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The map label for this gene is tkt1 [H]

Identifier: 117921791

GI number: 117921791

Start: 4022623

End: 4024617

Strand: Reverse

Name: tkt1 [H]

Synonym: Shewana3_3353

Alternate gene names: 117921791

Gene position: 4024617-4022623 (Counterclockwise)

Preceding gene: 117921794

Following gene: 117921790

Centisome position: 80.94

GC content: 50.68

Gene sequence:

>1995_bases
ATGTCTTCCCGTAAAGTACTCGCCAACGCAATCCGTGCGTTAAGTATGGATGCAGTTCAAAAAGCAAACTCAGGCCACCC
TGGCGCCCCTATGGGCATGGCAGATATTGCTGAAGTGCTGTGGAATGATTTCCTTAAGCACAATCCGAACAATCCGAAAT
GGGTAGATAGAGATCGTTTTATCCTCTCTAACGGTCACGGATCTATGCTGATCTACTCTTTATTACACCTGACTGGCTAC
GACCTGCCTATCGATGAACTGAAGCAATTCCGTCAGTTACATTCAAAAACTCCGGGTCACCCAGAATACGGCTACACCCC
TGGTGTTGAAACCACCACTGGCCCATTAGGGGCGGGGATCAGCAACGCTGTGGGTATGGCGATTGCAGAAAAAACCTTAG
CGGCACAGTTCAACCGTGAAGGTCACGAGATTGTTGACCACTACACATACTGCTTCCTCGGCGATGGCTGCTTGATGGAA
GGTATTTCCCACGAAGCTTGTTCTCTGGCTGGTACCTTAGGCCTAGGCAAACTGATCGCATTTTGGGATGACAATGGCAT
CTCTATCGACGGTCATGTTGAAGGCTGGTTTACCGATGACACGCCAAAACGTTTCGAATCATACGGCTGGCATGTAATTG
CTAACGTTGATGGTCACGATAGCGATGCGATTCGCGCGGCTATCGAAGCGGCAAAAGCCGTGACCGACAAGCCAACCATG
ATCTGCTGCAAAACCATTATCGGTTTTGGTTCACCAAACAAATCTGGCAGCCACGATTGCCACGGCGCGCCATTAGGTGA
TGCAGAAATCGCCGCGGCCCGTGAATTCTTAGGCTGGCCACATGCGCCATTCGAAATCCCTGCCGACGTATACGCAGGTT
GGGATGCTAAAGAAGCCGGTAACGCCCGTGAAGCGGCTTGGAACGACAAGTTTGCCGCTTACGCTGCTGCTTACCCAGAA
CTGGCTGCCGAATACGAGCGCCGTGTGCTGAAAGGTGAATTACCAGCCGATTTCGAAGCTAAAGCGCAAGCTTTTATCCA
AGAATGCCAAGCGAAAGGCGAAGGTATTGCGAGCCGTAAAGCGTCACAAAACGCGATTGCAGCCTTCGGTGCGGTTCTGC
CTGAACTGTTAGGCGGCAGTGCTGACTTAGCGGGTTCTAACCTGACCTTGTGGGCAGGTTCTAGAGGTATTCAAGAAGAT
CCAGCGGGTAACTACGTGTACTACGGTGTGCGTGAGTTTGGTATGAGCGGCATCATGAACGGTGTGTCACTCCACGGTGG
TTTCATCAACTACGGCGCGACTTTCATGATGTTCATGGAATACGCACGTAACGCAGTACGTATGTCTGCGCTGATGGGCA
TTCAAAACATCTTCGTTTACACCCATGACTCTATCGGTCAAGGTGAAGATGGTCCAACTCACCAACCCGTTGAGCAATTA
GCTAACCTGCGCATGACACCAAACATGGCGGTATGGCGCCCATGTGACGCGGCTGAAACCGCAGTGGCTTGGAAAGCGGC
TATCGAACGTCGTCATGCACCAACATCGCTAGTATTCAGCCGTCAAAACCTGAAGGCTCAAGCACGTACAGCTGAGCAAT
TAGCGAATGTGGCAAAAGGCGCTTATGTACTGCAAGACTGTGCAGGTACGCCTGAGTACATCCTGATTGCAACCGGTAGT
GAAGTGCAATTAGCGGTAGAAGCGGCGGCTGCGCTGACTGAACAAGGCAAACAAATTCGCGTTGTTTCTATGCCATCAAA
CACTGAGTTTGATAAGCAAGATGCCGCATACAAAGAGTCTGTACTGCCAAAAGCTGTGACTAAGCGTATTGCTATCGAAG
CGGCCCATACTGACTTCTGGTACAAGTATGTTGGTTTCGAAGGCACTGTTGTTGGCATGACCACTTTTGGTGAGTCTGCG
CCAGGTAACGTGCTGCTGAAGCACTTCGGTTTCACCGTTGAAAATGTGCTGAATGCTGCAAAATCACTAGGCTAA

Upstream 100 bases:

>100_bases
GGACAGTGGAATGCAATTTTCGTTTGCGTCGCTTCGCTATGTAGGGGAAAATATGCGTCCAAATTGCCCGCTAGACCCCA
CAAATTAAGCAGGAGAGAGC

Downstream 100 bases:

>100_bases
TCGCTTAGGTGATGAGATTACCGACAAAAGGTTAAACTTTTGAAAGGTTAATCTGTATAATGCGGCCTGCAATCGTTTGC
AGGCCGTTTTTGTATATGCA

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPNNPKWVDRDRFILSNGHGSMLIYSLLHLTGY
DLPIDELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGISNAVGMAIAEKTLAAQFNREGHEIVDHYTYCFLGDGCLME
GISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIANVDGHDSDAIRAAIEAAKAVTDKPTM
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPHAPFEIPADVYAGWDAKEAGNAREAAWNDKFAAYAAAYPE
LAAEYERRVLKGELPADFEAKAQAFIQECQAKGEGIASRKASQNAIAAFGAVLPELLGGSADLAGSNLTLWAGSRGIQED
PAGNYVYYGVREFGMSGIMNGVSLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
ANLRMTPNMAVWRPCDAAETAVAWKAAIERRHAPTSLVFSRQNLKAQARTAEQLANVAKGAYVLQDCAGTPEYILIATGS
EVQLAVEAAAALTEQGKQIRVVSMPSNTEFDKQDAAYKESVLPKAVTKRIAIEAAHTDFWYKYVGFEGTVVGMTTFGESA
PGNVLLKHFGFTVENVLNAAKSLG

Sequences:

>Translated_664_residues
MSSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPNNPKWVDRDRFILSNGHGSMLIYSLLHLTGY
DLPIDELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGISNAVGMAIAEKTLAAQFNREGHEIVDHYTYCFLGDGCLME
GISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIANVDGHDSDAIRAAIEAAKAVTDKPTM
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPHAPFEIPADVYAGWDAKEAGNAREAAWNDKFAAYAAAYPE
LAAEYERRVLKGELPADFEAKAQAFIQECQAKGEGIASRKASQNAIAAFGAVLPELLGGSADLAGSNLTLWAGSRGIQED
PAGNYVYYGVREFGMSGIMNGVSLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
ANLRMTPNMAVWRPCDAAETAVAWKAAIERRHAPTSLVFSRQNLKAQARTAEQLANVAKGAYVLQDCAGTPEYILIATGS
EVQLAVEAAAALTEQGKQIRVVSMPSNTEFDKQDAAYKESVLPKAVTKRIAIEAAHTDFWYKYVGFEGTVVGMTTFGESA
PGNVLLKHFGFTVENVLNAAKSLG
>Mature_663_residues
SSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPNNPKWVDRDRFILSNGHGSMLIYSLLHLTGYD
LPIDELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGISNAVGMAIAEKTLAAQFNREGHEIVDHYTYCFLGDGCLMEG
ISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIANVDGHDSDAIRAAIEAAKAVTDKPTMI
CCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPHAPFEIPADVYAGWDAKEAGNAREAAWNDKFAAYAAAYPEL
AAEYERRVLKGELPADFEAKAQAFIQECQAKGEGIASRKASQNAIAAFGAVLPELLGGSADLAGSNLTLWAGSRGIQEDP
AGNYVYYGVREFGMSGIMNGVSLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQLA
NLRMTPNMAVWRPCDAAETAVAWKAAIERRHAPTSLVFSRQNLKAQARTAEQLANVAKGAYVLQDCAGTPEYILIATGSE
VQLAVEAAAALTEQGKQIRVVSMPSNTEFDKQDAAYKESVLPKAVTKRIAIEAAHTDFWYKYVGFEGTVVGMTTFGESAP
GNVLLKHFGFTVENVLNAAKSLG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=580, Percent_Identity=25.5172413793103, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI205277463, Length=268, Percent_Identity=33.2089552238806, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4507521, Length=268, Percent_Identity=33.2089552238806, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI225637459, Length=597, Percent_Identity=22.2780569514238, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI225637463, Length=502, Percent_Identity=23.3067729083665, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI225637461, Length=502, Percent_Identity=23.3067729083665, Blast_Score=92, Evalue=2e-18,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=74.5098039215686, Blast_Score=1062, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=663, Percent_Identity=66.5158371040724, Blast_Score=955, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=680, Percent_Identity=24.2647058823529, Blast_Score=149, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6325331, Length=668, Percent_Identity=48.6526946107784, Blast_Score=588, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6319593, Length=670, Percent_Identity=45.6716417910448, Blast_Score=548, Evalue=1e-156,
Organism=Drosophila melanogaster, GI45551847, Length=681, Percent_Identity=25.8443465491924, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI45550715, Length=681, Percent_Identity=25.8443465491924, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24666278, Length=685, Percent_Identity=24.0875912408759, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24645119, Length=647, Percent_Identity=25.193199381762, Blast_Score=138, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71566; Mature: 71435

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPNNPKWVDRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCEE
ILSNGHGSMLIYSLLHLTGYDLPIDELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
SNAVGMAIAEKTLAAQFNREGHEIVDHYTYCFLGDGCLMEGISHEACSLAGTLGLGKLIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHHHCCCCEEE
FWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIANVDGHDSDAIRAAIEAAKAVTDKPTM
EECCCCEEECCCCCEEECCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHH
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPHAPFEIPADVYAGWDAKEAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCC
NAREAAWNDKFAAYAAAYPELAAEYERRVLKGELPADFEAKAQAFIQECQAKGEGIASRK
CCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
ASQNAIAAFGAVLPELLGGSADLAGSNLTLWAGSRGIQEDPAGNYVYYGVREFGMSGIMN
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECHHHHCHHHHCC
GVSLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHH
ANLRMTPNMAVWRPCDAAETAVAWKAAIERRHAPTSLVFSRQNLKAQARTAEQLANVAKG
HCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHEEEHHHHHHHHHHHHHHHHHHHH
AYVLQDCAGTPEYILIATGSEVQLAVEAAAALTEQGKQIRVVSMPSNTEFDKQDAAYKES
HHHHHHCCCCCCEEEEEECCCEEHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHH
VLPKAVTKRIAIEAAHTDFWYKYVGFEGTVVGMTTFGESAPGNVLLKHFGFTVENVLNAA
HCHHHHHHHHHHEECCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHH
KSLG
HHCC
>Mature Secondary Structure 
SSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPNNPKWVDRDRF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCEE
ILSNGHGSMLIYSLLHLTGYDLPIDELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
SNAVGMAIAEKTLAAQFNREGHEIVDHYTYCFLGDGCLMEGISHEACSLAGTLGLGKLIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHHHCCCCEEE
FWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIANVDGHDSDAIRAAIEAAKAVTDKPTM
EECCCCEEECCCCCEEECCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHH
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPHAPFEIPADVYAGWDAKEAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCC
NAREAAWNDKFAAYAAAYPELAAEYERRVLKGELPADFEAKAQAFIQECQAKGEGIASRK
CCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
ASQNAIAAFGAVLPELLGGSADLAGSNLTLWAGSRGIQEDPAGNYVYYGVREFGMSGIMN
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECHHHHCHHHHCC
GVSLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHH
ANLRMTPNMAVWRPCDAAETAVAWKAAIERRHAPTSLVFSRQNLKAQARTAEQLANVAKG
HCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHEEEHHHHHHHHHHHHHHHHHHHH
AYVLQDCAGTPEYILIATGSEVQLAVEAAAALTEQGKQIRVVSMPSNTEFDKQDAAYKES
HHHHHHCCCCCCEEEEEECCCEEHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHH
VLPKAVTKRIAIEAAHTDFWYKYVGFEGTVVGMTTFGESAPGNVLLKHFGFTVENVLNAA
HCHHHHHHHHHHEECCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHH
KSLG
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]