CCCCCCEEEEEHHHHCCCCCCCEEEEEECCCCHHHHHHCCCEEECCCCCCEEECCCHHHH
IDAVVEDYRTTVTEQMIDKSYAILLIALLLAAITAPVILVTAQRMVTPIKNMADNLNDIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGEGDLTKRLAVKGDDEIAQLGRSFNLFVDKLQTIIGDVAHATAKVKTAANAIHDQTKVM
CCCCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQLISHNNETDQVVTAITEMSATASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SALMAQINNAASNIQSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQSSTLEINEMLSELHKLVSLAVKTMEESQQSCIRSVDSSRAISESLG
EEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVFAIQEIVNELLHSSEEAASVSQTVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
EGLNLGKLVGQFKI
HCCCHHHHHHHCCC
>Mature Secondary Structure 
SNFSLRNKLLLLALFPLILTFIVLMTVSYHVEQSALADEVTTFREKLIGERKTQIKEAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIAAGIVQYQLSLKEQGNVNQALRDIRFGSSGYFFLYDSQGKNLFHAVMPNLEGQNKIDM
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCC
TDPRGTKIIVGLLNAAKNGDGNFSFYFQKPNTNEQIEKIGYSMMIPGTDWMLGTGAYIDD
CCCCCCEEEEEHHHHCCCCCCCEEEEEECCCCHHHHHHCCCEEECCCCCCEEECCCHHHH
IDAVVEDYRTTVTEQMIDKSYAILLIALLLAAITAPVILVTAQRMVTPIKNMADNLNDIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGEGDLTKRLAVKGDDEIAQLGRSFNLFVDKLQTIIGDVAHATAKVKTAANAIHDQTKVM
CCCCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQLISHNNETDQVVTAITEMSATASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SALMAQINNAASNIQSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQSSTLEINEMLSELHKLVSLAVKTMEESQQSCIRSVDSSRAISESLG
EEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVFAIQEIVNELLHSSEEAASVSQTVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
EGLNLGKLVGQFKI
HCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]