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The map label for this gene is ffh [H]

Identifier: 117921457

GI number: 117921457

Start: 3623855

End: 3625228

Strand: Reverse

Name: ffh [H]

Synonym: Shewana3_3018

Alternate gene names: 117921457

Gene position: 3625228-3623855 (Counterclockwise)

Preceding gene: 117921460

Following gene: 117921456

Centisome position: 72.91

GC content: 51.46

Gene sequence:

>1374_bases
ATGTTTGAGAATCTAACCGACAGACTGTCACGCACGCTGAAAAATATCAGTGGCCGTGGTCGCTTAACCGAAGAAAACGT
TAAGGAAACCCTGCGCGAAGTGCGTATGGCGCTGCTGGAGGCCGATGTTGCCCTGCCTGTGGTGCGTGAATTCGTTAACA
ATGTAAAAGAACGTGCCGTTGGTCAGGAAGTGGCGAAGAGCTTAAGTCCTGGTCAAGCCTTTATTAAGATTGTTCAAAGT
GAACTTGAAAAATCCATGGGTGAGGCCAACCAAGCTCTGGATTTAGCCACTCAGCCGCCAGCCGTGGTGATGATGGCGGG
TCTTCAAGGTGCGGGTAAAACGACCAGCGTTGCCAAATTAGGTAAGCTCCTGCGTACGCGCCATAAGAAATCGGTTCTGG
TCGTCAGTGCCGACGTTTACCGCCCTGCAGCGATTAAGCAGCTAGAAACCTTAGCGACCGAAGTCGATGTGGAGTTTTTC
CCATCGGATGTGAGCCAAAAGCCAATCGATATCGCCAAGGCGGCCATTGCCCACGCTAAGCTTAAATTTATCGATGTGGT
GATCCTCGACACTGCGGGCCGTCTGCACGTCGATGAAGCCATGATGGATGAAATCAAGGCGTTGCACGCGGCGGTTAAGC
CGATTGAGACACTGTTCGTGGTCGATGCCATGACGGGTCAAGACGCGGCAAACACGGCTAAAGCCTTTAACGAAGCGCTG
CCGCTCACCGGTGTGATTTTAACTAAGGTCGACGGTGATGCGCGCGGCGGTGCGGCATTATCGATTCGTCATATTACCGG
CAAGCCGATTAAATTCCTCGGTGTTGGCGAGAAGACCGATGCCCTAGAGCCTTTCCATCCAGACCGTATCGCTTCACGTA
TTCTCGGCATGGGCGATGTATTATCGCTTATCGAAGAAGTTGAGCGCGGTGTCGATAAAGACAAAGCGATGAAGCTGGCT
TCCAAAGTGAAGCAGGGCGGAAGTTTTGATCTCGAAGATTTCCGCGAGCAGCTACAGCAGATGAAAAACATGGGCGGCAT
GATGAGCATGATTGAAAAGCTGCCCGGTGTGGGTCAATTGCCACCCGATGCCTTAGCGCAAATCCAAGACGGTAAAATGA
CCCGTCAAATGGAAGCCATCATTAACTCAATGACGGCCAAAGAGCGCAAAAACCCCGATTTAATCAAGGGCTCACGTAAG
CGCCGTATCGCTGCGGGTTCTGGCACACAAATTCAAGACGTGAACCGTTTATTGAAACAGTTTACCCAAATGCAAAAGAT
GATGAAAAAGATGTCGGCCAAGGGCGGCATCCAGAAGATGATGCGCGGAATGCGTGGCATGATGCCTGGCGGCATGAAAT
TTCCTGGCCGTTAA

Upstream 100 bases:

>100_bases
TGCCGAAGTTTACGCAAGTAGGGCATAGCAGTAGCATAATGCGCCCGCATCGTTATAATACAGCCCATTAATCAAGATCC
TAAAGGTATAGAGCAGGACG

Downstream 100 bases:

>100_bases
TGCCAGCGATTTTCATCAAAGTTGATGCTTTATCAGTTGGTTGATTCTATTTGAAATGAGGCGGGCAATCCTAAGGCAGG
TTTAATAATCGCCAGATTTG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAVGQEVAKSLSPGQAFIKIVQS
ELEKSMGEANQALDLATQPPAVVMMAGLQGAGKTTSVAKLGKLLRTRHKKSVLVVSADVYRPAAIKQLETLATEVDVEFF
PSDVSQKPIDIAKAAIAHAKLKFIDVVILDTAGRLHVDEAMMDEIKALHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDVLSLIEEVERGVDKDKAMKLA
SKVKQGGSFDLEDFREQLQQMKNMGGMMSMIEKLPGVGQLPPDALAQIQDGKMTRQMEAIINSMTAKERKNPDLIKGSRK
RRIAAGSGTQIQDVNRLLKQFTQMQKMMKKMSAKGGIQKMMRGMRGMMPGGMKFPGR

Sequences:

>Translated_457_residues
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAVGQEVAKSLSPGQAFIKIVQS
ELEKSMGEANQALDLATQPPAVVMMAGLQGAGKTTSVAKLGKLLRTRHKKSVLVVSADVYRPAAIKQLETLATEVDVEFF
PSDVSQKPIDIAKAAIAHAKLKFIDVVILDTAGRLHVDEAMMDEIKALHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDVLSLIEEVERGVDKDKAMKLA
SKVKQGGSFDLEDFREQLQQMKNMGGMMSMIEKLPGVGQLPPDALAQIQDGKMTRQMEAIINSMTAKERKNPDLIKGSRK
RRIAAGSGTQIQDVNRLLKQFTQMQKMMKKMSAKGGIQKMMRGMRGMMPGGMKFPGR
>Mature_457_residues
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAVGQEVAKSLSPGQAFIKIVQS
ELEKSMGEANQALDLATQPPAVVMMAGLQGAGKTTSVAKLGKLLRTRHKKSVLVVSADVYRPAAIKQLETLATEVDVEFF
PSDVSQKPIDIAKAAIAHAKLKFIDVVILDTAGRLHVDEAMMDEIKALHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDVLSLIEEVERGVDKDKAMKLA
SKVKQGGSFDLEDFREQLQQMKNMGGMMSMIEKLPGVGQLPPDALAQIQDGKMTRQMEAIINSMTAKERKNPDLIKGSRK
RRIAAGSGTQIQDVNRLLKQFTQMQKMMKKMSAKGGIQKMMRGMRGMMPGGMKFPGR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=446, Percent_Identity=33.1838565022422, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI226371618, Length=348, Percent_Identity=34.7701149425287, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI295424842, Length=298, Percent_Identity=29.1946308724832, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI23308697, Length=298, Percent_Identity=29.1946308724832, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI89061728, Length=160, Percent_Identity=37.5, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI1788963, Length=457, Percent_Identity=77.0240700218818, Blast_Score=688, Evalue=0.0,
Organism=Escherichia coli, GI1789874, Length=265, Percent_Identity=32.8301886792453, Blast_Score=149, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=448, Percent_Identity=31.0267857142857, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=201, Percent_Identity=35.3233830845771, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=449, Percent_Identity=31.6258351893096, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320498, Length=316, Percent_Identity=27.8481012658228, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17647949, Length=444, Percent_Identity=32.4324324324324, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24641198, Length=220, Percent_Identity=28.6363636363636, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49866; Mature: 49866

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAV
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVAKSLSPGQAFIKIVQSELEKSMGEANQALDLATQPPAVVMMAGLQGAGKTTSVAKL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCHHHHHH
GKLLRTRHKKSVLVVSADVYRPAAIKQLETLATEVDVEFFPSDVSQKPIDIAKAAIAHAK
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHHH
LKFIDVVILDTAGRLHVDEAMMDEIKALHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
HHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHC
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDV
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
LSLIEEVERGVDKDKAMKLASKVKQGGSFDLEDFREQLQQMKNMGGMMSMIEKLPGVGQL
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
PPDALAQIQDGKMTRQMEAIINSMTAKERKNPDLIKGSRKRRIAAGSGTQIQDVNRLLKQ
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCHHHHHHHHHHH
FTQMQKMMKKMSAKGGIQKMMRGMRGMMPGGMKFPGR
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFENLTDRLSRTLKNISGRGRLTEENVKETLREVRMALLEADVALPVVREFVNNVKERAV
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVAKSLSPGQAFIKIVQSELEKSMGEANQALDLATQPPAVVMMAGLQGAGKTTSVAKL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCHHHHHH
GKLLRTRHKKSVLVVSADVYRPAAIKQLETLATEVDVEFFPSDVSQKPIDIAKAAIAHAK
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHHH
LKFIDVVILDTAGRLHVDEAMMDEIKALHAAVKPIETLFVVDAMTGQDAANTAKAFNEAL
HHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHC
PLTGVILTKVDGDARGGAALSIRHITGKPIKFLGVGEKTDALEPFHPDRIASRILGMGDV
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCHHHH
LSLIEEVERGVDKDKAMKLASKVKQGGSFDLEDFREQLQQMKNMGGMMSMIEKLPGVGQL
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
PPDALAQIQDGKMTRQMEAIINSMTAKERKNPDLIKGSRKRRIAAGSGTQIQDVNRLLKQ
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCHHHHHHHHHHH
FTQMQKMMKKMSAKGGIQKMMRGMRGMMPGGMKFPGR
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]