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The map label for this gene is mdtN [H]

Identifier: 117921352

GI number: 117921352

Start: 3487437

End: 3488531

Strand: Direct

Name: mdtN [H]

Synonym: Shewana3_2912

Alternate gene names: 117921352

Gene position: 3487437-3488531 (Clockwise)

Preceding gene: 117921351

Following gene: 117921353

Centisome position: 70.14

GC content: 51.42

Gene sequence:

>1095_bases
ATGACTGACAGTACCGCGACTCCGGGAAAGGCGAGTAAATATGCCACCCTTGGCCTTCTGGCACTCATAGTAATATTACT
GCTTTGGTACCTTGTGGCCGACAGAATGACCCCCTATAGCTCACAGGCAAGGGTCCAAGCCTTTGTGGTGCCGATTGCTA
CCGAAGTCACGGGGCAGATTTTGAAAGTCTATGTGCAGGATAACCAAGATGTCGCCGAGGGCGCTCCCTTATTCGATATC
GATCCTGAGCCCTATGATATTGCCCTTGCCAAAGCCAAGTCTGACTATGAAACAGTGCTAAATAGCGTTAAAGCCAATAA
TGAAGGCGTTAAGGCGGCGGAAGCGAAATTACAAGCCATGCGTGCGTCTTACAATAATTCAGTGAAAGATGCCGAGCGGC
AAGAACGTCTCTATCGCCAAGACCCGGGGGCTATTTCAGTACGCCGACTCGAAATCGCACAAGCATCGCGAGAAACTGCC
AGCAGCCAAGTCACAGCCGCCGAAGCCGATGTTAGGCGCGCCATTGAGGCCGCAGGGGTGAATGGTGAAAACAACTCACA
ACTATTAAGTGCTCGTTCGGCGGTGAATAAAGCCGAGCGCGATAGACAAAATACCCATGTCGTCGCTCCAAGCCGTGGAG
TGATCACCGACTTAAATACCGATGTGGGGCAGTTTATTAACGCGGGCGCCCCCGCAATGACTCTGATTGCTATCCACGAT
GTGTGGATTTCGGCGGATCTGACCGAAAACAATCTCGGCAATATTAAAGTGGGAAACAGAGTCTCTATCCTGCTCGACAG
CATGCCTGGACAGTTATTTAGCGGCCAAATACGCAGTATTGGCTATGGTGTGGATGATGGTAAAAAACAGGCCGTTGGTT
CACTGCCGACTGTCAGTAATAGCCGCGATTGGCTGCGCCAAGCACAACGCTTCCCCGTTAAAGTGTCGTTCTCAGCGGAC
GATATGCCCCCTGCAGCTAACTTGCGTGTGGGAGGCCAAGCCGACATCTTGGTTTATACCGAAGAACATGGCCTGATGAA
CCCGCTCGGTGCACTGTATATTCGGGTAATGAGCCTCTTCTCCTATCTGTATTGA

Upstream 100 bases:

>100_bases
GTGCCCTATCTCGATAACCCATTGTTCGATGCAAATCAGCCCCAAACGGGTTCTCAACCTAATGCCCAGCCTACATCGAC
TATTCAAAAGGGAATTGTGA

Downstream 100 bases:

>100_bases
GGCCTGATATGCACCACGCAGACAGTACAGTACTCAGAATTAGCCTTGGCATCTCATTAGCGGCGTTTGTGTGTTTTGGT
CTAGCCCTGCCCATGCCCCA

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTDSTATPGKASKYATLGLLALIVILLLWYLVADRMTPYSSQARVQAFVVPIATEVTGQILKVYVQDNQDVAEGAPLFDI
DPEPYDIALAKAKSDYETVLNSVKANNEGVKAAEAKLQAMRASYNNSVKDAERQERLYRQDPGAISVRRLEIAQASRETA
SSQVTAAEADVRRAIEAAGVNGENNSQLLSARSAVNKAERDRQNTHVVAPSRGVITDLNTDVGQFINAGAPAMTLIAIHD
VWISADLTENNLGNIKVGNRVSILLDSMPGQLFSGQIRSIGYGVDDGKKQAVGSLPTVSNSRDWLRQAQRFPVKVSFSAD
DMPPAANLRVGGQADILVYTEEHGLMNPLGALYIRVMSLFSYLY

Sequences:

>Translated_364_residues
MTDSTATPGKASKYATLGLLALIVILLLWYLVADRMTPYSSQARVQAFVVPIATEVTGQILKVYVQDNQDVAEGAPLFDI
DPEPYDIALAKAKSDYETVLNSVKANNEGVKAAEAKLQAMRASYNNSVKDAERQERLYRQDPGAISVRRLEIAQASRETA
SSQVTAAEADVRRAIEAAGVNGENNSQLLSARSAVNKAERDRQNTHVVAPSRGVITDLNTDVGQFINAGAPAMTLIAIHD
VWISADLTENNLGNIKVGNRVSILLDSMPGQLFSGQIRSIGYGVDDGKKQAVGSLPTVSNSRDWLRQAQRFPVKVSFSAD
DMPPAANLRVGGQADILVYTEEHGLMNPLGALYIRVMSLFSYLY
>Mature_363_residues
TDSTATPGKASKYATLGLLALIVILLLWYLVADRMTPYSSQARVQAFVVPIATEVTGQILKVYVQDNQDVAEGAPLFDID
PEPYDIALAKAKSDYETVLNSVKANNEGVKAAEAKLQAMRASYNNSVKDAERQERLYRQDPGAISVRRLEIAQASRETAS
SQVTAAEADVRRAIEAAGVNGENNSQLLSARSAVNKAERDRQNTHVVAPSRGVITDLNTDVGQFINAGAPAMTLIAIHDV
WISADLTENNLGNIKVGNRVSILLDSMPGQLFSGQIRSIGYGVDDGKKQAVGSLPTVSNSRDWLRQAQRFPVKVSFSADD
MPPAANLRVGGQADILVYTEEHGLMNPLGALYIRVMSLFSYLY

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=311, Percent_Identity=34.4051446945338, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081951, Length=338, Percent_Identity=26.9230769230769, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790024, Length=360, Percent_Identity=25.8333333333333, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789637, Length=326, Percent_Identity=27.3006134969325, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790012, Length=360, Percent_Identity=24.1666666666667, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788711, Length=287, Percent_Identity=26.4808362369338, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789041, Length=330, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787013, Length=243, Percent_Identity=24.6913580246914, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39443; Mature: 39312

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTATPGKASKYATLGLLALIVILLLWYLVADRMTPYSSQARVQAFVVPIATEVTGQI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHE
LKVYVQDNQDVAEGAPLFDIDPEPYDIALAKAKSDYETVLNSVKANNEGVKAAEAKLQAM
EEEEECCCCCHHCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
RASYNNSVKDAERQERLYRQDPGAISVRRLEIAQASRETASSQVTAAEADVRRAIEAAGV
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NGENNSQLLSARSAVNKAERDRQNTHVVAPSRGVITDLNTDVGQFINAGAPAMTLIAIHD
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEECCCHHHHHHCCCCCCEEEEEEEH
VWISADLTENNLGNIKVGNRVSILLDSMPGQLFSGQIRSIGYGVDDGKKQAVGSLPTVSN
HEEEEECCCCCCCCEEECCEEEEEEECCCCHHHCCHHHHCCCCCCCCHHHHCCCCCCCCC
SRDWLRQAQRFPVKVSFSADDMPPAANLRVGGQADILVYTEEHGLMNPLGALYIRVMSLF
CHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHH
SYLY
HHHC
>Mature Secondary Structure 
TDSTATPGKASKYATLGLLALIVILLLWYLVADRMTPYSSQARVQAFVVPIATEVTGQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHE
LKVYVQDNQDVAEGAPLFDIDPEPYDIALAKAKSDYETVLNSVKANNEGVKAAEAKLQAM
EEEEECCCCCHHCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
RASYNNSVKDAERQERLYRQDPGAISVRRLEIAQASRETASSQVTAAEADVRRAIEAAGV
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NGENNSQLLSARSAVNKAERDRQNTHVVAPSRGVITDLNTDVGQFINAGAPAMTLIAIHD
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEECCCHHHHHHCCCCCCEEEEEEEH
VWISADLTENNLGNIKVGNRVSILLDSMPGQLFSGQIRSIGYGVDDGKKQAVGSLPTVSN
HEEEEECCCCCCCCEEECCEEEEEEECCCCHHHCCHHHHCCCCCCCCHHHHCCCCCCCCC
SRDWLRQAQRFPVKVSFSADDMPPAANLRVGGQADILVYTEEHGLMNPLGALYIRVMSLF
CHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHH
SYLY
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]