Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 117921138

GI number: 117921138

Start: 3223185

End: 3224369

Strand: Reverse

Name: nagA [H]

Synonym: Shewana3_2697

Alternate gene names: 117921138

Gene position: 3224369-3223185 (Counterclockwise)

Preceding gene: 117921139

Following gene: 117921137

Centisome position: 64.85

GC content: 54.43

Gene sequence:

>1185_bases
ATGAAGCCTAATACGGATTTTATGCTGATAGCCGACGGCGCTAAGGTGCTAACTCAAGGCAATCTCACAGAGCACTGCGC
GATTGAGGTGTCGGATGGCATTATTTGCGGCCTTAAATCCACAATATCGGCAGAGTGGACAGCGGATAAACCACACTACC
GATTGACCTCTGGCACGCTGGTGGCGGGATTTATCGATACGCAAGTCAATGGCGGTGGGGGCCTGATGTTCAATCATGTA
CCGACGTTGGAAACCTTAAGGTTGATGATGCAGGCCCATCGCCAGTTTGGCACCACGGCCATGCTACCTACGGTGATCAC
CGACGATATTGAGGTGATGCAGGCTGCGGCCGATGCGGTGGCTGAGGCGATAGATTGCCAAGTTCCCGGGATTATCGGAA
TTCATTTTGAAGGCCCGCATTTGTCGGTAGCAAAACGCGGCTGTCACCCTCCCGCACATTTACGCGGCATCACTGAACGC
GAGTGGCTGCTGTACTTAAGGCAAGATCTCGGCGTCAGGCTTATCACTCTAGCGCCAGAATCTGTCACTCCAGAACAAAT
CAAACGCCTCGTGGCCTCCGGTGCCATTATCAGCCTTGGGCATTCGAATGCCGACGGTGAGACAGTCCTTAAGGCCATTG
AGGCCGGCGCATCGGGTTTTACCCACCTCTACAACGGCATGTCTGCATTGACGTCCCGCGAGCCGGGCATGGTGGGCGCG
GCATTTGCCAGTGAAAACACCTACTGCGGGATTATTCTCGATGGTCAACATGTGCATCCCATCTCGGCATTGGCGGCGTG
GCGAGCAAAGGGAACTGAGCACCTGATGTTAGTCACCGATGCCATGTCGCCCTTAGGGAGCGATCAAACGGAATTTCAAT
TCTTCGATGGCAAAGTGGTACGCGAAGGGATGACGCTTAGGGATCAGCATGGCTCTTTAGCGGGCTCTGTGCTGGATATG
GCAAGCGCGGTGCGTTATGCCGCCACCGAACTCAATCTTGGCCTTAGCAACGCAGTACAGATGGCGACACGCACGCCAGC
CGAGTTTATTCAGCGGCCGCAATTGGGGGATATTGCCGAAGGTAAACAGGCTGATTGGGTCTGGCTGGATGATGACCAGA
GAGTTTTAGCTGTCTGGATTGCAGGGGAGTTGTTGTATCAAGCCGAGCAGGCACGGTTTGCATAA

Upstream 100 bases:

>100_bases
GGCGTGACGTTGCCGCAATTTAAATTGGCCGACTTTGGTTCGGCCAGTGGCGTGCGCGGCGCGGCTTTGCTCGGTCACGG
GCTCGATGCGGGGATAAGCT

Downstream 100 bases:

>100_bases
GTTATCGATATATCAATTAAAACAATAACTAAAGCGGCATTTATTTGGGTGAGCTAAGTACTCAACCCATGGCCCATTCA
ACAAGCAAAATAACAATAAA

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKPNTDFMLIADGAKVLTQGNLTEHCAIEVSDGIICGLKSTISAEWTADKPHYRLTSGTLVAGFIDTQVNGGGGLMFNHV
PTLETLRLMMQAHRQFGTTAMLPTVITDDIEVMQAAADAVAEAIDCQVPGIIGIHFEGPHLSVAKRGCHPPAHLRGITER
EWLLYLRQDLGVRLITLAPESVTPEQIKRLVASGAIISLGHSNADGETVLKAIEAGASGFTHLYNGMSALTSREPGMVGA
AFASENTYCGIILDGQHVHPISALAAWRAKGTEHLMLVTDAMSPLGSDQTEFQFFDGKVVREGMTLRDQHGSLAGSVLDM
ASAVRYAATELNLGLSNAVQMATRTPAEFIQRPQLGDIAEGKQADWVWLDDDQRVLAVWIAGELLYQAEQARFA

Sequences:

>Translated_394_residues
MKPNTDFMLIADGAKVLTQGNLTEHCAIEVSDGIICGLKSTISAEWTADKPHYRLTSGTLVAGFIDTQVNGGGGLMFNHV
PTLETLRLMMQAHRQFGTTAMLPTVITDDIEVMQAAADAVAEAIDCQVPGIIGIHFEGPHLSVAKRGCHPPAHLRGITER
EWLLYLRQDLGVRLITLAPESVTPEQIKRLVASGAIISLGHSNADGETVLKAIEAGASGFTHLYNGMSALTSREPGMVGA
AFASENTYCGIILDGQHVHPISALAAWRAKGTEHLMLVTDAMSPLGSDQTEFQFFDGKVVREGMTLRDQHGSLAGSVLDM
ASAVRYAATELNLGLSNAVQMATRTPAEFIQRPQLGDIAEGKQADWVWLDDDQRVLAVWIAGELLYQAEQARFA
>Mature_394_residues
MKPNTDFMLIADGAKVLTQGNLTEHCAIEVSDGIICGLKSTISAEWTADKPHYRLTSGTLVAGFIDTQVNGGGGLMFNHV
PTLETLRLMMQAHRQFGTTAMLPTVITDDIEVMQAAADAVAEAIDCQVPGIIGIHFEGPHLSVAKRGCHPPAHLRGITER
EWLLYLRQDLGVRLITLAPESVTPEQIKRLVASGAIISLGHSNADGETVLKAIEAGASGFTHLYNGMSALTSREPGMVGA
AFASENTYCGIILDGQHVHPISALAAWRAKGTEHLMLVTDAMSPLGSDQTEFQFFDGKVVREGMTLRDQHGSLAGSVLDM
ASAVRYAATELNLGLSNAVQMATRTPAEFIQRPQLGDIAEGKQADWVWLDDDQRVLAVWIAGELLYQAEQARFA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=382, Percent_Identity=31.9371727748691, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI224922791, Length=375, Percent_Identity=31.2, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1786892, Length=382, Percent_Identity=35.8638743455497, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17553768, Length=404, Percent_Identity=29.9504950495049, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19920392, Length=386, Percent_Identity=34.4559585492228, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI281361140, Length=398, Percent_Identity=33.6683417085427, Blast_Score=164, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42411; Mature: 42411

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNTDFMLIADGAKVLTQGNLTEHCAIEVSDGIICGLKSTISAEWTADKPHYRLTSGTL
CCCCCCEEEEECCCEEEECCCCCCEEEEEECCCEEECCCCCCCCCCCCCCCCEEEECCCE
VAGFIDTQVNGGGGLMFNHVPTLETLRLMMQAHRQFGTTAMLPTVITDDIEVMQAAADAV
EEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCHHHCCHHHHCHHHHHHHHHHHH
AEAIDCQVPGIIGIHFEGPHLSVAKRGCHPPAHLRGITEREWLLYLRQDLGVRLITLAPE
HHHHCCCCCCEEEEEECCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHCCEEEEEECCC
SVTPEQIKRLVASGAIISLGHSNADGETVLKAIEAGASGFTHLYNGMSALTSREPGMVGA
CCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEE
AFASENTYCGIILDGQHVHPISALAAWRAKGTEHLMLVTDAMSPLGSDQTEFQFFDGKVV
EEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEECCEEE
REGMTLRDQHGSLAGSVLDMASAVRYAATELNLGLSNAVQMATRTPAEFIQRPQLGDIAE
ECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCC
GKQADWVWLDDDQRVLAVWIAGELLYQAEQARFA
CCCCCEEEECCCCEEEEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPNTDFMLIADGAKVLTQGNLTEHCAIEVSDGIICGLKSTISAEWTADKPHYRLTSGTL
CCCCCCEEEEECCCEEEECCCCCCEEEEEECCCEEECCCCCCCCCCCCCCCCEEEECCCE
VAGFIDTQVNGGGGLMFNHVPTLETLRLMMQAHRQFGTTAMLPTVITDDIEVMQAAADAV
EEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCHHHCCHHHHCHHHHHHHHHHHH
AEAIDCQVPGIIGIHFEGPHLSVAKRGCHPPAHLRGITEREWLLYLRQDLGVRLITLAPE
HHHHCCCCCCEEEEEECCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHCCEEEEEECCC
SVTPEQIKRLVASGAIISLGHSNADGETVLKAIEAGASGFTHLYNGMSALTSREPGMVGA
CCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEE
AFASENTYCGIILDGQHVHPISALAAWRAKGTEHLMLVTDAMSPLGSDQTEFQFFDGKVV
EEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEECCEEE
REGMTLRDQHGSLAGSVLDMASAVRYAATELNLGLSNAVQMATRTPAEFIQRPQLGDIAE
ECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCC
GKQADWVWLDDDQRVLAVWIAGELLYQAEQARFA
CCCCCEEEECCCCEEEEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]