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The map label for this gene is cobT [H]

Identifier: 117921716

GI number: 117921716

Start: 3917691

End: 3918743

Strand: Reverse

Name: cobT [H]

Synonym: Shewana3_3278

Alternate gene names: 117921716

Gene position: 3918743-3917691 (Counterclockwise)

Preceding gene: 117921717

Following gene: 117921715

Centisome position: 78.81

GC content: 52.99

Gene sequence:

>1053_bases
ATGCCTCAATCTGTCCCGTTATTTCAAATCGAGCCTGTGAGTAAAGCGCAGGATCAACTCATCCAGCAAAAGATCGATCT
TAAGACTAAGCCGCCCGGCGCTCTGGGGCAGTTAGAGTCCTTGGCGTTGCAAATTGCCCGCATCCAAGGGGCTAAGCAGT
TGCAGATTGTTTACCCGACTATGTTGGTGTTTGCCGGAGATCATGGGATTGCTGCCGAAGGGGTGTCGATTGCCCCGAGT
GAAGTCACGCGGCAGATGGTGCAAAACTTTGCCCATGGCGGCGCGGCCATCAATGTGTTTTGTCGTCAGTTAGGCTTCAA
TCTCGAAGTGATTGATTGTGGTATTTTAACCCCAGTTGAAGATGCCGAAGGCATTATCGACCAACGCCTTGGTGCGGGAA
CGGCCGCGATTCACTTAGAACCTGCCATGACGTTAGCCTGCGTGGATAAGGGCTTTGCCATGGCGCAGGCATTAATCGAG
CGTCACCATCAGGCGGGCTGTAACTTGGTTGCCTTTGGTGAGATGGGCATAGGTAATACTTCGTCAGCTGCGGCGATTAT
GGCGGCCATTATGCAACTCGATGTGGCCGACTGTGTTGGCCGTGGTACGGGCATCAATAGCGAGACCCTAGAGCGTAAAC
AGATGCTTATCGAACTCGCGCTGCTGTTACACCAGAGTGCGATGACAGGGCCTCGGCAAGTGCTGGCCTGTTTGGGCGGC
TTTGAAATTGTGCAGATGACGGGGGCCATGCTCGCCGCTGCCGAGCGCAAGATGCTGGTCGTGGTGGATGGTTTTATTGC
GACCGCAGCGGCTTTGGTTGCCGTGAGTATCAATGCGAATGTGCGGGATTATTTGATTTTTGCCCACCGCTCCGAGGAGC
AAGGTCATCAGCGCATGTTGGAACATTTAAAGGCTAAGCCCTTGTTATCTTTAGGGCTGCGATTAGGCGAAGGCACGGGC
GCTGCCTTGGCATTGCCGTTAATTCAAGCCGCTGTAAATTTTTACAATCAAATGGCGAGTTTTAGTGATGCGGGGATTGA
GGCTGTTGTATGA

Upstream 100 bases:

>100_bases
CTTCGTAGTTGTTGTTCTAGAATGTGTTAGCGAACGTACTCGCAAATGAGTTATTAGCAGCGGATCTATCATTGGATCCG
ACATTGCCACTGGAGTGTGA

Downstream 100 bases:

>100_bases
TGTGCGCTGCTAAGTGGCTTATTTAAAATAATAACTTTTAGCAGACCTTTTTAATCTTAAACCTTGCAGCAAGTGTTAAT
TCACTAAGGATGCTTTATGT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPQSVPLFQIEPVSKAQDQLIQQKIDLKTKPPGALGQLESLALQIARIQGAKQLQIVYPTMLVFAGDHGIAAEGVSIAPS
EVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVEDAEGIIDQRLGAGTAAIHLEPAMTLACVDKGFAMAQALIE
RHHQAGCNLVAFGEMGIGNTSSAAAIMAAIMQLDVADCVGRGTGINSETLERKQMLIELALLLHQSAMTGPRQVLACLGG
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVSINANVRDYLIFAHRSEEQGHQRMLEHLKAKPLLSLGLRLGEGTG
AALALPLIQAAVNFYNQMASFSDAGIEAVV

Sequences:

>Translated_350_residues
MPQSVPLFQIEPVSKAQDQLIQQKIDLKTKPPGALGQLESLALQIARIQGAKQLQIVYPTMLVFAGDHGIAAEGVSIAPS
EVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVEDAEGIIDQRLGAGTAAIHLEPAMTLACVDKGFAMAQALIE
RHHQAGCNLVAFGEMGIGNTSSAAAIMAAIMQLDVADCVGRGTGINSETLERKQMLIELALLLHQSAMTGPRQVLACLGG
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVSINANVRDYLIFAHRSEEQGHQRMLEHLKAKPLLSLGLRLGEGTG
AALALPLIQAAVNFYNQMASFSDAGIEAVV
>Mature_349_residues
PQSVPLFQIEPVSKAQDQLIQQKIDLKTKPPGALGQLESLALQIARIQGAKQLQIVYPTMLVFAGDHGIAAEGVSIAPSE
VTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVEDAEGIIDQRLGAGTAAIHLEPAMTLACVDKGFAMAQALIER
HHQAGCNLVAFGEMGIGNTSSAAAIMAAIMQLDVADCVGRGTGINSETLERKQMLIELALLLHQSAMTGPRQVLACLGGF
EIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVSINANVRDYLIFAHRSEEQGHQRMLEHLKAKPLLSLGLRLGEGTGA
ALALPLIQAAVNFYNQMASFSDAGIEAVV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=345, Percent_Identity=36.231884057971, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37011; Mature: 36880

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSVPLFQIEPVSKAQDQLIQQKIDLKTKPPGALGQLESLALQIARIQGAKQLQIVYPT
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEE
MLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCH
DAEGIIDQRLGAGTAAIHLEPAMTLACVDKGFAMAQALIERHHQAGCNLVAFGEMGIGNT
HHHHHHHHHCCCCEEEEEECCHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
SSAAAIMAAIMQLDVADCVGRGTGINSETLERKQMLIELALLLHQSAMTGPRQVLACLGG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVSINANVRDYLIFAHRSEEQGHQRML
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHEEECCCCEEEEEEEECCHHHHHHHHH
EHLKAKPLLSLGLRLGEGTGAALALPLIQAAVNFYNQMASFSDAGIEAVV
HHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECC
>Mature Secondary Structure 
PQSVPLFQIEPVSKAQDQLIQQKIDLKTKPPGALGQLESLALQIARIQGAKQLQIVYPT
CCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEE
MLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCH
DAEGIIDQRLGAGTAAIHLEPAMTLACVDKGFAMAQALIERHHQAGCNLVAFGEMGIGNT
HHHHHHHHHCCCCEEEEEECCHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
SSAAAIMAAIMQLDVADCVGRGTGINSETLERKQMLIELALLLHQSAMTGPRQVLACLGG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVSINANVRDYLIFAHRSEEQGHQRML
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHEEECCCCEEEEEEEECCHHHHHHHHH
EHLKAKPLLSLGLRLGEGTGAALALPLIQAAVNFYNQMASFSDAGIEAVV
HHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]