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The map label for this gene is tadA [H]

Identifier: 117921416

GI number: 117921416

Start: 3578276

End: 3578713

Strand: Direct

Name: tadA [H]

Synonym: Shewana3_2977

Alternate gene names: 117921416

Gene position: 3578276-3578713 (Clockwise)

Preceding gene: 117921415

Following gene: 117921417

Centisome position: 71.97

GC content: 52.97

Gene sequence:

>438_bases
ATGGATGAATTTTTACAGGCCGCGATTGATGAGGCCAAACAAGGACTCGCCGAAGGCGGTATCCCCATTGGTTCAGTATT
AGTGATCGACGGGGAAATTGTCGCCCGCGGCCATAACAAACGCGTGCAGCAAGGCAGCGCCGTGCTGCATGCCGAAATGG
ATTGCCTCGAAAATGCCGGCAGATTGACCGCCGCCGATTACCAAAAGGCCACGCTCTATTCAACCCTTTCCCCCTGCGAT
ATGTGTAGCGGCGCGATTTTACTCTATGGCATCCCTAAGGTGGTGGTCGGTGAAAATGTCACCTTTCAAGGGCCGGAAGC
CTATGTGCAGTCCCGCGGAGTAGAGGTAACAGTGGTGGACAATCACGAGTGCAAACAGTTGATGCACGATTTTATCGCCG
CCAAGCCACAACTGTGGAACGAAGATATTGGTGAATAG

Upstream 100 bases:

>100_bases
ACCCAAGCTTAATCATCAATCGAAATCACCACTTAGGTTGTCTTGCTCAACGCTTGCAGGCTGCTATGCTGAGCCAAACA
GCCTAAGACAGGGGATCGAA

Downstream 100 bases:

>100_bases
CCAATATTTTTTAAGCCTATTATCAATACGGAGCGCACTTGAAAATTACCTTGCACCCTAAATACCAATGGTCAGACTTT
AAACATACCAAACAAATAGA

Product: CMP/dCMP deaminase, zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDEFLQAAIDEAKQGLAEGGIPIGSVLVIDGEIVARGHNKRVQQGSAVLHAEMDCLENAGRLTAADYQKATLYSTLSPCD
MCSGAILLYGIPKVVVGENVTFQGPEAYVQSRGVEVTVVDNHECKQLMHDFIAAKPQLWNEDIGE

Sequences:

>Translated_145_residues
MDEFLQAAIDEAKQGLAEGGIPIGSVLVIDGEIVARGHNKRVQQGSAVLHAEMDCLENAGRLTAADYQKATLYSTLSPCD
MCSGAILLYGIPKVVVGENVTFQGPEAYVQSRGVEVTVVDNHECKQLMHDFIAAKPQLWNEDIGE
>Mature_145_residues
MDEFLQAAIDEAKQGLAEGGIPIGSVLVIDGEIVARGHNKRVQQGSAVLHAEMDCLENAGRLTAADYQKATLYSTLSPCD
MCSGAILLYGIPKVVVGENVTFQGPEAYVQSRGVEVTVVDNHECKQLMHDFIAAKPQLWNEDIGE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=111, Percent_Identity=32.4324324324324, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI145693172, Length=145, Percent_Identity=30.3448275862069, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17541138, Length=106, Percent_Identity=37.7358490566038, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=35.0515463917526, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=144, Percent_Identity=55.5555555555556, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15630; Mature: 15630

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEFLQAAIDEAKQGLAEGGIPIGSVLVIDGEIVARGHNKRVQQGSAVLHAEMDCLENAG
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCHHHCCCCHHHHHHHHHHCCC
RLTAADYQKATLYSTLSPCDMCSGAILLYGIPKVVVGENVTFQGPEAYVQSRGVEVTVVD
CCEECCCHHHHHHHHCCCHHHHCCEEEEECCCHHEECCCCEECCHHHHHHHCCCEEEEEC
NHECKQLMHDFIAAKPQLWNEDIGE
CHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDEFLQAAIDEAKQGLAEGGIPIGSVLVIDGEIVARGHNKRVQQGSAVLHAEMDCLENAG
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCHHHCCCCHHHHHHHHHHCCC
RLTAADYQKATLYSTLSPCDMCSGAILLYGIPKVVVGENVTFQGPEAYVQSRGVEVTVVD
CCEECCCHHHHHHHHCCCHHHHCCEEEEECCCHHEECCCCEECCHHHHHHHCCCEEEEEC
NHECKQLMHDFIAAKPQLWNEDIGE
CHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]