Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 117921737

GI number: 117921737

Start: 3952386

End: 3954050

Strand: Reverse

Name: hlyB [H]

Synonym: Shewana3_3299

Alternate gene names: 117921737

Gene position: 3954050-3952386 (Counterclockwise)

Preceding gene: 117921738

Following gene: 117921735

Centisome position: 79.52

GC content: 49.13

Gene sequence:

>1665_bases
ATGTCGAATTTAAGCCTGCGTAATAAACTACTGCTGTTGTCTTTGTTCCCCCTAATCTTGACCTTATTAGTGCTGATGAC
CGTTTCCTACTACGTCGAGCAGGAATCTCTCGCGGAAGAAGTGGTGACCTTTAGAACGAAATTGGTGGGCGAACGTAAAC
AACAAATCAAAGAAGCGACCGAAATTGCTGCAGGGATTGTGCAATATCAACTGTCATTGAAAGACCAAGGCAATGTGAAC
CAAGCTCTGCGTGATATTCGTTTTGGCAGCGCGGGTTATTTCTTTATTTATGATTCCCAAGGCAAAAACATTTTCCACGC
CTTGATGCCTAATCTTGAAGGGCAAAACAAAATCGATATGACCGACCCTCGCGGTACTAAGATCATCGTTGGTTTGCTGG
ATGCGGCCAAACGTGGTGACGGTAACTTTTCCTATTACTATCAAAAGCCTAATACTAACGAGCAAATCGAGAAGATTAGC
TATGTGATGATGGTTCCAGGTACTGACTGGATGCTAGGTACAGGGGCTTATATCGACGATATCGAAGCCGTAGTCGAGGA
TTACCGCCAAACCGTAACCGAACAAATGGCCGATAAGTCCTTCATGATCCTATTAATCGCCCTCGTGCTGACGGGGATCA
CGGCCTTTATCATCATGGTCGCCGCCCATCGTATGGTGGTGCCGATTAAGAATATGGCGGATAGCCTGAATGATATCGCT
AAGGGTGAAGGTGACTTAACCAAACGCTTAAGCGTGAAGGGCGAGGATGAAATTGCTCAGTTAGGTCAAGCCTTTAACTT
GTTTGTCGATAAGCTGCAAACCATTATTGGCGATGTGGCAAACGCAACGGCTAAGGTGAAATCCGCCGCCAATGCGATTC
ACGATCAAACCAAAGTGATGTCGAGCCAGCTGCTGAGCCACAATAACGAGACAGACCAAGTGGTGACGGCTATTACCGAG
ATGTCGTCCACCGCGAGTGAAGTGGCGCAAAATACCACCCAAGTGGCCGAGGCGACCCAAGCGGCGACGGGTGATGTGGC
AAATGCCCAGCGCTGTGTCGATGCCTCGCTCGAAGAGATTGCTGGACTCATGTCGCAAATCAACAATGCTGCGGGCAGTA
TTAAATCCTTAAGTGAGCAATCGCAAAAAATTAACAGTGTGTTGTCTGTGATTGGCGGTATTGCCGAGCAAACTAACCTG
CTGGCCCTTAACGCTGCGATTGAAGCGGCCCGCGCCGGTGAACAGGGCCGTGGTTTTGCCGTGGTGGCCGACGAAGTGCG
TAATCTTGCCAGCCGTACTCAGGCAAGTACCTTAGAAATCAACGAAATGCTCTCTGAGCTGCATAAGTTAGTCTCGGTCG
CAGTTAAAACCATGGACGAGAGCCAGCAGAGCTGCGTGCGCTCGGTGGATTCTTCCCGCGCTATTTCCGAGAGCTTAGGC
TCTGTGACATCGGCGGTAACCGCGATTAATGATATGAGTACCCAGATTGCGACGGCGGCGACCGAGCAAAGCTCTGTGAC
CGAAGAAATTAATCGTAACGTTTATGCCATCCAAGAGATCGTTAACGAGCTGCTGCATTCCAGTGAAGATGCGGCCAAGG
TGAGTCAAACCGTGTCTCAGGAAGGGATTAACCTCGGTAAATTGGTGGGGCAGTTTAAGATTTAA

Upstream 100 bases:

>100_bases
TACGATATTTGTTAAGTTAAACGCAAAGATGTTGCACTGTTTTGGCTATACTTCAAAAATATAAAAAAATATAAGCTCGA
TCACCCTGGAGTAAGCAAGC

Downstream 100 bases:

>100_bases
CTCATCTAATTAAACAAGTTAATTAAATTCGCGAATGAAAAACGGGAGACATTGTCTCCCGTTTTTTATATCCAGCGATG
GGTCTATCCCTTGCAGGGGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSNLSLRNKLLLLSLFPLILTLLVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEATEIAAGIVQYQLSLKDQGNVN
QALRDIRFGSAGYFFIYDSQGKNIFHALMPNLEGQNKIDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKIS
YVMMVPGTDWMLGTGAYIDDIEAVVEDYRQTVTEQMADKSFMILLIALVLTGITAFIIMVAAHRMVVPIKNMADSLNDIA
KGEGDLTKRLSVKGEDEIAQLGQAFNLFVDKLQTIIGDVANATAKVKSAANAIHDQTKVMSSQLLSHNNETDQVVTAITE
MSSTASEVAQNTTQVAEATQAATGDVANAQRCVDASLEEIAGLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSELHKLVSVAVKTMDESQQSCVRSVDSSRAISESLG
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQEGINLGKLVGQFKI

Sequences:

>Translated_554_residues
MSNLSLRNKLLLLSLFPLILTLLVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEATEIAAGIVQYQLSLKDQGNVN
QALRDIRFGSAGYFFIYDSQGKNIFHALMPNLEGQNKIDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKIS
YVMMVPGTDWMLGTGAYIDDIEAVVEDYRQTVTEQMADKSFMILLIALVLTGITAFIIMVAAHRMVVPIKNMADSLNDIA
KGEGDLTKRLSVKGEDEIAQLGQAFNLFVDKLQTIIGDVANATAKVKSAANAIHDQTKVMSSQLLSHNNETDQVVTAITE
MSSTASEVAQNTTQVAEATQAATGDVANAQRCVDASLEEIAGLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSELHKLVSVAVKTMDESQQSCVRSVDSSRAISESLG
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQEGINLGKLVGQFKI
>Mature_553_residues
SNLSLRNKLLLLSLFPLILTLLVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEATEIAAGIVQYQLSLKDQGNVNQ
ALRDIRFGSAGYFFIYDSQGKNIFHALMPNLEGQNKIDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISY
VMMVPGTDWMLGTGAYIDDIEAVVEDYRQTVTEQMADKSFMILLIALVLTGITAFIIMVAAHRMVVPIKNMADSLNDIAK
GEGDLTKRLSVKGEDEIAQLGQAFNLFVDKLQTIIGDVANATAKVKSAANAIHDQTKVMSSQLLSHNNETDQVVTAITEM
SSTASEVAQNTTQVAEATQAATGDVANAQRCVDASLEEIAGLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLL
ALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSELHKLVSVAVKTMDESQQSCVRSVDSSRAISESLGS
VTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQEGINLGKLVGQFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=374, Percent_Identity=30.4812834224599, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=29.96632996633, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1787690, Length=391, Percent_Identity=26.5984654731458, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1788194, Length=368, Percent_Identity=27.7173913043478, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1789453, Length=352, Percent_Identity=27.5568181818182, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59937; Mature: 59806

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLSLRNKLLLLSLFPLILTLLVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAAGIVQYQLSLKDQGNVNQALRDIRFGSAGYFFIYDSQGKNIFHALMPNLEGQNKIDM
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCC
TDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISYVMMVPGTDWMLGTGAYIDD
CCCCCCEEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHEEEEECCCCCEEECCCHHHH
IEAVVEDYRQTVTEQMADKSFMILLIALVLTGITAFIIMVAAHRMVVPIKNMADSLNDIA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
KGEGDLTKRLSVKGEDEIAQLGQAFNLFVDKLQTIIGDVANATAKVKSAANAIHDQTKVM
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSQLLSHNNETDQVVTAITEMSSTASEVAQNTTQVAEATQAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AGLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQASTLEINEMLSELHKLVSVAVKTMDESQQSCVRSVDSSRAISESLG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
EGINLGKLVGQFKI
CCCCHHHHHHHCCC
>Mature Secondary Structure 
SNLSLRNKLLLLSLFPLILTLLVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAAGIVQYQLSLKDQGNVNQALRDIRFGSAGYFFIYDSQGKNIFHALMPNLEGQNKIDM
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCC
TDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISYVMMVPGTDWMLGTGAYIDD
CCCCCCEEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHEEEEECCCCCEEECCCHHHH
IEAVVEDYRQTVTEQMADKSFMILLIALVLTGITAFIIMVAAHRMVVPIKNMADSLNDIA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
KGEGDLTKRLSVKGEDEIAQLGQAFNLFVDKLQTIIGDVANATAKVKSAANAIHDQTKVM
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSQLLSHNNETDQVVTAITEMSSTASEVAQNTTQVAEATQAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AGLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQASTLEINEMLSELHKLVSVAVKTMDESQQSCVRSVDSSRAISESLG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
EGINLGKLVGQFKI
CCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]