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The map label for this gene is btuE [C]

Identifier: 117921316

GI number: 117921316

Start: 3437655

End: 3438140

Strand: Direct

Name: btuE [C]

Synonym: Shewana3_2875

Alternate gene names: 117921316

Gene position: 3437655-3438140 (Clockwise)

Preceding gene: 117921312

Following gene: 117921322

Centisome position: 69.14

GC content: 43.42

Gene sequence:

>486_bases
ATGACATCGACTATCTATAGCCATAGCGCAAACGACATTCAAGGCAATCCAACGGCACTGGCACAATATCAAGGCAAAGT
GATCTTAATTGTGAATACCGCCAGTGAGTGCGGTTTTACACCACAGTACAAGGGCTTAGAAGCGCTCTATCAAAAATATA
AATCACAGGGATTGGTGGTTTTAGGCTTCCCATGCAATCAGTTTGGTGCCCAAGAAAAAGCTGATGAGAAAGGCATCCAA
AGTTTTTGTGAACTCAACTTTGGCGTGAGTTTTCCGCTGTTTTCGAAAATAGAGGTAAACGGTGAGCACACTCACCCTTT
ATATCAGTACCTAAAAAAAGCCGCGCCGGGCGTATTAGGCACAGAACGCATTAAGTGGAATTTCACTAAATTCTTAATTA
ATCGTCAGGGCGAAGTGGTCGCTCGCTTTGCGCCAACCACAAAACCAGAGGCCATTAGTGACAAGATAGAAGCGCTTTTA
AAATAA

Upstream 100 bases:

>100_bases
TTGAAGAAGATTAGCAAATCCACAAAATAAATTGTACACAAATAAATTGATAACAACCAAACTATTATTTATGCTAATCA
CCACACCTAAGGAGGTAATG

Downstream 100 bases:

>100_bases
TCCACACGCTATCCTATTGAAATTTTATTATTAAATAAAAAATTTAAGTTATTTTTTATTTTCGATGGAACTTTAATTCT
ATAAGCCCCTCAAACATATT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTSTIYSHSANDIQGNPTALAQYQGKVILIVNTASECGFTPQYKGLEALYQKYKSQGLVVLGFPCNQFGAQEKADEKGIQ
SFCELNFGVSFPLFSKIEVNGEHTHPLYQYLKKAAPGVLGTERIKWNFTKFLINRQGEVVARFAPTTKPEAISDKIEALL
K

Sequences:

>Translated_161_residues
MTSTIYSHSANDIQGNPTALAQYQGKVILIVNTASECGFTPQYKGLEALYQKYKSQGLVVLGFPCNQFGAQEKADEKGIQ
SFCELNFGVSFPLFSKIEVNGEHTHPLYQYLKKAAPGVLGTERIKWNFTKFLINRQGEVVARFAPTTKPEAISDKIEALL
K
>Mature_160_residues
TSTIYSHSANDIQGNPTALAQYQGKVILIVNTASECGFTPQYKGLEALYQKYKSQGLVVLGFPCNQFGAQEKADEKGIQS
FCELNFGVSFPLFSKIEVNGEHTHPLYQYLKKAAPGVLGTERIKWNFTKFLINRQGEVVARFAPTTKPEAISDKIEALLK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=42.6751592356688, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=41.6666666666667, Blast_Score=121, Evalue=3e-28,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=41.6666666666667, Blast_Score=120, Evalue=4e-28,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=36.25, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI4557629, Length=178, Percent_Identity=39.8876404494382, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=42.7480916030534, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=36.2637362637363, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI6006001, Length=181, Percent_Identity=35.3591160220994, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI33186887, Length=181, Percent_Identity=33.7016574585635, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI32967607, Length=185, Percent_Identity=32.4324324324324, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788003, Length=169, Percent_Identity=44.3786982248521, Blast_Score=155, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=46.875, Blast_Score=148, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=43.3962264150943, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=46.9512195121951, Blast_Score=139, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=39.2405063291139, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=186, Percent_Identity=34.9462365591398, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI193209493, Length=186, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71999642, Length=72, Percent_Identity=43.0555555555556, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193210709, Length=71, Percent_Identity=50.7042253521127, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=35.7894736842105, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17507603, Length=98, Percent_Identity=38.7755102040816, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=51.25, Blast_Score=184, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=51.5723270440252, Blast_Score=184, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=50.3225806451613, Blast_Score=165, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=45.625, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=45.625, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=45.625, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=40.251572327044, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17867; Mature: 17735

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTIYSHSANDIQGNPTALAQYQGKVILIVNTASECGFTPQYKGLEALYQKYKSQGLVV
CCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECHHHCCCCCCCCCHHHHHHHHHHCCEEE
LGFPCNQFGAQEKADEKGIQSFCELNFGVSFPLFSKIEVNGEHTHPLYQYLKKAAPGVLG
EECCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCC
TERIKWNFTKFLINRQGEVVARFAPTTKPEAISDKIEALLK
CCEEEHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TSTIYSHSANDIQGNPTALAQYQGKVILIVNTASECGFTPQYKGLEALYQKYKSQGLVV
CCCCCCCCCCCCCCCCCEEEECCCEEEEEEECHHHCCCCCCCCCHHHHHHHHHHCCEEE
LGFPCNQFGAQEKADEKGIQSFCELNFGVSFPLFSKIEVNGEHTHPLYQYLKKAAPGVLG
EECCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCC
TERIKWNFTKFLINRQGEVVARFAPTTKPEAISDKIEALLK
CCEEEHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]